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| | GAPT | GRB2 binding adaptor protein, transmembrane. (157 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (150 aa) |
| | ADA | Adenosine deaminase. (412 aa) |
| | IFNW1 | Interferon omega 1. (200 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) |
| | SYVN1 | Synoviolin 1. (625 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa) |
| | NFAM1 | NFAT activating protein with ITAM motif 1. (270 aa) |
| | IFNA2 | Interferon alpha 2. (170 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa) |
| | DOCK10 | Dedicator of cytokinesis 10; Belongs to the DOCK family. (2187 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1101 aa) |
| | TICAM1 | RHIM domain-containing protein. (541 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | IFNE | Interferon epsilon. (208 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (715 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | IFNA10 | Interferon alpha 10. (189 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | IL7 | Interleukin 7. (179 aa) |
| | LOC100972005 | Uncharacterized protein. (198 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | LFNG | Uncharacterized protein. (306 aa) |
| | IFNA6 | Interferon alpha 6. (189 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | IFNA17 | Interferon alpha 17. (189 aa) |
| | ENSPPAP00000001268 | DHR-2 domain-containing protein; Belongs to the DOCK family. (503 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | TXLNA | Taxilin alpha. (546 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (585 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (570 aa) |
| | ITM2A | Integral membrane protein 2A. (263 aa) |
| | CHRNB2 | Cholinergic receptor nicotinic beta 2 subunit. (502 aa) |
| | IL9 | Interleukin 9. (144 aa) |
| | ENSPPAP00000017085 | Prohibitin. (177 aa) |
| | ENSPPAP00000016834 | Uncharacterized protein. (195 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9. (223 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | IRF8 | Interferon regulatory factor 8. (426 aa) |
| | BST2 | Uncharacterized protein. (185 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | SKAP2 | Src kinase associated phosphoprotein 2. (359 aa) |
| | AKAP17A | A-kinase anchoring protein 17A. (683 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1832 aa) |
| | GON4L | Gon-4 like. (2226 aa) |
| | NOTCH2 | Notch receptor 2. (2254 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | CXCR5 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | CLCF1 | Uncharacterized protein. (322 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | LAT2 | Linker for activation of T cells family member 2. (243 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | CMTM7 | MARVEL domain-containing protein. (140 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1261 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | SHB | SH2 domain-containing protein. (285 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | ENSPPAP00000020322 | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (320 aa) |
| | IFNA21 | Interferon alpha 21. (189 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (621 aa) |
| | IFNA7 | Interferon alpha 7. (189 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | EPHB2 | EPH receptor B2. (1039 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | ENSPPAP00000019366 | Uncharacterized protein. (154 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (485 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1108 aa) |
| | BCL2 | BCL2 apoptosis regulator. (193 aa) |
| | PAX5 | Paired box 5. (337 aa) |
| | NKX2-3 | Homeobox domain-containing protein. (303 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | HHEX | Hematopoietically expressed homeobox. (255 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | CDH17 | Cadherin 17. (809 aa) |
| | CD38 | CD38 molecule. (300 aa) |
| | YY1 | Uncharacterized protein. (370 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | LAX1 | Lymphocyte transmembrane adaptor 1. (398 aa) |
| | STAT6 | Signal transducer and activator of transcription. (852 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) |
| | ENSPPAP00000026779 | Uncharacterized protein. (720 aa) |
| | ONECUT1 | One cut domain family member. (402 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (447 aa) |
| | ICOSLG | Uncharacterized protein. (463 aa) |
| | CD70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (193 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (573 aa) |
| | PTEN | Uncharacterized protein. (542 aa) |
| | ENSPPAP00000011925 | Uncharacterized protein. (383 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | CD19 | CD19 molecule. (545 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | LOC100989808 | Prohibitin. (258 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (517 aa) |
| | C17orf99 | Chromosome 17 open reading frame 99. (265 aa) |
| | SPI1 | Spi-1 proto-oncogene. (271 aa) |
| | RABL3 | RAB, member of RAS oncogene family like 3. (255 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | MALT1 | MALT1 paracaspase. (786 aa) |
| | CD22 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa) |
| | LOC100981967 | Uncharacterized protein. (278 aa) |
| | ENSPPAP00000028953 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (264 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1313 aa) |
| | KIAA1841 | KIAA1841. (718 aa) |
| | LGALS1 | Galectin. (135 aa) |
| | ADGRG3 | Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (549 aa) |
| | CD180 | CD180 molecule. (661 aa) |
| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase. (321 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | LOC100984838 | Uncharacterized protein. (334 aa) |
| | BCL3 | BCL3 transcription coactivator. (383 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | AICDA | Activation induced cytidine deaminase. (199 aa) |
| | ENSPPAP00000030479 | Prohibitin. (194 aa) |
| | MS4A1 | Membrane spanning 4-domains A1. (297 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | EXO1 | Exonuclease 1. (846 aa) |
| | CD79A | CD79a molecule. (226 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (424 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | BANK1 | B cell scaffold protein with ankyrin repeats 1. (770 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (598 aa) |
| | ENSPPAP00000032591 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (288 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (843 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (661 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (482 aa) |
| | LOC100995377 | Uncharacterized protein. (557 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa) |
| | STAT5B | Signal transducer and activator of transcription. (789 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (218 aa) |
| | IL11 | Interleukin 11. (199 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1166 aa) |
| | KLF6 | Kruppel like factor 6. (298 aa) |
| | XRCC4 | X-ray repair cross complementing 4. (334 aa) |
| | BLNK | B cell linker. (417 aa) |
| | TCF3 | Transcription factor 3. (673 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) |
| | ENSPPAP00000036378 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (279 aa) |
| | JAK3 | Tyrosine-protein kinase. (1090 aa) |
| | CD79B | CD79b molecule. (229 aa) |
| | ZBTB7A | Uncharacterized protein. (509 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 2. (264 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1304 aa) |
| | YY1AP1 | YY1 associated protein 1. (892 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (499 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (736 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (590 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | TBC1D10C | TBC1 domain family member 10C. (446 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1058 aa) |
| | LOC100975678 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (566 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | ENSPPAP00000042813 | Prohibitin. (250 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa) |
| | SP3 | Sp3 transcription factor. (721 aa) |
| | PIK3R2 | Uncharacterized protein. (663 aa) |
| | FOXP3 | Forkhead box P3. (441 aa) |
| | LYL1 | LYL1 basic helix-loop-helix family member. (233 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1507 aa) |
| | DOCK11 | Dedicator of cytokinesis 11; Belongs to the DOCK family. (2073 aa) |
| | POU2AF1 | POU class 2 homeobox associating factor 1. (256 aa) |
| | ENSPPAP00000007855 | Uncharacterized protein. (192 aa) |
| | PHB | Prohibitin. (272 aa) |
| | CR2 | Complement C3d receptor 2. (969 aa) |
