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DNAAF2 DNAAF2 C16orf71 C16orf71 CCDC63 CCDC63 PIH1D3 PIH1D3 LRRC49 LRRC49 DNAL1 DNAL1 DNAI1 DNAI1 DNAH8 DNAH8 CCDC151 CCDC151 CCDC103 CCDC103 DNAAF4 DNAAF4 ARMC4 ARMC4 DNAAF1 DNAAF1 DNAAF5 DNAAF5 LRRC6 LRRC6 ZMYND10 ZMYND10 TTC25 TTC25 EFCAB1 EFCAB1 DNAH17 DNAH17 DAW1 DAW1 CCDC114 CCDC114 DNAH5 DNAH5 DNAI2 DNAI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (813 aa)
C16orf71Chromosome 16 open reading frame 71. (520 aa)
CCDC63Coiled-coil domain containing 63. (562 aa)
PIH1D3PIH1 domain containing 3. (214 aa)
LRRC49Leucine rich repeat containing 49. (686 aa)
DNAL1Dynein axonemal light chain 1. (190 aa)
DNAI1Dynein axonemal intermediate chain 1. (699 aa)
DNAH8Dynein axonemal heavy chain 8. (4707 aa)
CCDC151Coiled-coil domain containing 151. (596 aa)
CCDC103Coiled-coil domain containing 103. (242 aa)
DNAAF4Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility (By similarity). (420 aa)
ARMC4Armadillo repeat containing 4. (1004 aa)
DNAAF1Dynein assembly factor 1, axonemal. (616 aa)
DNAAF5Dynein axonemal assembly factor 5. (703 aa)
LRRC6Leucine rich repeat containing 6. (463 aa)
ZMYND10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
TTC25Tetratricopeptide repeat domain 25. (671 aa)
EFCAB1EF-hand calcium binding domain 1. (211 aa)
DNAH17Dynein axonemal heavy chain 17. (4461 aa)
DAW1Dynein assembly factor with WD repeats 1. (417 aa)
CCDC114Coiled-coil domain containing 114. (670 aa)
DNAH5Dynein axonemal heavy chain 5. (4446 aa)
DNAI2Dynein axonemal intermediate chain 2. (605 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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