(39 nodes) Positive regulation of B cell proliferation network (Pan paniscus)

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Predicted Interactions

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Your Input:
	TLR4	Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
	ATAD5	ATPase family AAA domain containing 5. (1832 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	TNFRSF4	TNF receptor superfamily member 4. (254 aa)
	FCRL3	Fc receptor like 3. (742 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (917 aa)
	ADA	Adenosine deaminase. (412 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
	TFRC	Transferrin receptor. (773 aa)
	TICAM1	RHIM domain-containing protein. (541 aa)
	IL7	Interleukin 7. (179 aa)
	TIRAP	TIR domain-containing protein. (226 aa)
	PELI1	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
	IL5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
	SLC39A10	Solute carrier family 39 member 10. (831 aa)
	NFATC2	Nuclear factor of activated T cells 2. (912 aa)
	TCF3	Transcription factor 3. (673 aa)
	CD40	CD40 molecule. (277 aa)
	MEF2C	Myocyte enhancer factor 2C. (482 aa)
	NCKAP1L	NCK associated protein 1 like. (1127 aa)
	BTK	Tyrosine-protein kinase. (693 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (164 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
	CD74	CD74 molecule. (296 aa)
	TNFRSF13C	Uncharacterized protein. (112 aa)
	SASH3	SAM and SH3 domain containing 3. (380 aa)
	CD38	CD38 molecule. (300 aa)
	CLCF1	Uncharacterized protein. (322 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	BST1	Bone marrow stromal cell antigen 1. (332 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1261 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
	EPHB2	EPH receptor B2. (1039 aa)
	GPR183	G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	MIF	Macrophage migration inhibitory factor. (115 aa)
	BCL2	BCL2 apoptosis regulator. (193 aa)
	CHRNB2	Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
	CD320	CD320 molecule. (282 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	IL2	ENSPPAP00000006331	ENSPPAP00000014571	Adenosine deaminase.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.525
ADA	PTPRC	ENSPPAP00000006331	ENSPPAP00000022461	Adenosine deaminase.	Protein tyrosine phosphatase receptor type C.	0.428
BCL2	BCL6	ENSPPAP00000017780	ENSPPAP00000011560	BCL2 apoptosis regulator.	BCL6 transcription repressor.	0.750
BCL2	BTK	ENSPPAP00000017780	ENSPPAP00000031524	BCL2 apoptosis regulator.	Tyrosine-protein kinase.	0.490
BCL2	CD38	ENSPPAP00000017780	ENSPPAP00000026576	BCL2 apoptosis regulator.	CD38 molecule.	0.610
BCL2	CD40	ENSPPAP00000017780	ENSPPAP00000033584	BCL2 apoptosis regulator.	CD40 molecule.	0.467
BCL2	CDKN1A	ENSPPAP00000017780	ENSPPAP00000029279	BCL2 apoptosis regulator.	Cyclin dependent kinase inhibitor 1A.	0.647
BCL2	IL2	ENSPPAP00000017780	ENSPPAP00000014571	BCL2 apoptosis regulator.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.633
BCL2	IL7	ENSPPAP00000017780	ENSPPAP00000001986	BCL2 apoptosis regulator.	Interleukin 7.	0.609
BCL2	PTPRC	ENSPPAP00000017780	ENSPPAP00000022461	BCL2 apoptosis regulator.	Protein tyrosine phosphatase receptor type C.	0.490
BCL2	TLR4	ENSPPAP00000017780	ENSPPAP00000016171	BCL2 apoptosis regulator.	Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...]	0.419
BCL2	TNFRSF13C	ENSPPAP00000017780	ENSPPAP00000026899	BCL2 apoptosis regulator.	Uncharacterized protein.	0.519
BCL2	TNFSF13B	ENSPPAP00000017780	ENSPPAP00000006211	BCL2 apoptosis regulator.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.515
BCL6	BCL2	ENSPPAP00000011560	ENSPPAP00000017780	BCL6 transcription repressor.	BCL2 apoptosis regulator.	0.750
BCL6	BTK	ENSPPAP00000011560	ENSPPAP00000031524	BCL6 transcription repressor.	Tyrosine-protein kinase.	0.410
BCL6	CARD11	ENSPPAP00000011560	ENSPPAP00000023842	BCL6 transcription repressor.	Caspase recruitment domain family member 11.	0.437
BCL6	CD38	ENSPPAP00000011560	ENSPPAP00000026576	BCL6 transcription repressor.	CD38 molecule.	0.568
BCL6	CDKN1A	ENSPPAP00000011560	ENSPPAP00000029279	BCL6 transcription repressor.	Cyclin dependent kinase inhibitor 1A.	0.488
BCL6	GPR183	ENSPPAP00000011560	ENSPPAP00000018809	BCL6 transcription repressor.	G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family.	0.465
BCL6	IL2	ENSPPAP00000011560	ENSPPAP00000014571	BCL6 transcription repressor.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.520