(16 nodes) Peptidyl-proline hydroxylation network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P3H1	Prolyl 3-hydroxylase 1. (797 aa)
	P4HB	Protein disulfide-isomerase. (513 aa)
	ERO1A	Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
	P3H3	Prolyl 3-hydroxylase 3. (647 aa)
	METTL26	Uncharacterized protein. (127 aa)
	PRDX4	Peroxiredoxin 4. (271 aa)
	CRTAP	Cartilage associated protein. (343 aa)
	P3H2	Prolyl 3-hydroxylase 2. (636 aa)
	EGLN2	Egl-9 family hypoxia inducible factor 2. (407 aa)
	OGFOD1	2-oxoglutarate and iron dependent oxygenase domain containing 1. (542 aa)
	P4HA1	Prolyl 4-hydroxylase subunit alpha 1. (527 aa)
	EGLN1	Fe2OG dioxygenase domain-containing protein. (341 aa)
	P4HA2	Prolyl 4-hydroxylase subunit alpha 2. (535 aa)
	EGLN3	Egl-9 family hypoxia inducible factor 3. (239 aa)
	P4HTM	Prolyl 4-hydroxylase, transmembrane. (529 aa)
	P4HA3	Prolyl 4-hydroxylase subunit alpha 3. (543 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTAP	P3H1	ENSPPAP00000033704	ENSPPAP00000037158	Cartilage associated protein.	Prolyl 3-hydroxylase 1.	0.993
CRTAP	P3H2	ENSPPAP00000033704	ENSPPAP00000034333	Cartilage associated protein.	Prolyl 3-hydroxylase 2.	0.653
CRTAP	P3H3	ENSPPAP00000033704	ENSPPAP00000027478	Cartilage associated protein.	Prolyl 3-hydroxylase 3.	0.659
CRTAP	P4HB	ENSPPAP00000033704	ENSPPAP00000024772	Cartilage associated protein.	Protein disulfide-isomerase.	0.587
EGLN1	EGLN2	ENSPPAP00000013832	ENSPPAP00000020601	Fe2OG dioxygenase domain-containing protein.	Egl-9 family hypoxia inducible factor 2.	0.954
EGLN1	EGLN3	ENSPPAP00000013832	ENSPPAP00000004299	Fe2OG dioxygenase domain-containing protein.	Egl-9 family hypoxia inducible factor 3.	0.967
EGLN1	P4HA1	ENSPPAP00000013832	ENSPPAP00000014208	Fe2OG dioxygenase domain-containing protein.	Prolyl 4-hydroxylase subunit alpha 1.	0.564
EGLN1	P4HA2	ENSPPAP00000013832	ENSPPAP00000011230	Fe2OG dioxygenase domain-containing protein.	Prolyl 4-hydroxylase subunit alpha 2.	0.550
EGLN1	P4HTM	ENSPPAP00000013832	ENSPPAP00000023502	Fe2OG dioxygenase domain-containing protein.	Prolyl 4-hydroxylase, transmembrane.	0.463
EGLN2	EGLN1	ENSPPAP00000020601	ENSPPAP00000013832	Egl-9 family hypoxia inducible factor 2.	Fe2OG dioxygenase domain-containing protein.	0.954
EGLN2	EGLN3	ENSPPAP00000020601	ENSPPAP00000004299	Egl-9 family hypoxia inducible factor 2.	Egl-9 family hypoxia inducible factor 3.	0.967
EGLN2	P4HA1	ENSPPAP00000020601	ENSPPAP00000014208	Egl-9 family hypoxia inducible factor 2.	Prolyl 4-hydroxylase subunit alpha 1.	0.472
EGLN2	P4HA2	ENSPPAP00000020601	ENSPPAP00000011230	Egl-9 family hypoxia inducible factor 2.	Prolyl 4-hydroxylase subunit alpha 2.	0.472
EGLN2	P4HTM	ENSPPAP00000020601	ENSPPAP00000023502	Egl-9 family hypoxia inducible factor 2.	Prolyl 4-hydroxylase, transmembrane.	0.480
EGLN3	EGLN1	ENSPPAP00000004299	ENSPPAP00000013832	Egl-9 family hypoxia inducible factor 3.	Fe2OG dioxygenase domain-containing protein.	0.967
EGLN3	EGLN2	ENSPPAP00000004299	ENSPPAP00000020601	Egl-9 family hypoxia inducible factor 3.	Egl-9 family hypoxia inducible factor 2.	0.967
EGLN3	P4HA1	ENSPPAP00000004299	ENSPPAP00000014208	Egl-9 family hypoxia inducible factor 3.	Prolyl 4-hydroxylase subunit alpha 1.	0.497
EGLN3	P4HA2	ENSPPAP00000004299	ENSPPAP00000011230	Egl-9 family hypoxia inducible factor 3.	Prolyl 4-hydroxylase subunit alpha 2.	0.484
EGLN3	P4HTM	ENSPPAP00000004299	ENSPPAP00000023502	Egl-9 family hypoxia inducible factor 3.	Prolyl 4-hydroxylase, transmembrane.	0.472
ERO1A	P4HB	ENSPPAP00000024994	ENSPPAP00000024772	Endoplasmic reticulum oxidoreductase 1 alpha.	Protein disulfide-isomerase.	0.992