STRINGSTRING
ENSPPAP00000002689 ENSPPAP00000002689 IL10 IL10 VIL1 VIL1 LOC100982269 LOC100982269 HGF HGF GCLC GCLC SIRT2 SIRT2 CASR CASR APPL1 APPL1 LGMN LGMN GAB1 GAB1 MED1 MED1 APPL2 APPL2 GCLM GCLM CREB1 CREB1 NRP1 NRP1 BCAR1 BCAR1 RELA RELA ENSPPAP00000016342 ENSPPAP00000016342 TDGF1 TDGF1 CRK CRK ENSPPAP00000010058 ENSPPAP00000010058 LOC100987247 LOC100987247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPAP00000002689CFC domain-containing protein. (158 aa)
IL10Interleukin 10. (178 aa)
VIL1Villin 1. (827 aa)
LOC100982269Uncharacterized protein. (390 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (812 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
CASRCalcium sensing receptor. (1078 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
LGMNLegumain. (433 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (647 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (232 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ENSPPAP00000016342CFC domain-containing protein. (142 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSPPAP00000010058Uncharacterized protein. (165 aa)
LOC100987247CFC domain-containing protein. (170 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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