STRINGSTRING
HTT HTT PPP2R5D PPP2R5D FCRL3 FCRL3 PPP1R1B PPP1R1B ENSPPAP00000009601 ENSPPAP00000009601 ENSPPAP00000009556 ENSPPAP00000009556 CNEP1R1 CNEP1R1 ENSPPAP00000009404 ENSPPAP00000009404 ENSPPAP00000009313 ENSPPAP00000009313 PPP1R16B PPP1R16B ENSPPAP00000008364 ENSPPAP00000008364 MTMR9 MTMR9 ENSPPAP00000007967 ENSPPAP00000007967 PPP1R2C PPP1R2C ENSPPAP00000006992 ENSPPAP00000006992 AGTR2 AGTR2 PPP1R15A PPP1R15A TMEM225 TMEM225 PPP4R4 PPP4R4 ENSPPAP00000004903 ENSPPAP00000004903 JAK2 JAK2 TNF TNF TMEM130 TMEM130 ENSPPAP00000003777 ENSPPAP00000003777 RIPK3 RIPK3 PPP2R5A PPP2R5A BOD1L1 BOD1L1 LOC100994872 LOC100994872 SMG5 SMG5 LOC100982471 LOC100982471 PPP1R17 PPP1R17 LOC100968508 LOC100968508 SEMA4D SEMA4D ENSA ENSA ENSPPAP00000000414 ENSPPAP00000000414 SWAP70 SWAP70 ROCK2 ROCK2 ITGA2 ITGA2 VRK3 VRK3 PPP1R2 PPP1R2 PAWR PAWR SMG6 SMG6 SYMPK SYMPK PPP1R11 PPP1R11 IGBP1 IGBP1 NSMF NSMF MTMR2 MTMR2 SLC39A10 SLC39A10 INPP5K INPP5K ENSPPAP00000039229 ENSPPAP00000039229 PPP1R35 PPP1R35 IFNG IFNG BAG4 BAG4 BOD1L2 BOD1L2 CHP2 CHP2 TMEM225B TMEM225B GPLD1 GPLD1 EPM2A EPM2A PTPA PTPA PPIA PPIA PPP6R3 PPP6R3 SRC SRC CD300A CD300A ROCK1 ROCK1 TIPRL TIPRL PPP1R7 PPP1R7 IQGAP1 IQGAP1 MTMR4 MTMR4 MEF2C MEF2C MASTL MASTL ENSPPAP00000032795 ENSPPAP00000032795 LRRC46 LRRC46 HSP90B1 HSP90B1 NCKAP1L NCKAP1L LOC100978515 LOC100978515 MAGI2 MAGI2 ANKLE2 ANKLE2 ENSPPAP00000029777 ENSPPAP00000029777 TMEM132B TMEM132B MTMR1 MTMR1 CHP1 CHP1 CALM3 CALM3 MTMR3 MTMR3 LRRC43 LRRC43 PDGFRB PDGFRB DLC1 DLC1 ENSPPAP00000028206 ENSPPAP00000028206 PPP1R15B PPP1R15B PPP1R8 PPP1R8 PLEK PLEK CMYA5 CMYA5 CD33 CD33 YWHAB YWHAB PPP1R14D PPP1R14D PPP1R42 PPP1R42 STYXL1 STYXL1 MTOR MTOR PPP6R1 PPP6R1 ENSPPAP00000026005 ENSPPAP00000026005 ENSPPAP00000025633 ENSPPAP00000025633 CDH5 CDH5 ARPP19 ARPP19 ITGA1 ITGA1 TSC1 TSC1 LOC100977183 LOC100977183 PPARGC1B PPARGC1B FKBP1B FKBP1B MFHAS1 MFHAS1 RGN RGN PTPRC PTPRC NPNT NPNT AMBRA1 AMBRA1 IKBKB IKBKB RCAN1 RCAN1 PPP1R9B PPP1R9B SMAD3 SMAD3 CRY2 CRY2 PRKCD PRKCD LGALS3 LGALS3 BOD1 BOD1 TMEM132C TMEM132C CDCA2 CDCA2 HSP90AB1 HSP90AB1 DEF6 DEF6 LOC100971183 LOC100971183 MGAT5 MGAT5 PPP1R36 PPP1R36 ENSPPAP00000018672 ENSPPAP00000018672 LPIN1 LPIN1 PIN1 PIN1 URI1 URI1 PTBP1 PTBP1 ENSPPAP00000017817 ENSPPAP00000017817 GNAI2 GNAI2 SMG7 SMG7 TGFB1 TGFB1 SMPD1 SMPD1 SPPL3 SPPL3 NUAK1 NUAK1 PPP1R12A PPP1R12A TGFB2 TGFB2 PPP1R16A PPP1R16A BMP2 BMP2 PPP2R3C PPP2R3C YWHAE YWHAE PINK1 PINK1 PPP6R2 PPP6R2 CAMTA1 CAMTA1 ENSPPAP00000012115 ENSPPAP00000012115 GBA GBA ENSPPAP00000011964 ENSPPAP00000011964 CDK5RAP3 CDK5RAP3 ENSPPAP00000011862 ENSPPAP00000011862 ENSPPAP00000011431 ENSPPAP00000011431
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTTHuntingtin. (3053 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (668 aa)
FCRL3Fc receptor like 3. (742 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (179 aa)
ENSPPAP00000009601Uncharacterized protein; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (91 aa)
ENSPPAP00000009556Uncharacterized protein. (124 aa)
CNEP1R1CTD nuclear envelope phosphatase 1 regulatory subunit 1. (142 aa)
ENSPPAP00000009404Uncharacterized protein. (118 aa)
ENSPPAP00000009313Uncharacterized protein. (501 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (567 aa)
ENSPPAP00000008364Peptidyl-prolyl cis-trans isomerase. (155 aa)
MTMR9Myotubularin related protein 9. (549 aa)
ENSPPAP00000007967Uncharacterized protein. (341 aa)
PPP1R2CPPP1R2C family member C. (202 aa)
ENSPPAP00000006992Uncharacterized protein. (169 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (682 aa)
TMEM225Transmembrane protein 225. (225 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (873 aa)
ENSPPAP00000004903Uncharacterized protein. (305 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TMEM130Transmembrane protein 130. (435 aa)
ENSPPAP00000003777Glucosylceramidase. (342 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2968 aa)
LOC100994872Uncharacterized protein. (495 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1016 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
LOC100968508Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ENSAUncharacterized protein. (186 aa)
ENSPPAP00000000414Uncharacterized protein. (275 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
PPP1R2Protein phosphatase 1 regulatory inhibitor subunit 2. (205 aa)
PAWRPro-apoptotic WT1 regulator. (320 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1419 aa)
SYMPKSymplekin. (1310 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
IGBP1Immunoglobulin binding protein 1. (339 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (528 aa)
MTMR2Myotubularin related protein 2. (643 aa)
SLC39A10Solute carrier family 39 member 10. (831 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
ENSPPAP00000039229Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35. (227 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
BAG4BCL2 associated athanogene 4. (460 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (166 aa)
CHP2Calcineurin like EF-hand protein 2. (196 aa)
TMEM225BTransmembrane protein 225B. (221 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (850 aa)
EPM2AUncharacterized protein. (193 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (357 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (879 aa)
SRCTyrosine-protein kinase. (458 aa)
CD300ACD300a molecule. (299 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
TIPRLTOR signaling pathway regulator. (276 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7. (376 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
MASTLMicrotubule associated serine/threonine kinase like. (879 aa)
ENSPPAP0000003279514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (209 aa)
LRRC46Leucine rich repeat containing 46. (321 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
LOC10097851514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1256 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (876 aa)
ENSPPAP00000029777Uncharacterized protein; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (130 aa)
TMEM132BTransmembrane protein 132B. (1078 aa)
MTMR1Myotubularin related protein 1. (650 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
MTMR3Myotubularin related protein 3. (1199 aa)
LRRC43Leucine rich repeat containing 43. (656 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
ENSPPAP00000028206Uncharacterized protein. (147 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (713 aa)
PPP1R8Protein phosphatase 1 regulatory subunit 8. (349 aa)
PLEKPleckstrin. (350 aa)
CMYA5Cardiomyopathy associated 5. (3981 aa)
CD33CD33 molecule. (364 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PPP1R14DUncharacterized protein. (145 aa)
PPP1R42Uncharacterized protein. (347 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (313 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (881 aa)
ENSPPAP00000026005Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
ENSPPAP00000025633Uncharacterized protein. (58 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
TSC1TSC complex subunit 1. (1164 aa)
LOC100977183Uncharacterized protein. (448 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (969 aa)
RGNRegucalcin. (299 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1261 aa)
NPNTNephronectin. (612 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
RCAN1Regulator of calcineurin 1. (273 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (699 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LGALS3Galectin. (250 aa)
BOD1Biorientation of chromosomes in cell division 1. (185 aa)
TMEM132CTransmembrane protein 132C. (1079 aa)
CDCA2Cell division cycle associated 2. (1023 aa)
HSP90AB1HATPase_c domain-containing protein. (688 aa)
DEF6DEF6 guanine nucleotide exchange factor. (621 aa)
LOC100971183Uncharacterized protein. (152 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (741 aa)
PPP1R36Protein phosphatase 1 regulatory subunit 36. (422 aa)
ENSPPAP00000018672EF-hand domain-containing protein. (78 aa)
LPIN1Lipin 1. (929 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (145 aa)
URI1URI1 prefoldin like chaperone. (534 aa)
PTBP1Uncharacterized protein. (197 aa)
ENSPPAP00000017817Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa)
GNAI2G protein subunit alpha i2. (355 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1145 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SMPD1Saposin B-type domain-containing protein. (504 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
NUAK1NUAK family kinase 1. (661 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1026 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PPP1R16AProtein phosphatase 1 regulatory subunit 16A. (522 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
PINK1PTEN induced kinase 1. (554 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (966 aa)
CAMTA1Calmodulin binding transcription activator 1. (1658 aa)
ENSPPAP00000012115EF-hand domain-containing protein. (177 aa)
GBAGlucosylceramidase. (481 aa)
ENSPPAP00000011964Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (534 aa)
ENSPPAP00000011862BAG domain-containing protein. (350 aa)
ENSPPAP00000011431Uncharacterized protein. (1005 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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