(33 nodes) Epithelial cell differentiation involved in kidney development network (Pan paniscus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	WT1	Uncharacterized protein. (429 aa)
	ENSPPAP00000024018	Uncharacterized protein. (1204 aa)
	PAX2	Paired box 2. (417 aa)
	GPR4	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
	ASXL1	ASXL transcriptional regulator 1. (1536 aa)
	CD24	CD24 molecule. (129 aa)
	MTSS1	MTSS I-BAR domain containing 1. (721 aa)
	BMP4	TGF_BETA_2 domain-containing protein. (402 aa)
	NPHS2	NPHS2 stomatin family member, podocin. (417 aa)
	KLF15	Kruppel like factor 15. (416 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	NOTCH2	Notch receptor 2. (2254 aa)
	PAX8	Paired box 8. (456 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa)
	PROM1	Prominin 1. (865 aa)
	NPHS1	NPHS1 adhesion molecule, nephrin. (1244 aa)
	PODXL	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (520 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	LAMB2	Laminin subunit beta 2. (1780 aa)
	SALL1	Spalt like transcription factor 1. (1306 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1216 aa)
	FOXJ1	Forkhead box J1. (405 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1256 aa)
	CD34	CD34 molecule. (328 aa)
	MEF2C	Myocyte enhancer factor 2C. (482 aa)
	NOTCH1	Notch receptor 1. (2573 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	SIX2	SIX homeobox 2. (291 aa)
	MYO1E	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1026 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASXL1	CD34	ENSPPAP00000009622	ENSPPAP00000031774	ASXL transcriptional regulator 1.	CD34 molecule.	0.453
ASXL1	WT1	ENSPPAP00000009622	ENSPPAP00000021187	ASXL transcriptional regulator 1.	Uncharacterized protein.	0.626
BMP4	CD34	ENSPPAP00000011018	ENSPPAP00000031774	TGF_BETA_2 domain-containing protein.	CD34 molecule.	0.565
BMP4	JAG1	ENSPPAP00000011018	ENSPPAP00000022619	TGF_BETA_2 domain-containing protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.427
BMP4	PAX2	ENSPPAP00000011018	ENSPPAP00000001193	TGF_BETA_2 domain-containing protein.	Paired box 2.	0.455
BMP4	PROM1	ENSPPAP00000011018	ENSPPAP00000019268	TGF_BETA_2 domain-containing protein.	Prominin 1.	0.504
CD24	CD34	ENSPPAP00000010029	ENSPPAP00000031774	CD24 molecule.	CD34 molecule.	0.501
CD24	NOTCH1	ENSPPAP00000010029	ENSPPAP00000033437	CD24 molecule.	Notch receptor 1.	0.457
CD24	PROM1	ENSPPAP00000010029	ENSPPAP00000019268	CD24 molecule.	Prominin 1.	0.686
CD34	ASXL1	ENSPPAP00000031774	ENSPPAP00000009622	CD34 molecule.	ASXL transcriptional regulator 1.	0.453
CD34	BMP4	ENSPPAP00000031774	ENSPPAP00000011018	CD34 molecule.	TGF_BETA_2 domain-containing protein.	0.565
CD34	CD24	ENSPPAP00000031774	ENSPPAP00000010029	CD34 molecule.	CD24 molecule.	0.501
CD34	NOTCH1	ENSPPAP00000031774	ENSPPAP00000033437	CD34 molecule.	Notch receptor 1.	0.479
CD34	PODXL	ENSPPAP00000031774	ENSPPAP00000021370	CD34 molecule.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.603
CD34	PROM1	ENSPPAP00000031774	ENSPPAP00000019268	CD34 molecule.	Prominin 1.	0.710
CD34	WT1	ENSPPAP00000031774	ENSPPAP00000021187	CD34 molecule.	Uncharacterized protein.	0.497
EDNRA	EDNRB	ENSPPAP00000029164	ENSPPAP00000008765	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.984
EDNRB	EDNRA	ENSPPAP00000008765	ENSPPAP00000029164	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.984
ENSPPAP00000024018	PAX2	ENSPPAP00000024018	ENSPPAP00000001193	Uncharacterized protein.	Paired box 2.	0.459
ENSPPAP00000024018	SIX2	ENSPPAP00000024018	ENSPPAP00000035137	Uncharacterized protein.	SIX homeobox 2.	0.566