(12 nodes) SNARE complex assembly network (Pan paniscus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	UVRAG	UV radiation resistance associated. (698 aa)
	VAMP4	Vesicle associated membrane protein 4. (141 aa)
	CLTRN	Collectrin domain-containing protein. (222 aa)
	ENSPPAP00000013241	V-SNARE coiled-coil homology domain-containing protein. (201 aa)
	VAMP8	Vesicle associated membrane protein 8. (100 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	VAMP1	Vesicle associated membrane protein 1. (118 aa)
	STX1A	Syntaxin 1A; Belongs to the syntaxin family. (288 aa)
	STXBP1	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	VAMP3	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	VAMP2	V-SNARE coiled-coil homology domain-containing protein. (118 aa)
	SNCA	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPAP00000013241	STX4	ENSPPAP00000013241	ENSPPAP00000020800	V-SNARE coiled-coil homology domain-containing protein.	Syntaxin 4; Belongs to the syntaxin family.	0.849
ENSPPAP00000013241	VAMP8	ENSPPAP00000013241	ENSPPAP00000015935	V-SNARE coiled-coil homology domain-containing protein.	Vesicle associated membrane protein 8.	0.565
SNCA	STX1A	ENSPPAP00000006465	ENSPPAP00000042600	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...]	Syntaxin 1A; Belongs to the syntaxin family.	0.477
SNCA	VAMP1	ENSPPAP00000006465	ENSPPAP00000023375	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...]	Vesicle associated membrane protein 1.	0.507
SNCA	VAMP2	ENSPPAP00000006465	ENSPPAP00000005396	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...]	V-SNARE coiled-coil homology domain-containing protein.	0.783
STX1A	SNCA	ENSPPAP00000042600	ENSPPAP00000006465	Syntaxin 1A; Belongs to the syntaxin family.	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...]	0.477
STX1A	STX4	ENSPPAP00000042600	ENSPPAP00000020800	Syntaxin 1A; Belongs to the syntaxin family.	Syntaxin 4; Belongs to the syntaxin family.	0.701
STX1A	STXBP1	ENSPPAP00000042600	ENSPPAP00000002636	Syntaxin 1A; Belongs to the syntaxin family.	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.	0.999
STX1A	VAMP1	ENSPPAP00000042600	ENSPPAP00000023375	Syntaxin 1A; Belongs to the syntaxin family.	Vesicle associated membrane protein 1.	0.988
STX1A	VAMP2	ENSPPAP00000042600	ENSPPAP00000005396	Syntaxin 1A; Belongs to the syntaxin family.	V-SNARE coiled-coil homology domain-containing protein.	0.999
STX1A	VAMP3	ENSPPAP00000042600	ENSPPAP00000004128	Syntaxin 1A; Belongs to the syntaxin family.	V-SNARE coiled-coil homology domain-containing protein.	0.996
STX1A	VAMP4	ENSPPAP00000042600	ENSPPAP00000011534	Syntaxin 1A; Belongs to the syntaxin family.	Vesicle associated membrane protein 4.	0.983
STX1A	VAMP8	ENSPPAP00000042600	ENSPPAP00000015935	Syntaxin 1A; Belongs to the syntaxin family.	Vesicle associated membrane protein 8.	0.905
STX4	ENSPPAP00000013241	ENSPPAP00000020800	ENSPPAP00000013241	Syntaxin 4; Belongs to the syntaxin family.	V-SNARE coiled-coil homology domain-containing protein.	0.849
STX4	STX1A	ENSPPAP00000020800	ENSPPAP00000042600	Syntaxin 4; Belongs to the syntaxin family.	Syntaxin 1A; Belongs to the syntaxin family.	0.701
STX4	STXBP1	ENSPPAP00000020800	ENSPPAP00000002636	Syntaxin 4; Belongs to the syntaxin family.	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.	0.843
STX4	VAMP1	ENSPPAP00000020800	ENSPPAP00000023375	Syntaxin 4; Belongs to the syntaxin family.	Vesicle associated membrane protein 1.	0.987
STX4	VAMP2	ENSPPAP00000020800	ENSPPAP00000005396	Syntaxin 4; Belongs to the syntaxin family.	V-SNARE coiled-coil homology domain-containing protein.	0.998
STX4	VAMP3	ENSPPAP00000020800	ENSPPAP00000004128	Syntaxin 4; Belongs to the syntaxin family.	V-SNARE coiled-coil homology domain-containing protein.	0.999
STX4	VAMP4	ENSPPAP00000020800	ENSPPAP00000011534	Syntaxin 4; Belongs to the syntaxin family.	Vesicle associated membrane protein 4.	0.985