STRINGSTRING
EPO EPO CHRNA3 CHRNA3 DDX3X DDX3X INCENP INCENP BMPR1B BMPR1B ADRA2B ADRA2B EMP2 EMP2 ENSPPAP00000006455 ENSPPAP00000006455 PRRC1 PRRC1 LTF LTF ENSPPAP00000004994 ENSPPAP00000004994 DBF4 DBF4 TAOK1 TAOK1 EGFR EGFR STK11 STK11 ENSPPAP00000042813 ENSPPAP00000042813 PRLR PRLR CCL5 CCL5 CCNB1 CCNB1 PPP2R3C PPP2R3C ENSPPAP00000014328 ENSPPAP00000014328 ITGB3 ITGB3 PARK7 PARK7 BMP2 BMP2 IRGM IRGM TGFB2 TGFB2 TPX2 TPX2 GAS6 GAS6 CDK5R1 CDK5R1 MOB2 MOB2 AFAP1L2 AFAP1L2 GPRC5A GPRC5A AXIN1 AXIN1 TLR3 TLR3 TGFB1 TGFB1 ENSPPAP00000017085 ENSPPAP00000017085 GPRC5C GPRC5C PIBF1 PIBF1 ENSPPAP00000017784 ENSPPAP00000017784 ENSPPAP00000017817 ENSPPAP00000017817 ANG ANG CCNT1 CCNT1 BTC BTC MARK2 MARK2 JAK2 JAK2 HNF1A HNF1A CARD14 CARD14 P2RX7 P2RX7 BMPR2 BMPR2 RIPK3 RIPK3 IGF1 IGF1 EFNA5 EFNA5 WNT11 WNT11 LOC100982471 LOC100982471 PRNP PRNP ZFP91 ZFP91 ERCC6 ERCC6 ENSPPAP00000001306 ENSPPAP00000001306 TIRAP TIRAP LOC100968508 LOC100968508 MAS1 MAS1 TRAF2 TRAF2 EGF EGF EPGN EPGN PARP16 PARP16 PINK1 PINK1 STRADB STRADB PRKAG2 PRKAG2 DUSP19 DUSP19 PDGFB PDGFB MAPK8IP2 MAPK8IP2 STRADA STRADA NRG1 NRG1 MTCP1 MTCP1 MAP2K2 MAP2K2 PIM1 PIM1 ENSPPAP00000011964 ENSPPAP00000011964 CLSPN CLSPN CAB39L CAB39L ENSPPAP00000011278 ENSPPAP00000011278 GRM5 GRM5 MAP2K1 MAP2K1 LOC100989808 LOC100989808 LOC100996179 LOC100996179 COPS8 COPS8 INSR INSR PIK3CA PIK3CA CD24 CD24 ENSPPAP00000009855 ENSPPAP00000009855 IL18 IL18 DAXX DAXX GPRC5B GPRC5B ANGPT4 ANGPT4 TRAF4 TRAF4 MAP3K7 MAP3K7 TNFSF15 TNFSF15 STK4 STK4 IL4 IL4 SLC1A1 SLC1A1 WNT5A WNT5A GHRL GHRL PHB PHB CCNY CCNY MOB1B MOB1B MLST8 MLST8 CHI3L1 CHI3L1 CCNK CCNK PRKCD PRKCD LTK LTK MAP3K13 MAP3K13 MNAT1 MNAT1 ENSPPAP00000020922 ENSPPAP00000020922 DLG1 DLG1 CD86 CD86 ENSPPAP00000021459 ENSPPAP00000021459 CCNYL1 CCNYL1 DBF4B DBF4B RGCC RGCC TOM1L1 TOM1L1 ENSPPAP00000023302 ENSPPAP00000023302 ENSPPAP00000023305 ENSPPAP00000023305 BORA BORA ENSPPAP00000023415 ENSPPAP00000023415 AGAP2 AGAP2 ETAA1 ETAA1 SLC11A1 SLC11A1 FAM20A FAM20A CARD10 CARD10 SPRY2 SPRY2 ERBB3 ERBB3 TCL1B TCL1B WNK1 WNK1 PAK2 PAK2 ADNP ADNP LEP LEP FGF13 FGF13 IGF2 IGF2 CAMKK2 CAMKK2 STAP1 STAP1 ENSPPAP00000026005 ENSPPAP00000026005 ABL1 ABL1 ANGPT1 ANGPT1 MTOR MTOR GHR GHR CAB39 CAB39 ADRB2 ADRB2 GPRC5D GPRC5D SPDYA SPDYA CCNT2 CCNT2 ENSPPAP00000028050 ENSPPAP00000028050 PHB2 PHB2 MALT1 MALT1 MAP2K6 MAP2K6 ADCY8 ADCY8 CALM3 CALM3 CDKN1A CDKN1A DGKQ DGKQ PTK2B PTK2B ENSPPAP00000030411 ENSPPAP00000030411 ENSPPAP00000030479 ENSPPAP00000030479 NCKAP1L NCKAP1L ABI1 ABI1 CKS1B CKS1B DAB2IP DAB2IP ENSPPAP00000032343 ENSPPAP00000032343 PDGFC PDGFC ALS2 ALS2 RPLP1 RPLP1 ITGB1BP1 ITGB1BP1 ENSPPAP00000033383 ENSPPAP00000033383 CCDC88A CCDC88A HBEGF HBEGF RICTOR RICTOR BMPR1A BMPR1A IQGAP1 IQGAP1 TAOK2 TAOK2 ECT2 ECT2 IRAK1 IRAK1 ALKAL1 ALKAL1 CALCA CALCA MAP3K12 MAP3K12 SRC SRC TCL1A TCL1A MT3 MT3 MOB3A MOB3A PPIA PPIA MOB1A MOB1A FGF1 FGF1 TNFRSF10A TNFRSF10A STK3 STK3 WNK4 WNK4 DAZAP2 DAZAP2 ENSPPAP00000037381 ENSPPAP00000037381 ERBB4 ERBB4 ENSPPAP00000038350 ENSPPAP00000038350 TNFRSF10B TNFRSF10B KIF14 KIF14 UCN UCN ENSPPAP00000042214 ENSPPAP00000042214 TGFBR2 TGFBR2 ALK ALK MADD MADD OSBPL8 OSBPL8 NTF3 NTF3 ACVR2B ACVR2B TGFA TGFA DELE1 DELE1 TRAF6 TRAF6 CKS2 CKS2 MOB3B MOB3B PRKCZ PRKCZ EREG EREG CD40LG CD40LG NTRK3 NTRK3 MOB3C MOB3C AREG AREG TXN TXN FBN1 FBN1 ENSPPAP00000039229 ENSPPAP00000039229 RPTOR RPTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (520 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
INCENPInner centromere protein. (913 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ADRA2BAdrenoceptor alpha 2B. (448 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
ENSPPAP00000006455Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
PRRC1Proline rich coiled-coil 1. (462 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
ENSPPAP00000004994TNF receptor-associated factor. (475 aa)
DBF4DBF4 zinc finger. (655 aa)
TAOK1TAO kinase 1. (1001 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
ENSPPAP00000042813Prohibitin. (250 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa)
CCL5C-C motif chemokine. (91 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
ENSPPAP00000014328BRCT domain-containing protein. (581 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (814 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
IRGMImmunity related GTPase M. (195 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TPX2TPX2 microtubule nucleation factor. (782 aa)
GAS6Growth arrest specific 6. (679 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (351 aa)
MOB2MOB kinase activator 2. (268 aa)
AFAP1L2Actin filament associated protein 1 like 2. (818 aa)
GPRC5AG protein-coupled receptor class C group 5 member A. (357 aa)
AXIN1Axin 1. (862 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSPPAP00000017085Prohibitin. (177 aa)
GPRC5CG protein-coupled receptor class C group 5 member C. (487 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
ENSPPAP00000017784Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (97 aa)
ENSPPAP00000017817Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (147 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (707 aa)
BTCBetacellulin. (178 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
HNF1AHNF1 homeobox A. (662 aa)
CARD14Caspase recruitment domain family member 14. (1001 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
IGF1IlGF domain-containing protein. (196 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (188 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
PRNPMajor prion protein; Belongs to the prion family. (253 aa)
ZFP91Uncharacterized protein. (543 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1491 aa)
ENSPPAP00000001306Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (107 aa)
TIRAPTIR domain-containing protein. (226 aa)
LOC100968508Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
EPGNUncharacterized protein. (85 aa)
PARP16Poly [ADP-ribose] polymerase. (323 aa)
PINK1PTEN induced kinase 1. (554 aa)
STRADBSTE20 related adaptor beta. (419 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (692 aa)
STRADASTE20 related adaptor alpha. (403 aa)
NRG1Neuregulin 1. (645 aa)
MTCP1Mature T cell proliferation 1. (107 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa)
PIM1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (406 aa)
ENSPPAP00000011964Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa)
CLSPNClaspin. (1338 aa)
CAB39LCalcium binding protein 39 like. (337 aa)
ENSPPAP00000011278Protein kinase domain-containing protein. (351 aa)
GRM5Glutamate metabotropic receptor 5. (1195 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC100989808Prohibitin. (258 aa)
LOC100996179CYCLIN domain-containing protein. (360 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
INSRTyrosine-protein kinase receptor. (1362 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
CD24CD24 molecule. (129 aa)
ENSPPAP00000009855Thioredoxin domain-containing protein. (82 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
DAXXDeath domain associated protein. (748 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (421 aa)
ANGPT4Angiopoietin 4. (503 aa)
TRAF4TNF receptor-associated factor. (451 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TNFSF15TNF superfamily member 15. (251 aa)
STK4Serine/threonine kinase 4. (487 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
SLC1A1Amino acid transporter. (524 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
PHBProhibitin. (272 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
MOB1BMOB kinase activator 1B. (221 aa)
MLST8MTOR associated protein, LST8 homolog. (327 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (389 aa)
CCNKCyclin K; Belongs to the cyclin family. (576 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LTKTyrosine-protein kinase receptor. (864 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (986 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ENSPPAP00000020922PCI domain-containing protein. (163 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
CD86CD86 molecule. (329 aa)
ENSPPAP00000021459Cyclin N-terminal domain-containing protein. (350 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
DBF4BDBF4 zinc finger B. (615 aa)
RGCCRegulator of cell cycle. (137 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (457 aa)
ENSPPAP00000023302Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa)
ENSPPAP00000023305DJ-1_PfpI domain-containing protein. (168 aa)
BORABORA aurora kinase A activator. (634 aa)
ENSPPAP00000023415Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1021 aa)
ETAA1ETAA1 activator of ATR kinase. (898 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
FAM20AFAM20A golgi associated secretory pathway pseudokinase. (541 aa)
CARD10Caspase recruitment domain family member 10. (934 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1344 aa)
TCL1BT cell leukemia/lymphoma 1B. (128 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ADNPActivity dependent neuroprotector homeobox. (1102 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
IGF2Insulin like growth factor 2. (236 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
ENSPPAP00000026005Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ANGPT1Angiopoietin 1. (498 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
GHRGrowth hormone receptor. (641 aa)
CAB39Calcium binding protein 39. (341 aa)
ADRB2Adrenoceptor beta 2. (429 aa)
GPRC5DG protein-coupled receptor class C group 5 member D. (345 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (313 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
ENSPPAP00000028050Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (93 aa)
PHB2Prohibitin. (299 aa)
MALT1MALT1 paracaspase. (786 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
DGKQDiacylglycerol kinase. (899 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ENSPPAP00000030411Uncharacterized protein. (58 aa)
ENSPPAP00000030479Prohibitin. (194 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
ABI1Abl interactor 1. (508 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
ENSPPAP00000032343Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (88 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1657 aa)
RPLP1Ribosomal protein lateral stalk subunit P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ENSPPAP00000033383Uncharacterized protein. (138 aa)
CCDC88ACoiled-coil domain containing 88A. (1824 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1686 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
TAOK2TAO kinase 2. (1234 aa)
ECT2Epithelial cell transforming 2. (914 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
ALKAL1ALK and LTK ligand 1. (129 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
SRCTyrosine-protein kinase. (458 aa)
TCL1AT cell leukemia/lymphoma 1A. (114 aa)
MT3Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
MOB3AMOB kinase activator 3A. (217 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
MOB1AMOB kinase activator 1A. (258 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
TNFRSF10ATNF receptor superfamily member 10a. (469 aa)
STK3Serine/threonine kinase 3. (467 aa)
WNK4WNK lysine deficient protein kinase 4. (1278 aa)
DAZAP2Uncharacterized protein. (168 aa)
ENSPPAP00000037381Protein kinase domain-containing protein. (409 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
ENSPPAP00000038350Uncharacterized protein. (53 aa)
TNFRSF10BTNF receptor superfamily member 10b. (439 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
UCNUrocortin. (124 aa)
ENSPPAP00000042214Protein kinase domain-containing protein. (328 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa)
ALKTyrosine-protein kinase receptor. (1312 aa)
MADDMAP kinase activating death domain. (1636 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (881 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
TGFATransforming growth factor alpha. (181 aa)
DELE1DAP3 binding cell death enhancer 1. (530 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
MOB3BMOB kinase activator 3B. (216 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
EREGEpiregulin. (169 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
MOB3CMOB kinase activator 3C. (258 aa)
AREGEGF-like domain-containing protein. (274 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
FBN1Fibrillin 1. (2871 aa)
ENSPPAP00000039229Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (16%) [HD]