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BCL2L1 BCL2L1 MCTP2 MCTP2 RAB3C RAB3C PTPRN2 PTPRN2 LOC100982471 LOC100982471 LOC100988977 LOC100988977 LOC100990258 LOC100990258 MAL2 MAL2 LAMP5 LAMP5 SLC18A2 SLC18A2 SEPTIN8 SEPTIN8 DNAJC5 DNAJC5 VAMP2 VAMP2 SNCA SNCA ATP6V1B1 ATP6V1B1 SLC17A5 SLC17A5 ABCC8 ABCC8 RAB35 RAB35 CLTB CLTB ATP6V1F ATP6V1F SVOP SVOP GABRA2 GABRA2 SV2A SV2A GRIA1 GRIA1 RAB11B RAB11B SV2B SV2B SYN1 SYN1 UNC13C UNC13C RAB3A RAB3A SLC30A3 SLC30A3 SYT1 SYT1 ENSPPAP00000012290 ENSPPAP00000012290 ENSPPAP00000013091 ENSPPAP00000013091 SLC17A6 SLC17A6 SYT12 SYT12 SNAP47 SNAP47 ATP6V1C1 ATP6V1C1 UNC13A UNC13A SYNDIG1 SYNDIG1 SYNGR2 SYNGR2 PTPRS PTPRS ICA1 ICA1 BORCS5 BORCS5 SYT5 SYT5 DOC2A DOC2A ATP6V0E2 ATP6V0E2 ATP6V1G2 ATP6V1G2 SYP SYP DGKI DGKI SYN3 SYN3 ENSPPAP00000020911 ENSPPAP00000020911 SYT6 SYT6 PRRT1 PRRT1 GAD2 GAD2 SYPL1 SYPL1 TPRG1L TPRG1L ATP6V0A1 ATP6V0A1 VAMP1 VAMP1 SYT4 SYT4 SYT2 SYT2 RPH3A RPH3A ATP6AP1 ATP6AP1 SEMA4C SEMA4C ZNRF1 ZNRF1 SNAPIN SNAPIN ENSPPAP00000027450 ENSPPAP00000027450 UNC13B UNC13B SYNPR SYNPR STX16 STX16 CALM3 CALM3 ATP6V1E1 ATP6V1E1 BSN BSN SCAMP1 SCAMP1 SLC32A1 SLC32A1 C16orf70 C16orf70 SLC18A1 SLC18A1 RAB27B RAB27B SYT8 SYT8 SYN2 SYN2 ATP2B1 ATP2B1 MCTP1 MCTP1 CBARP CBARP RAB3B RAB3B BIN1 BIN1 STX1A STX1A SYNGR1 SYNGR1 SYNGR4 SYNGR4 ATP6V1B2 ATP6V1B2 SLC6A9 SLC6A9 CPLX3 CPLX3 RAB26 RAB26 SCAMP5 SCAMP5 STX6 STX6 DMD DMD AMPH AMPH SYPL2 SYPL2 SLC17A7 SLC17A7 SLC6A17 SLC6A17 SV2C SV2C STX10 STX10 CLCN3 CLCN3 ENSPPAP00000038758 ENSPPAP00000038758 PRRT2 PRRT2 SYT7 SYT7 RAB5A RAB5A OPRD1 OPRD1 SLC17A8 SLC17A8 SYT9 SYT9 ATP6V0C ATP6V0C STX12 STX12 LRRK2 LRRK2 SLC9B2 SLC9B2 ENSPPAP00000035589 ENSPPAP00000035589 CLTA CLTA ATP6AP2 ATP6AP2 DNM1L DNM1L ENSPPAP00000033799 ENSPPAP00000033799 DMXL2 DMXL2 OTOF OTOF WFS1 WFS1 DTNBP1 DTNBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL2L1BCL2 like 1. (233 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (934 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (977 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
LOC100988977MARVEL domain-containing protein. (170 aa)
LOC100990258V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (149 aa)
LAMP5Lysosomal associated membrane protein family member 5. (280 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (482 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
SLC17A5Solute carrier family 17 member 5. (495 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
RAB35Uncharacterized protein. (348 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (180 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
SVOPSV2 related protein. (548 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
RAB11BUncharacterized protein. (221 aa)
SV2BSynaptic vesicle glycoprotein 2B. (683 aa)
SYN1Uncharacterized protein. (538 aa)
UNC13CC2 domain-containing protein. (135 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
SLC30A3Solute carrier family 30 member 3. (388 aa)
SYT1Synaptotagmin 1. (422 aa)
ENSPPAP00000012290Uncharacterized protein. (285 aa)
ENSPPAP00000013091Uncharacterized protein. (176 aa)
SLC17A6Solute carrier family 17 member 6. (577 aa)
SYT12Synaptotagmin 12. (420 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
UNC13AUnc-13 homolog A. (1628 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
SYNGR2MARVEL domain-containing protein. (191 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1873 aa)
ICA1Islet cell autoantigen 1. (511 aa)
BORCS5BLOC-1 related complex subunit 5. (196 aa)
SYT5Synaptotagmin 5. (408 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
ATP6V0E2ATPase H+ transporting V0 subunit e2. (213 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
SYPSynaptophysin. (313 aa)
DGKIDiacylglycerol kinase. (905 aa)
SYN3Synapsin III. (580 aa)
ENSPPAP00000020911J domain-containing protein. (148 aa)
SYT6Uncharacterized protein. (539 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
GAD2Glutamate decarboxylase 2. (580 aa)
SYPL1Synaptophysin like 1. (257 aa)
TPRG1LHSac2 domain-containing protein. (77 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
SYT4Synaptotagmin 4. (425 aa)
SYT2Synaptotagmin 2. (419 aa)
RPH3ARabphilin 3A. (694 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (832 aa)
ZNRF1Zinc and ring finger 1. (278 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSPPAP00000027450Uncharacterized protein. (77 aa)
UNC13BUncharacterized protein. (4343 aa)
SYNPRSynaptoporin. (285 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (325 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
ATP6V1E1ATPase H+ transporting V1 subunit E1. (226 aa)
BSNBassoon presynaptic cytomatrix protein. (3898 aa)
SCAMP1Secretory carrier-associated membrane protein. (414 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
C16orf70Chromosome 16 open reading frame 70. (422 aa)
SLC18A1Solute carrier family 18 member A1. (508 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SYT8Synaptotagmin 8. (387 aa)
SYN2Synapsin II. (501 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (953 aa)
CBARPCACN subunit beta associated regulatory protein. (453 aa)
RAB3BRAB3B, member RAS oncogene family. (228 aa)
BIN1Bridging integrator 1. (585 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
SYNGR1Synaptogyrin. (233 aa)
SYNGR4Synaptogyrin. (234 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (525 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
CPLX3Complexin 3. (158 aa)
RAB26Uncharacterized protein. (190 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
DMDDystrophin. (3517 aa)
AMPHAmphiphysin. (695 aa)
SYPL2Synaptophysin like 2. (272 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
SLC6A17Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
SV2CSynaptic vesicle glycoprotein 2C. (727 aa)
STX10Syntaxin 10; Belongs to the syntaxin family. (249 aa)
CLCN3Chloride channel protein. (811 aa)
ENSPPAP00000038758MARVEL domain-containing protein. (202 aa)
PRRT2Proline rich transmembrane protein 2. (393 aa)
SYT7Uncharacterized protein. (686 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
SYT9Synaptotagmin 9. (491 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
SLC9B2Solute carrier family 9 member B2. (537 aa)
ENSPPAP00000035589Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (88 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
ENSPPAP00000033799Uncharacterized protein. (195 aa)
DMXL2Dmx like 2. (3037 aa)
OTOFOtoferlin. (1996 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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