(21 nodes) GTP-dependent protein binding network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GCHFR	GTP cyclohydrolase I feedback regulator. (84 aa)
	RASGRP4	RAS guanyl releasing protein 4. (699 aa)
	ARFIP2	ADP ribosylation factor interacting protein 2. (341 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (721 aa)
	GCH1	GTP cyclohydrolase 1. (250 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (346 aa)
	RAB34	RAB34, member RAS oncogene family. (268 aa)
	RAB38	RAB38, member RAS oncogene family. (211 aa)
	UNC13B	Uncharacterized protein. (4343 aa)
	AP3B2	AP-3 complex subunit beta. (1055 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	LOC100993131	Cell division control protein 42 homolog. (191 aa)
	AP1G1	AP-1 complex subunit gamma. (844 aa)
	CDC42	Uncharacterized protein. (191 aa)
	RAB3A	RAB3A, member RAS oncogene family. (220 aa)
	RAB32	RAB32, member RAS oncogene family. (220 aa)
	RAB3D	RAB3D, member RAS oncogene family. (219 aa)
	HPS6	Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (775 aa)
	RAB3C	RAB3C, member RAS oncogene family. (227 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	AP3B1	ENSPPAP00000016567	ENSPPAP00000032203	AP-1 complex subunit gamma.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.853
AP1G1	AP3B2	ENSPPAP00000016567	ENSPPAP00000026682	AP-1 complex subunit gamma.	AP-3 complex subunit beta.	0.844
AP1G1	DNM1L	ENSPPAP00000016567	ENSPPAP00000034330	AP-1 complex subunit gamma.	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.443
AP3B1	AP1G1	ENSPPAP00000032203	ENSPPAP00000016567	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-1 complex subunit gamma.	0.853
AP3B1	AP3B2	ENSPPAP00000032203	ENSPPAP00000026682	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit beta.	0.901
AP3B1	HPS6	ENSPPAP00000032203	ENSPPAP00000002746	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.669
AP3B2	AP1G1	ENSPPAP00000026682	ENSPPAP00000016567	AP-3 complex subunit beta.	AP-1 complex subunit gamma.	0.844
AP3B2	AP3B1	ENSPPAP00000026682	ENSPPAP00000032203	AP-3 complex subunit beta.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.901
ARFIP2	CDC42	ENSPPAP00000039585	ENSPPAP00000015981	ADP ribosylation factor interacting protein 2.	Uncharacterized protein.	0.454
ARFIP2	LOC100993131	ENSPPAP00000039585	ENSPPAP00000017950	ADP ribosylation factor interacting protein 2.	Cell division control protein 42 homolog.	0.454
CDC42	ARFIP2	ENSPPAP00000015981	ENSPPAP00000039585	Uncharacterized protein.	ADP ribosylation factor interacting protein 2.	0.454
CDC42	PARD6A	ENSPPAP00000015981	ENSPPAP00000029706	Uncharacterized protein.	Par-6 family cell polarity regulator alpha.	0.985
DNM1L	AP1G1	ENSPPAP00000034330	ENSPPAP00000016567	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-1 complex subunit gamma.	0.443
GCH1	GCHFR	ENSPPAP00000035461	ENSPPAP00000026574	GTP cyclohydrolase 1.	GTP cyclohydrolase I feedback regulator.	0.982
GCHFR	GCH1	ENSPPAP00000026574	ENSPPAP00000035461	GTP cyclohydrolase I feedback regulator.	GTP cyclohydrolase 1.	0.982
HPS6	AP3B1	ENSPPAP00000002746	ENSPPAP00000032203	Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.669
LOC100993131	ARFIP2	ENSPPAP00000017950	ENSPPAP00000039585	Cell division control protein 42 homolog.	ADP ribosylation factor interacting protein 2.	0.454
LOC100993131	PARD6A	ENSPPAP00000017950	ENSPPAP00000029706	Cell division control protein 42 homolog.	Par-6 family cell polarity regulator alpha.	0.860
MRAS	RAPGEF5	ENSPPAP00000026580	ENSPPAP00000036954	Muscle RAS oncogene homolog.	Rap guanine nucleotide exchange factor 5.	0.966
MRAS	RASGRP4	ENSPPAP00000026580	ENSPPAP00000042502	Muscle RAS oncogene homolog.	RAS guanyl releasing protein 4.	0.775