STRINGSTRING
TWSG1 TWSG1 HES1 HES1 GATA4 GATA4 KCP KCP GDF2 GDF2 FKBP8 FKBP8 GATA6 GATA6 BMPR2 BMPR2 GDF5 GDF5 SMAD4 SMAD4 BMP4 BMP4 ILK ILK NOTCH2 NOTCH2 NUMA1 NUMA1 CRB2 CRB2 ENG ENG MSX1 MSX1 TBX20 TBX20 KIAA1324L KIAA1324L RNF165 RNF165 SMAD2 SMAD2 ACVRL1 ACVRL1 CDH5 CDH5 CCN1 CCN1 PELO PELO ZNF423 ZNF423 NOTCH1 NOTCH1 FBXL15 FBXL15 SULF1 SULF1 UBE2O UBE2O RBPJ RBPJ KDR KDR NEO1 NEO1 SCUBE3 SCUBE3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
GATA4GATA binding protein 4. (396 aa)
KCPKielin cysteine rich BMP regulator. (1595 aa)
GDF2Growth differentiation factor 2. (429 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
GATA6Uncharacterized protein. (402 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
GDF5Growth differentiation factor 5. (501 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMP4TGF_BETA_2 domain-containing protein. (402 aa)
ILKIntegrin linked kinase. (533 aa)
NOTCH2Notch receptor 2. (2254 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2115 aa)
CRB2Crumbs cell polarity complex component 2. (1083 aa)
ENGEndoglin. (658 aa)
MSX1Msh homeobox 1. (249 aa)
TBX20Uncharacterized protein. (379 aa)
KIAA1324LKIAA1324 like. (1015 aa)
RNF165Ring finger protein 165. (346 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
CCN1Cellular communication network factor 1. (381 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
ZNF423Zinc finger protein 423. (1284 aa)
NOTCH1Notch receptor 1. (2573 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1235 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (499 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NEO1Neogenin 1. (1444 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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