STRINGSTRING
JAK2 JAK2 VRK3 VRK3 PAWR PAWR SYMPK SYMPK NSMF NSMF SLC39A10 SLC39A10 ENSPPAP00000039229 ENSPPAP00000039229 PTPA PTPA PPIA PPIA CD300A CD300A PPP1R7 PPP1R7 LRRC46 LRRC46 MAGI2 MAGI2 ANKLE2 ANKLE2 CALM3 CALM3 LRRC43 LRRC43 PDGFRB PDGFRB DLC1 DLC1 ENSPPAP00000028206 ENSPPAP00000028206 PPP1R15B PPP1R15B CD33 CD33 PPP1R14D PPP1R14D PPP1R42 PPP1R42 MTOR MTOR ENSPPAP00000026005 ENSPPAP00000026005 CDH5 CDH5 ITGA1 ITGA1 PTPRC PTPRC AMBRA1 AMBRA1 PRKCD PRKCD CDCA2 CDCA2 HSP90AB1 HSP90AB1 ENSPPAP00000018672 ENSPPAP00000018672 PIN1 PIN1 PTBP1 PTBP1 ENSPPAP00000017817 ENSPPAP00000017817 TGFB1 TGFB1 SMPD1 SMPD1 SPPL3 SPPL3 PPP1R12A PPP1R12A PINK1 PINK1 CAMTA1 CAMTA1 GBA GBA ENSPPAP00000011964 ENSPPAP00000011964 PPP2R5D PPP2R5D FCRL3 FCRL3 CNEP1R1 CNEP1R1 PPP1R16B PPP1R16B ENSPPAP00000008364 ENSPPAP00000008364 AGTR2 AGTR2 PPP1R15A PPP1R15A ENSPPAP00000004903 ENSPPAP00000004903 TMEM130 TMEM130 ENSPPAP00000003777 ENSPPAP00000003777 PPP2R5A PPP2R5A LOC100994872 LOC100994872 LOC100982471 LOC100982471 LOC100968508 LOC100968508
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK2Tyrosine-protein kinase. (1143 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
PAWRPro-apoptotic WT1 regulator. (320 aa)
SYMPKSymplekin. (1310 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (528 aa)
SLC39A10Solute carrier family 39 member 10. (831 aa)
ENSPPAP00000039229Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (357 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
CD300ACD300a molecule. (299 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7. (376 aa)
LRRC46Leucine rich repeat containing 46. (321 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1256 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (876 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
LRRC43Leucine rich repeat containing 43. (656 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
ENSPPAP00000028206Uncharacterized protein. (147 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (713 aa)
CD33CD33 molecule. (364 aa)
PPP1R14DUncharacterized protein. (145 aa)
PPP1R42Uncharacterized protein. (347 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ENSPPAP00000026005Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1261 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CDCA2Cell division cycle associated 2. (1023 aa)
HSP90AB1HATPase_c domain-containing protein. (688 aa)
ENSPPAP00000018672EF-hand domain-containing protein. (78 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (145 aa)
PTBP1Uncharacterized protein. (197 aa)
ENSPPAP00000017817Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SMPD1Saposin B-type domain-containing protein. (504 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1026 aa)
PINK1PTEN induced kinase 1. (554 aa)
CAMTA1Calmodulin binding transcription activator 1. (1658 aa)
GBAGlucosylceramidase. (481 aa)
ENSPPAP00000011964Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (668 aa)
FCRL3Fc receptor like 3. (742 aa)
CNEP1R1CTD nuclear envelope phosphatase 1 regulatory subunit 1. (142 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (567 aa)
ENSPPAP00000008364Peptidyl-prolyl cis-trans isomerase. (155 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (682 aa)
ENSPPAP00000004903Uncharacterized protein. (305 aa)
TMEM130Transmembrane protein 130. (435 aa)
ENSPPAP00000003777Glucosylceramidase. (342 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
LOC100994872Uncharacterized protein. (495 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
LOC100968508Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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