STRINGSTRING
EREG EREG ESR1 ESR1 SIRT1 SIRT1 A2M A2M PGR PGR CGA CGA CASP2 CASP2 PAM PAM AFP AFP TNFAIP6 TNFAIP6 TGFB2 TGFB2 GPR149 GPR149 TGFB3 TGFB3 LHCGR LHCGR FSHR FSHR SLIT3 SLIT3 NR5A1 NR5A1 PTX3 PTX3 SGPL1 SGPL1 KISS1 KISS1 INHBA INHBA MAP2K6 MAP2K6 RESP18 RESP18 GAS2 GAS2 FSHB FSHB SCAPER SCAPER NOS3 NOS3 ARRB2 ARRB2 STAT5B STAT5B ADAMTS1 ADAMTS1 FZD4 FZD4 MMP2 MMP2 SRC SRC PTPRN PTPRN ROBO2 ROBO2 HSPA5 HSPA5 SLIT2 SLIT2 PLEKHA1 PLEKHA1 NRIP1 NRIP1 MMP19 MMP19 ZNF830 ZNF830 BMPR1B BMPR1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EREGEpiregulin. (169 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
SIRT1Sirtuin 1. (693 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (636 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (147 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (974 aa)
AFPAlpha fetoprotein. (609 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GPR149G protein-coupled receptor 149. (731 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
SLIT3Slit guidance ligand 3. (1527 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
PTX3Pentraxin 3. (380 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
KISS1KiSS-1 metastasis suppressor. (138 aa)
INHBAInhibin subunit beta A. (426 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
RESP18Regulated endocrine specific protein 18. (228 aa)
GAS2Growth arrest specific 2. (314 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1392 aa)
NOS3Nitric oxide synthase 3. (997 aa)
ARRB2Arrestin beta 2. (447 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
MMP2Matrix metallopeptidase 2. (664 aa)
SRCTyrosine-protein kinase. (458 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (973 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
SLIT2Slit guidance ligand 2. (1410 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
MMP19Matrix metallopeptidase 19. (505 aa)
ZNF830Zinc finger protein 830. (392 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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