STRINGSTRING
ENSPPAP00000021143 ENSPPAP00000021143 INSIG2 INSIG2 CEACAM1 CEACAM1 LPGAT1 LPGAT1 RGN RGN ERLIN2 ERLIN2 ERLIN1 ERLIN1 ACADL ACADL ELOVL5 ELOVL5 INSIG1 INSIG1 APOA4 APOA4 CD74 CD74 MLXIPL MLXIPL ABCD1 ABCD1 NR1H3 NR1H3 ACADVL ACADVL IL1B IL1B APOA5 APOA5 APOC2 APOC2 SLC45A3 SLC45A3 PDK4 PDK4 NR1H2 NR1H2 AVP AVP TRIB3 TRIB3 PLA2G3 PLA2G3 GIP GIP PTGS2 PTGS2 CYP7A1 CYP7A1 MID1IP1 MID1IP1 SCAP SCAP FABP5 FABP5 APOC3 APOC3 SIRT1 SIRT1 AVPR1A AVPR1A ANXA1 ANXA1 ABCD2 ABCD2 ENSPPAP00000015127 ENSPPAP00000015127 EIF6 EIF6 WDTC1 WDTC1 BRCA1 BRCA1 PIBF1 PIBF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPAP00000021143Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (125 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
CEACAM1Uncharacterized protein. (464 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (370 aa)
RGNRegucalcin. (299 aa)
ERLIN2ER lipid raft associated 2. (339 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ELOVL5Elongation of very long chain fatty acids protein. (326 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
APOA4Apolipoprotein A4. (396 aa)
CD74CD74 molecule. (296 aa)
MLXIPLMLX interacting protein like. (852 aa)
ABCD1ATP binding cassette subfamily D member 1. (745 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (677 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
APOA5Apolipoprotein A5. (366 aa)
APOC2Uncharacterized protein. (178 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
AVPUncharacterized protein; Belongs to the vasopressin/oxytocin family. (134 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
GIPUncharacterized protein. (94 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
MID1IP1MID1 interacting protein 1. (183 aa)
SCAPSREBF chaperone. (1269 aa)
FABP5Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
APOC3Apolipoprotein C3. (99 aa)
SIRT1Sirtuin 1. (693 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
ANXA1Annexin. (346 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
ENSPPAP00000015127FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (130 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
WDTC1WD and tetratricopeptide repeats 1. (776 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1849 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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