(32 nodes) Cranial nerve morphogenesis network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	HOXA1	Homeobox A1. (336 aa)
	NEUROG1	Neurogenin 1. (237 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (924 aa)
	TIFAB	TIFA inhibitor. (161 aa)
	PAX2	Paired box 2. (417 aa)
	KCNA2	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
	MAFB	MAF bZIP transcription factor B. (323 aa)
	EPHB1	EPH receptor B1. (984 aa)
	ADARB1	Adenosine deaminase RNA specific B1. (741 aa)
	HOXB2	Homeobox B2. (356 aa)
	DCANP1	Dendritic cell associated nuclear protein. (237 aa)
	HOXD3	Homeobox D3. (432 aa)
	CHRNB2	Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
	TBX1	Uncharacterized protein. (447 aa)
	HOXA3	Homeobox A3. (443 aa)
	HOXB3	Homeobox B3. (413 aa)
	EPHB2	EPH receptor B2. (1039 aa)
	ENSPPAP00000019871	Homeobox domain-containing protein. (224 aa)
	PLXNA4	Sema domain-containing protein. (1553 aa)
	EGR2	Early growth response 2. (476 aa)
	PLXNA3	Plexin A3. (1871 aa)
	ENSPPAP00000032305	Plexin_cytopl domain-containing protein. (238 aa)
	HOXB1	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily. (301 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (785 aa)
	DMD	Dystrophin. (3517 aa)
	GLI3	GLI family zinc finger 3. (1580 aa)
	CITED2	Uncharacterized protein. (179 aa)
	ATP8B1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
	TFAP2A	TF_AP-2 domain-containing protein. (328 aa)
	ATP8B3	Uncharacterized protein. (1194 aa)
	PLXNA1	Plexin A1. (1915 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CITED2	TFAP2A	ENSPPAP00000041025	ENSPPAP00000041376	Uncharacterized protein.	TF_AP-2 domain-containing protein.	0.898
EGR2	HOXB1	ENSPPAP00000025890	ENSPPAP00000032487	Early growth response 2.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.591
EGR2	HOXB2	ENSPPAP00000025890	ENSPPAP00000008358	Early growth response 2.	Homeobox B2.	0.594
EGR2	MAFB	ENSPPAP00000025890	ENSPPAP00000005158	Early growth response 2.	MAF bZIP transcription factor B.	0.469
ENSPPAP00000032305	NRP1	ENSPPAP00000032305	ENSPPAP00000000240	Plexin_cytopl domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.903
ENSPPAP00000032305	NRP2	ENSPPAP00000032305	ENSPPAP00000036618	Plexin_cytopl domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.692
ENSPPAP00000032305	PLXNA1	ENSPPAP00000032305	ENSPPAP00000041954	Plexin_cytopl domain-containing protein.	Plexin A1.	0.658
ENSPPAP00000032305	PLXNA4	ENSPPAP00000032305	ENSPPAP00000021530	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.893
ENSPPAP00000032305	SEMA3F	ENSPPAP00000032305	ENSPPAP00000037542	Plexin_cytopl domain-containing protein.	Semaphorin 3F; Belongs to the semaphorin family.	0.664
EPHB2	PLXNA1	ENSPPAP00000019552	ENSPPAP00000041954	EPH receptor B2.	Plexin A1.	0.431
EPHB2	SEMA3F	ENSPPAP00000019552	ENSPPAP00000037542	EPH receptor B2.	Semaphorin 3F; Belongs to the semaphorin family.	0.489
HOXA1	HOXB1	ENSPPAP00000000071	ENSPPAP00000032487	Homeobox A1.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.935
HOXA3	HOXB1	ENSPPAP00000018887	ENSPPAP00000032487	Homeobox A3.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.466
HOXB1	EGR2	ENSPPAP00000032487	ENSPPAP00000025890	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Early growth response 2.	0.591
HOXB1	HOXA1	ENSPPAP00000032487	ENSPPAP00000000071	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Homeobox A1.	0.935
HOXB1	HOXA3	ENSPPAP00000032487	ENSPPAP00000018887	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Homeobox A3.	0.466
HOXB1	HOXB2	ENSPPAP00000032487	ENSPPAP00000008358	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Homeobox B2.	0.535
HOXB1	HOXB3	ENSPPAP00000032487	ENSPPAP00000018930	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Homeobox B3.	0.431
HOXB1	MAFB	ENSPPAP00000032487	ENSPPAP00000005158	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	MAF bZIP transcription factor B.	0.402
HOXB1	TBX1	ENSPPAP00000032487	ENSPPAP00000018792	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Uncharacterized protein.	0.459