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| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | LOC100981047 | Shisa family member 5. (137 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (297 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (439 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | TIFA | Uncharacterized protein. (89 aa) |
| | OTUD7A | OTU domain-containing protein. (755 aa) |
| | IFIT5 | Interferon induced protein with tetratricopeptide repeats 5. (482 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | UBD | Ubiquitin D. (165 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) |
| | TIRAP | TIR domain-containing protein. (226 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | NFKBIB | ANK_REP_REGION domain-containing protein. (270 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | TICAM1 | RHIM domain-containing protein. (541 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | CC2D1A | Uncharacterized protein. (700 aa) |
| | S100A4 | Protein S100; Belongs to the S-100 family. (101 aa) |
| | TNIP3 | TNFAIP3 interacting protein 3. (376 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | FLNA | Uncharacterized protein. (2188 aa) |
| | NUP62 | Nsp1_C domain-containing protein. (419 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (229 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | NLRX1 | NLR family member X1. (975 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | EEF1D | Eukaryotic translation elongation factor 1 delta; Belongs to the EF-1-beta/EF-1-delta family. (692 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (711 aa) |
| | DHX36 | DEAH-box helicase 36. (1009 aa) |
| | TFRC | Transferrin receptor. (773 aa) |
| | VAPA | VAMP associated protein A. (267 aa) |
| | ALPK1 | Alpha kinase 1. (1246 aa) |
| | ENSPPAP00000004994 | TNF receptor-associated factor. (475 aa) |
| | S100A13 | S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa) |
| | SHISA5 | Shisa family member 5. (247 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (397 aa) |
| | CXXC5 | CXXC finger protein 5. (322 aa) |
| | UBE2V1-2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | EDAR | Ectodysplasin A receptor. (496 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | TNIP1 | TNFAIP3 interacting protein 1. (645 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | SIRT1 | Sirtuin 1. (693 aa) |
| | USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (540 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (200 aa) |
| | ENSPPAP00000007509 | Helicase C-terminal domain-containing protein. (317 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (482 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa) |
| | SLC35B2 | Solute carrier family 35 member B2. (432 aa) |
| | OTUD7B | OTU deubiquitinase 7B. (841 aa) |
| | DDX1 | DEAD-box helicase 1. (740 aa) |
| | BRD4 | Bromodomain containing 4. (1325 aa) |
| | C18orf32 | Chromosome 18 open reading frame 32. (76 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (619 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (805 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | TRAF4 | TNF receptor-associated factor. (451 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | GPRC5B | G protein-coupled receptor class C group 5 member B. (421 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (710 aa) |
| | UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) |
| | CLEC6A | C-type lectin domain containing 6A. (208 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | SLC20A1 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (679 aa) |
| | ENSPPAP00000011278 | Protein kinase domain-containing protein. (351 aa) |
| | INAVA | Innate immunity activator. (663 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (1005 aa) |
| | TMEM9B | TMEM9 domain family member B. (198 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (573 aa) |
| | MTDH | Metadherin. (567 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | CANT1 | Calcium activated nucleotidase 1. (401 aa) |
| | PINK1 | PTEN induced kinase 1. (554 aa) |
| | ZDHHC17 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa) |
| | CTH | Cystathionine gamma-lyase. (439 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (403 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | JMJD8 | Jumonji domain containing 8. (270 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | RIOK3 | Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (603 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (892 aa) |
| | DHX15 | DEAH-box helicase 15. (773 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | TRIM59 | Uncharacterized protein. (333 aa) |
| | PPM1N | PP2C_C domain-containing protein. (130 aa) |
| | TRIM8 | Tripartite motif containing 8. (446 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | S100B | S_100 domain-containing protein; Belongs to the S-100 family. (94 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | LURAP1L | Leucine rich adaptor protein 1 like. (228 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | TNFRSF19 | TNF receptor superfamily member 19. (417 aa) |
| | AJUBA | Ajuba LIM protein. (538 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | NDFIP2 | Nedd4 family interacting protein 2. (336 aa) |
| | GOLT1B | Golgi transport 1B. (138 aa) |
| | ECM1 | Extracellular matrix protein 1. (540 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (352 aa) |
| | ASH1L | ASH1 like histone lysine methyltransferase. (2923 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (983 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | WLS | Wnt ligand secretion mediator. (541 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | TRIM52 | Tripartite motif-containing protein 52. (293 aa) |
| | ENSPPAP00000021176 | Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (259 aa) |
| | ENSPPAP00000021369 | Helicase C-terminal domain-containing protein. (339 aa) |
| | CARD19 | Caspase recruitment domain family member 19. (183 aa) |
| | LURAP1 | Leucine rich adaptor protein 1. (239 aa) |
| | SPHK2 | Sphingosine kinase 2. (663 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (1112 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (784 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (428 aa) |
| | CD4 | CD4 molecule. (458 aa) |
| | FADD | Death domain-containing protein. (144 aa) |
| | TMED4 | Transmembrane p24 trafficking protein 4. (227 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | BST2 | Uncharacterized protein. (185 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | ENSPPAP00000024044 | PPM-type phosphatase domain-containing protein. (75 aa) |
| | TNIP2 | CCHC NOA-type domain-containing protein. (322 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (655 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa) |
| | PPP5D1 | PPP5 tetratricopeptide repeat domain containing 1. (171 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | TMEM106A | Transmembrane protein 106A. (262 aa) |
| | LOC100975396 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (436 aa) |
| | IRF3 | Interferon regulatory factor 3. (452 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | TRIM68 | Tripartite motif containing 68. (485 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1074 aa) |
| | MIER1 | MIER1 transcriptional regulator. (565 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | SECTM1 | Secreted and transmembrane 1. (248 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | DDX21 | DExD-box helicase 21. (783 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (387 aa) |
| | TRIML1 | Tripartite motif family like 1. (468 aa) |
| | ENSPPAP00000027817 | Uncharacterized protein. (56 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (779 aa) |
| | EDA | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (223 aa) |
| | LTBR | Lymphotoxin beta receptor. (435 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | MALT1 | MALT1 paracaspase. (786 aa) |
| | CD74 | CD74 molecule. (296 aa) |
| | TFG | Trafficking from ER to golgi regulator. (400 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | ANKRD17 | Ankyrin repeat domain 17. (2602 aa) |
| | LIME1 | Uncharacterized protein. (291 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | LGALS1 | Galectin. (135 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | CLEC4D | C-type lectin domain family 4 member D. (215 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | RORA | RAR related orphan receptor A. (559 aa) |
| | TSPAN6 | Tetraspanin. (245 aa) |
| | OPTN | Optineurin. (577 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (503 aa) |
| | WDR83 | WD repeat domain 83. (315 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | DAB2IP | DAB2 interacting protein. (1155 aa) |
| | BCL10 | CARD domain-containing protein. (316 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | SLC44A2 | Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (711 aa) |
| | CCDC22 | Coiled-coil domain containing 22. (627 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | ENSPPAP00000033668 | Uncharacterized protein. (85 aa) |
| | TRIM13 | Tripartite motif containing 13. (410 aa) |
| | STAT1 | Signal transducer and activator of transcription. (759 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2813 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (335 aa) |
| | ECT2 | Epithelial cell transforming 2. (914 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | PELI2 | Pellino E3 ubiquitin protein ligase family member 2. (394 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | MIB2 | Mindbomb E3 ubiquitin protein ligase 2. (955 aa) |
| | ENSPPAP00000035541 | CCHC NOA-type domain-containing protein. (372 aa) |
| | LILRB4 | Leukocyte immunoglobulin like receptor B4. (408 aa) |
| | TRIM39 | Tripartite motif containing 39. (518 aa) |
| | DDX50 | DExD-box helicase 50. (737 aa) |
| | PER1 | Period circadian regulator 1. (1290 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | PIM2 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa) |
| | TRIML2 | Tripartite motif family like 2. (437 aa) |
| | UNC5CL | Unc-5 family C-terminal like. (518 aa) |
| | MID2 | Midline 2. (733 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | TMEM101 | Transmembrane protein 101. (257 aa) |
| | NEK6 | NIMA related kinase 6. (373 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (523 aa) |
| | ZMYND11 | Zinc finger MYND-type containing 11. (648 aa) |
| | LOC100987671 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) |
| | CASP1-2 | CARD domain-containing protein. (95 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | ENSPPAP00000040700 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | CARD8 | Caspase recruitment domain family member 8. (537 aa) |
| | GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | TERF2IP | TERF2 interacting protein. (394 aa) |
| | UFL1 | UFM1 specific ligase 1. (778 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | LOC103782663 | Uncharacterized protein. (841 aa) |
| | LITAF | Lipopolysaccharide induced TNF factor. (161 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (286 aa) |
| | PPM1B | Protein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | ZDHHC13 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (622 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
