14 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SIAH1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	ENSPPAP00000017361	Uncharacterized protein. (81 aa)
	AXIN1	Axin 1. (862 aa)
	CACYBP	Calcyclin binding protein. (230 aa)
	CTNNBIP1	Catenin beta interacting protein 1. (81 aa)
	APC2	Uncharacterized protein. (1779 aa)
	CSNK1A1	Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
	ENSPPAP00000033311	Protein kinase domain-containing protein. (305 aa)
	ENSPPAP00000032500	Uncharacterized protein. (212 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (463 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	AXIN2	Axin 2. (843 aa)
	APC	APC regulator of WNT signaling pathway. (2844 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	AXIN1	ENSPPAP00000018659	ENSPPAP00000016161	APC regulator of WNT signaling pathway.	Axin 1.	0.999
APC	AXIN2	ENSPPAP00000018659	ENSPPAP00000021872	APC regulator of WNT signaling pathway.	Axin 2.	0.996
APC	CSNK1A1	ENSPPAP00000018659	ENSPPAP00000036932	APC regulator of WNT signaling pathway.	Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.	0.914
APC	CTNNB1	ENSPPAP00000018659	ENSPPAP00000024694	APC regulator of WNT signaling pathway.	Catenin beta 1.	0.999
APC	CTNNBIP1	ENSPPAP00000018659	ENSPPAP00000008602	APC regulator of WNT signaling pathway.	Catenin beta interacting protein 1.	0.802
APC	ENSPPAP00000017361	ENSPPAP00000018659	ENSPPAP00000017361	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.837
APC	ENSPPAP00000033311	ENSPPAP00000018659	ENSPPAP00000033311	APC regulator of WNT signaling pathway.	Protein kinase domain-containing protein.	0.871
APC	GSK3A	ENSPPAP00000018659	ENSPPAP00000027110	APC regulator of WNT signaling pathway.	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	0.829
APC	GSK3B	ENSPPAP00000018659	ENSPPAP00000036427	APC regulator of WNT signaling pathway.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.989
APC	SIAH1	ENSPPAP00000018659	ENSPPAP00000017098	APC regulator of WNT signaling pathway.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.696
APC2	AXIN1	ENSPPAP00000003273	ENSPPAP00000016161	Uncharacterized protein.	Axin 1.	0.926
APC2	AXIN2	ENSPPAP00000003273	ENSPPAP00000021872	Uncharacterized protein.	Axin 2.	0.852
APC2	CSNK1A1	ENSPPAP00000003273	ENSPPAP00000036932	Uncharacterized protein.	Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.	0.538
APC2	CTNNB1	ENSPPAP00000003273	ENSPPAP00000024694	Uncharacterized protein.	Catenin beta 1.	0.916
APC2	CTNNBIP1	ENSPPAP00000003273	ENSPPAP00000008602	Uncharacterized protein.	Catenin beta interacting protein 1.	0.512
APC2	ENSPPAP00000017361	ENSPPAP00000003273	ENSPPAP00000017361	Uncharacterized protein.	Uncharacterized protein.	0.538
APC2	ENSPPAP00000033311	ENSPPAP00000003273	ENSPPAP00000033311	Uncharacterized protein.	Protein kinase domain-containing protein.	0.538
APC2	GSK3A	ENSPPAP00000003273	ENSPPAP00000027110	Uncharacterized protein.	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	0.780
APC2	GSK3B	ENSPPAP00000003273	ENSPPAP00000036427	Uncharacterized protein.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.780
AXIN1	APC	ENSPPAP00000016161	ENSPPAP00000018659	Axin 1.	APC regulator of WNT signaling pathway.	0.999