(21 nodes) Plasma lipoprotein particle assembly network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	APOA5	Apolipoprotein A5. (366 aa)
	PLAGL2	PLAG1 like zinc finger 2. (496 aa)
	APOB	Apolipoprotein B. (4535 aa)
	PRKACG	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
	ENSPPAP00000003657	Uncharacterized protein. (450 aa)
	APOC3	Apolipoprotein C3. (99 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family. (267 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
	APOM	Apolipoprotein M. (188 aa)
	APOE	Apolipoprotein E. (317 aa)
	DGAT1	O-acyltransferase. (505 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
	APOA4	Apolipoprotein A4. (396 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (530 aa)
	MTTP	Microsomal triglyceride transfer protein. (921 aa)
	SOAT1	O-acyltransferase. (550 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2146 aa)
	SOAT2	O-acyltransferase. (526 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSPPAP00000035173	ENSPPAP00000007656	ATP binding cassette subfamily A member 1.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	0.935
ABCA1	APOA5	ENSPPAP00000035173	ENSPPAP00000035458	ATP binding cassette subfamily A member 1.	Apolipoprotein A5.	0.467
ABCA1	APOB	ENSPPAP00000035173	ENSPPAP00000002804	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.706
ABCA1	APOC3	ENSPPAP00000035173	ENSPPAP00000003943	ATP binding cassette subfamily A member 1.	Apolipoprotein C3.	0.634
ABCA1	APOE	ENSPPAP00000035173	ENSPPAP00000022762	ATP binding cassette subfamily A member 1.	Apolipoprotein E.	0.854
ABCA1	APOM	ENSPPAP00000035173	ENSPPAP00000019117	ATP binding cassette subfamily A member 1.	Apolipoprotein M.	0.409
ABCA1	MTTP	ENSPPAP00000035173	ENSPPAP00000031074	ATP binding cassette subfamily A member 1.	Microsomal triglyceride transfer protein.	0.404
ABCA1	PRKACA	ENSPPAP00000035173	ENSPPAP00000003342	ATP binding cassette subfamily A member 1.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.470
ABCA1	PRKACB	ENSPPAP00000035173	ENSPPAP00000017680	ATP binding cassette subfamily A member 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.476
ABCA1	PRKACG	ENSPPAP00000035173	ENSPPAP00000002963	ATP binding cassette subfamily A member 1.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.470
ABCA1	SOAT1	ENSPPAP00000035173	ENSPPAP00000031689	ATP binding cassette subfamily A member 1.	O-acyltransferase.	0.478
ABCA7	APOE	ENSPPAP00000032613	ENSPPAP00000022762	ATP binding cassette subfamily A member 7.	Apolipoprotein E.	0.644
ACSL3	DGAT1	ENSPPAP00000011182	ENSPPAP00000025726	Acyl-CoA synthetase long chain family member 3.	O-acyltransferase.	0.675
ACSL3	LPCAT3	ENSPPAP00000011182	ENSPPAP00000026205	Acyl-CoA synthetase long chain family member 3.	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.	0.453
APOA1	ABCA1	ENSPPAP00000007656	ENSPPAP00000035173	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	ATP binding cassette subfamily A member 1.	0.935
APOA1	APOA4	ENSPPAP00000007656	ENSPPAP00000028262	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein A4.	0.802
APOA1	APOA5	ENSPPAP00000007656	ENSPPAP00000035458	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein A5.	0.668
APOA1	APOB	ENSPPAP00000007656	ENSPPAP00000002804	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein B.	0.820
APOA1	APOC3	ENSPPAP00000007656	ENSPPAP00000003943	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein C3.	0.731
APOA1	APOE	ENSPPAP00000007656	ENSPPAP00000022762	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein E.	0.859