STRINGSTRING
RAB9B RAB9B DNM2 DNM2 HLA-C HLA-C CALR CALR INPP5B INPP5B RAB23 RAB23 LOC100986914 LOC100986914 VAMP3 VAMP3 TLR1 TLR1 OCRL OCRL RAB31 RAB31 TAPBP TAPBP RAB9A RAB9A RAB43 RAB43 TLR2 TLR2 SNAP23 SNAP23 RILP RILP RAB32 RAB32 CYBB CYBB PIP4P1 PIP4P1 RAB11B RAB11B LAMP2 LAMP2 HLA-B HLA-B PIK3C3 PIK3C3 TCIRG1 TCIRG1 PIK3R4 PIK3R4 IRGM IRGM RAB22A RAB22A RAC2 RAC2 VAMP8 VAMP8 HLA-G HLA-G RAB10 RAB10 CORO1A CORO1A ATP6V0A4 ATP6V0A4 ATP6V0E2 ATP6V0E2 VAMP7 VAMP7 ATP6V0D2 ATP6V0D2 RAB20 RAB20 Papa-A Papa-A ANXA3 ANXA3 STX4 STX4 ENSPPAP00000021390 ENSPPAP00000021390 ENSPPAP00000021549 ENSPPAP00000021549 HVCN1 HVCN1 ATP6V0A1 ATP6V0A1 PIP4P2 PIP4P2 LAMP1 LAMP1 SLC11A1 SLC11A1 MCOLN1 MCOLN1 ENSPPAP00000025599 ENSPPAP00000025599 ATP6V0A2 ATP6V0A2 ATG12 ATG12 RAB38 RAB38 ATP6V0E1 ATP6V0E1 RAB34 RAB34 RAB7B RAB7B RAB8B RAB8B PIKFYVE PIKFYVE ATP6V0B ATP6V0B ATP6V0D1 ATP6V0D1 RAB11FIP1 RAB11FIP1 ATG5 ATG5 RAB8A RAB8A CLEC4E CLEC4E ATP6V0C ATP6V0C RAB5A RAB5A APPL2 APPL2 SYT7 SYT7 ATP7A ATP7A RAB39A RAB39A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB9BRAB9B, member RAS oncogene family. (201 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (785 aa)
HLA-CMajor histocompatibility complex, class I, C; Belongs to the MHC class I family. (397 aa)
CALRCalreticulin. (417 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (997 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
LOC100986914Uncharacterized protein. (210 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (116 aa)
TLR1Toll-like receptor. (786 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (887 aa)
RAB31RAB31, member RAS oncogene family. (183 aa)
TAPBPTAP binding protein. (466 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
RILPUncharacterized protein. (348 aa)
RAB32RAB32, member RAS oncogene family. (220 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
RAB11BUncharacterized protein. (221 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
HLA-BIg-like domain-containing protein; Belongs to the MHC class I family. (384 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (916 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
IRGMImmunity related GTPase M. (195 aa)
RAB22ARAB22A, member RAS oncogene family. (194 aa)
RAC2Rac family small GTPase 2. (192 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
HLA-GMajor histocompatibility complex, class I, G; Belongs to the MHC class I family. (355 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (782 aa)
ATP6V0E2ATPase H+ transporting V0 subunit e2. (213 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (260 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
RAB20RAB20, member RAS oncogene family. (234 aa)
Papa-AIGc1 domain-containing protein; Belongs to the MHC class I family. (406 aa)
ANXA3Annexin. (323 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
ENSPPAP00000021390IGc1 domain-containing protein; Belongs to the MHC class I family. (351 aa)
ENSPPAP00000021549Uncharacterized protein. (160 aa)
HVCN1Hydrogen voltage gated channel 1. (274 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (243 aa)
LAMP1Lysosomal associated membrane protein 1. (465 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
MCOLN1Mucolipin 1. (580 aa)
ENSPPAP00000025599Uncharacterized protein. (195 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (181 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
RAB34RAB34, member RAS oncogene family. (268 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (261 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (392 aa)
RAB11FIP1RAB11 family interacting protein 1. (1159 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
CLEC4EC-type lectin domain-containing protein. (174 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (647 aa)
SYT7Uncharacterized protein. (686 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]