STRINGSTRING
SNRPF SNRPF LSM5 LSM5 PHF5A PHF5A PRPF6 PRPF6 SF3B2 SF3B2 SF3B5 SF3B5 HEXIM1 HEXIM1 SNRNP40 SNRNP40 LSM11 LSM11 ENSPPAP00000005283 ENSPPAP00000005283 LSM10 LSM10 HTATSF1 HTATSF1 LUC7L3 LUC7L3 SNU13 SNU13 LSM7 LSM7 SF3B3 SF3B3 ENSPPAP00000007986 ENSPPAP00000007986 SNRPN SNRPN PRPF39 PRPF39 SF3B6 SF3B6 SNRPB2 SNRPB2 PRPF40B PRPF40B ENSPPAP00000010420 ENSPPAP00000010420 LOC100980885 LOC100980885 USP39 USP39 ENSPPAP00000011513 ENSPPAP00000011513 SNRPG SNRPG EFTUD2 EFTUD2 ENSPPAP00000013733 ENSPPAP00000013733 GEMIN4 GEMIN4 SART1 SART1 CD2BP2 CD2BP2 PRPF3 PRPF3 C19orf54 C19orf54 MEPCE MEPCE SNRPA1 SNRPA1 PRPF31 PRPF31 LSM2 LSM2 SLU7 SLU7 SNRPA SNRPA TXNL4B TXNL4B LSM3 LSM3 SF3A3 SF3A3 ZMAT2 ZMAT2 PPIH PPIH TXNL4A TXNL4A SF3B1 SF3B1 SNRNP70 SNRNP70 ENSPPAP00000025338 ENSPPAP00000025338 ENSPPAP00000025450 ENSPPAP00000025450 SNRPB SNRPB ENSPPAP00000027407 ENSPPAP00000027407 RBM42 RBM42 ENSPPAP00000028920 ENSPPAP00000028920 ENSPPAP00000029044 ENSPPAP00000029044 ENSPPAP00000029046 ENSPPAP00000029046 FMC1-LUC7L2 FMC1-LUC7L2 SNRNP27 SNRNP27 SF3A2 SF3A2 DDX23 DDX23 LSM6 LSM6 DDX46 DDX46 SNRPD2 SNRPD2 LARP7 LARP7 AAR2 AAR2 ENSPPAP00000031761 ENSPPAP00000031761 TGS1 TGS1 SNRPD3 SNRPD3 SNIP1 SNIP1 ENSPPAP00000034229 ENSPPAP00000034229 PRPF40A PRPF40A ENSPPAP00000036002 ENSPPAP00000036002 BUD13 BUD13 SF3B4 SF3B4 SNRPE SNRPE ARFGEF1 ARFGEF1 SNRNP200 SNRNP200 LUC7L LUC7L PRPF4 PRPF4 SF3A1 SF3A1 PRPF18 PRPF18 ENSPPAP00000038781 ENSPPAP00000038781 RBMX2 RBMX2 SNRPD1 SNRPD1 PRPF8 PRPF8 DDX39B DDX39B LSM8 LSM8 ENSPPAP00000041319 ENSPPAP00000041319 ENSPPAP00000041652 ENSPPAP00000041652 ENSPPAP00000042401 ENSPPAP00000042401 SNRPC SNRPC ENSPPAP00000042775 ENSPPAP00000042775 LSM4 LSM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPFSm domain-containing protein. (127 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
PHF5APHD finger protein 5A. (110 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
SF3B2Splicing factor 3b subunit 2. (898 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
LSM11Sm domain-containing protein. (300 aa)
ENSPPAP00000005283Uncharacterized protein. (65 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
HTATSF1HIV-1 Tat specific factor 1. (755 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (477 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
ENSPPAP00000007986RRM domain-containing protein. (298 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (244 aa)
PRPF39Pre-mRNA processing factor 39. (669 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (891 aa)
ENSPPAP00000010420RRM domain-containing protein. (193 aa)
LOC100980885LRRcap domain-containing protein. (194 aa)
USP39Ubiquitin specific peptidase 39. (553 aa)
ENSPPAP00000011513RRM domain-containing protein. (304 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
ENSPPAP00000013733Uncharacterized protein. (399 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1058 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (341 aa)
PRPF3Pre-mRNA processing factor 3. (682 aa)
C19orf54Chromosome 19 open reading frame 54. (351 aa)
MEPCEMethylphosphate capping enzyme. (688 aa)
SNRPA1LRRcap domain-containing protein. (255 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
ENSPPAP00000025338Uncharacterized protein. (56 aa)
ENSPPAP00000025450SNRNP27 domain-containing protein. (142 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
ENSPPAP00000027407Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (78 aa)
RBM42RNA binding motif protein 42. (479 aa)
ENSPPAP00000028920Sm domain-containing protein. (74 aa)
ENSPPAP00000029044Sm domain-containing protein. (78 aa)
ENSPPAP00000029046Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (448 aa)
SNRNP27SNRNP27 domain-containing protein. (158 aa)
SF3A2Matrin-type domain-containing protein. (423 aa)
DDX23DEAD-box helicase 23. (820 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
DDX46DEAD-box helicase 46. (1031 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
LARP7La ribonucleoprotein domain family member 7. (588 aa)
AAR2AAR2 splicing factor. (384 aa)
ENSPPAP00000031761Uncharacterized protein; Belongs to the DEAD box helicase family. (720 aa)
TGS1Trimethylguanosine synthase 1. (855 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SNIP1Smad nuclear interacting protein 1. (396 aa)
ENSPPAP00000034229Uncharacterized protein. (421 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (941 aa)
ENSPPAP00000036002Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (67 aa)
BUD13BUD13 homolog. (619 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1836 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
LUC7LLUC7 like. (361 aa)
PRPF4Pre-mRNA processing factor 4. (539 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
PRPF18Pre-mRNA processing factor 18. (351 aa)
ENSPPAP00000038781Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
RBMX2RNA binding motif protein X-linked 2. (321 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
DDX39BDExD-box helicase 39B. (428 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (75 aa)
ENSPPAP00000041319Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (68 aa)
ENSPPAP00000041652Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa)
ENSPPAP00000042401PWI domain-containing protein. (593 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
ENSPPAP00000042775Sm domain-containing protein. (81 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (238 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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