26 items (Pan paniscus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	ENSPPAP00000015877	Uncharacterized protein. (251 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (433 aa)
	LAS1L	LAS1 like, ribosome biogenesis factor. (731 aa)
	MAK16	Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
	RRP1B	Ribosomal RNA processing 1B. (747 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (712 aa)
	WDR74	WD repeat domain 74. (385 aa)
	EBNA1BP2	EBNA1 binding protein 2. (361 aa)
	RPF1	Ribosome production factor 1 homolog. (349 aa)
	ENSPPAP00000033416	Uncharacterized protein. (208 aa)
	RRP15	Ribosomal RNA processing 15 homolog. (285 aa)
	NSA2	NSA2 ribosome biogenesis factor. (260 aa)
	ENSPPAP00000040440	Uncharacterized protein. (252 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (712 aa)
	ENSPPAP00000041825	Uncharacterized protein. (372 aa)
	MRTO4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (587 aa)
	ENSPPAP00000012368	Uncharacterized protein. (225 aa)
	RRP1	Ribosomal RNA processing 1. (461 aa)
	ENSPPAP00000011414	Uncharacterized protein. (249 aa)
	ZNF622	Zinc finger protein 622. (477 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (846 aa)
	RRS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
	MDN1	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5596 aa)
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	EBNA1BP2	ENSPPAP00000040785	ENSPPAP00000030562	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1 binding protein 2.	0.987
BOP1	EIF6	ENSPPAP00000040785	ENSPPAP00000015284	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.906
BOP1	ENSPPAP00000011414	ENSPPAP00000040785	ENSPPAP00000011414	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.816
BOP1	ENSPPAP00000012368	ENSPPAP00000040785	ENSPPAP00000012368	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.816
BOP1	ENSPPAP00000015877	ENSPPAP00000040785	ENSPPAP00000015877	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.816
BOP1	ENSPPAP00000033416	ENSPPAP00000040785	ENSPPAP00000033416	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.958
BOP1	ENSPPAP00000040440	ENSPPAP00000040785	ENSPPAP00000040440	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.816
BOP1	ENSPPAP00000041825	ENSPPAP00000040785	ENSPPAP00000041825	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.991
BOP1	FTSJ3	ENSPPAP00000040785	ENSPPAP00000008144	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.977
BOP1	LAS1L	ENSPPAP00000040785	ENSPPAP00000021979	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	LAS1 like, ribosome biogenesis factor.	0.677
BOP1	MAK16	ENSPPAP00000040785	ENSPPAP00000023911	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.898
BOP1	MDN1	ENSPPAP00000040785	ENSPPAP00000001820	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	0.524
BOP1	MRTO4	ENSPPAP00000040785	ENSPPAP00000042293	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.958
BOP1	NIP7	ENSPPAP00000040785	ENSPPAP00000000145	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.925
BOP1	NOC2L	ENSPPAP00000040785	ENSPPAP00000025116	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NOC2 like nucleolar associated transcriptional repressor.	0.985
BOP1	NSA2	ENSPPAP00000040785	ENSPPAP00000039933	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NSA2 ribosome biogenesis factor.	0.816
BOP1	PES1	ENSPPAP00000040785	ENSPPAP00000013110	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.999
BOP1	RPF1	ENSPPAP00000040785	ENSPPAP00000031338	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome production factor 1 homolog.	0.937
BOP1	RRP1	ENSPPAP00000040785	ENSPPAP00000011696	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA processing 1.	0.946
BOP1	RRP15	ENSPPAP00000040785	ENSPPAP00000038787	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA processing 15 homolog.	0.826