Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABI1 | MLLT3 | ENSPPAP00000031713 | ENSPPAP00000007551 | Abl interactor 1. | MLLT3 super elongation complex subunit. | 0.473 |
| ALDH1A2 | TBX18 | ENSPPAP00000021109 | ENSPPAP00000011172 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. | T-box transcription factor 18. | 0.487 |
| ALDH1A2 | WT1 | ENSPPAP00000021109 | ENSPPAP00000021187 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. | Uncharacterized protein. | 0.405 |
| ATM | BMPR1A | ENSPPAP00000009058 | ENSPPAP00000033833 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.421 |
| ATM | EP300 | ENSPPAP00000009058 | ENSPPAP00000019195 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | E1A binding protein p300. | 0.691 |
| ATM | NKX3-1 | ENSPPAP00000009058 | ENSPPAP00000008388 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | NK3 homeobox 1. | 0.465 |
| ATM | PALB2 | ENSPPAP00000009058 | ENSPPAP00000005181 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Partner and localizer of BRCA2. | 0.913 |
| ATM | PRKDC | ENSPPAP00000009058 | ENSPPAP00000013799 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. | 0.830 |
| ATM | SMAD4 | ENSPPAP00000009058 | ENSPPAP00000009478 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Mothers against decapentaplegic homolog. | 0.492 |
| ATM | TP53 | ENSPPAP00000009058 | ENSPPAP00000011040 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| ATM | XRCC2 | ENSPPAP00000009058 | ENSPPAP00000020080 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | X-ray repair cross complementing 2. | 0.747 |
| AXIN2 | BMP4 | ENSPPAP00000021872 | ENSPPAP00000011018 | Axin 2. | TGF_BETA_2 domain-containing protein. | 0.461 |
| AXIN2 | BMPR1A | ENSPPAP00000021872 | ENSPPAP00000033833 | Axin 2. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.474 |
| AXIN2 | DKK1 | ENSPPAP00000021872 | ENSPPAP00000022474 | Axin 2. | Dickkopf WNT signaling pathway inhibitor 1. | 0.677 |
| AXIN2 | DVL2 | ENSPPAP00000021872 | ENSPPAP00000016217 | Axin 2. | Dishevelled segment polarity protein 2. | 0.976 |
| AXIN2 | FZD5 | ENSPPAP00000021872 | ENSPPAP00000000280 | Axin 2. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.570 |
| AXIN2 | LEF1 | ENSPPAP00000021872 | ENSPPAP00000040542 | Axin 2. | Lymphoid enhancer binding factor 1. | 0.980 |
| AXIN2 | LRP6 | ENSPPAP00000021872 | ENSPPAP00000022806 | Axin 2. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.817 |
| AXIN2 | SFRP1 | ENSPPAP00000021872 | ENSPPAP00000022366 | Axin 2. | NTR domain-containing protein. | 0.623 |
| AXIN2 | SHH | ENSPPAP00000021872 | ENSPPAP00000020557 | Axin 2. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.476 |
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