STRINGSTRING
CAVIN3 CAVIN3 PER2 PER2 TOP1 TOP1 ID3 ID3 ENSPPAP00000002562 ENSPPAP00000002562 NRIP1 NRIP1 ENSPPAP00000001242 ENSPPAP00000001242 GFPT1 GFPT1 CIART CIART ARNTL ARNTL RBM4B RBM4B LOC100980724 LOC100980724 PPP1CA PPP1CA CSNK1D CSNK1D SIRT1 SIRT1 USP2 USP2 RORC RORC PER3 PER3 LGR4 LGR4 PPP1CB PPP1CB ZPBP2 ZPBP2 CLOCK CLOCK PML PML LOC100983911 LOC100983911 EGR1 EGR1 DRD2 DRD2 PPP1CC PPP1CC ENSPPAP00000013852 ENSPPAP00000013852 HUWE1 HUWE1 RELB RELB OGT OGT NCOA2 NCOA2 ENSPPAP00000017065 ENSPPAP00000017065 PRMT5 PRMT5 NPAS2 NPAS2 HDAC1 HDAC1 ENSPPAP00000018727 ENSPPAP00000018727 BHLHE40 BHLHE40 HDAC2 HDAC2 CRY2 CRY2 MYBBP1A MYBBP1A ZFHX3 ZFHX3 SIRT6 SIRT6 ID2 ID2 LOC100975570 LOC100975570 PPARGC1A PPARGC1A BHLHE41 BHLHE41 RAI1 RAI1 NUDT12 NUDT12 ID1 ID1 HDAC3 HDAC3 MAGED1 MAGED1 KDM2A KDM2A RORA RORA HNRNPU HNRNPU KDM8 KDM8 NR0B2 NR0B2 ATF4 ATF4 PPARA PPARA NGFR NGFR ARNTL2 ARNTL2 CARTPT CARTPT PER1 PER1 ENSPPAP00000036081 ENSPPAP00000036081 KDM5A KDM5A CRY1 CRY1 MTA1 MTA1 NAMPT NAMPT MYCBP2 MYCBP2 PASD1 PASD1 NOCT NOCT NR1D1 NR1D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAVIN3Caveolae associated protein 3. (293 aa)
PER2Period circadian regulator 2. (1255 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (765 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
ENSPPAP00000001242BHLH domain-containing protein. (117 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
CIARTCircadian associated repressor of transcription. (385 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
SIRT1Sirtuin 1. (693 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
RORCRAR related orphan receptor C. (525 aa)
PER3Period circadian regulator 3. (1211 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (935 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
ZPBP2Zona pellucida binding protein 2. (338 aa)
CLOCKClock circadian regulator. (847 aa)
PMLUncharacterized protein. (836 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
ENSPPAP00000013852RRM domain-containing protein. (161 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4412 aa)
RELBRELB proto-oncogene, NF-kB subunit. (537 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1057 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
ENSPPAP00000017065SER_THR_PHOSPHATASE domain-containing protein. (297 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa)
NPAS2Neuronal PAS domain protein 2. (827 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ENSPPAP00000018727Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (486 aa)
BHLHE40Basic helix-loop-helix family member e40. (414 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (510 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
MYBBP1AMYB binding protein 1a. (1338 aa)
ZFHX3Zinc finger homeobox 3. (3607 aa)
SIRT6Sirtuin 6. (355 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
LOC100975570Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
BHLHE41Uncharacterized protein. (272 aa)
RAI1Retinoic acid induced 1. (1917 aa)
NUDT12Nudix hydrolase 12. (462 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (155 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
MAGED1MAGE family member D1. (834 aa)
KDM2ALysine demethylase 2A. (1162 aa)
RORARAR related orphan receptor A. (559 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
KDM8Lysine demethylase 8. (454 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
ATF4Activating transcription factor 4. (340 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
NGFRNerve growth factor receptor. (427 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (624 aa)
CARTPTCART prepropeptide. (116 aa)
PER1Period circadian regulator 1. (1290 aa)
ENSPPAP00000036081Uncharacterized protein. (302 aa)
KDM5ALysine demethylase 5A. (1643 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
MTA1Uncharacterized protein. (875 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (475 aa)
MYCBP2MYC binding protein 2. (4751 aa)
PASD1PAS domain containing repressor 1. (788 aa)
NOCTNocturnin. (394 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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