STRINGSTRING
ATP2B1 ATP2B1 ARC ARC UCN UCN ABAT ABAT AMIGO1 AMIGO1 KCNE2 KCNE2 TRPC1 TRPC1 DNM2 DNM2 LILRA5 LILRA5 ENSPPAP00000001488 ENSPPAP00000001488 PPP3CB PPP3CB KCNC1 KCNC1 APLNR APLNR BDKRB1 BDKRB1 SLC38A3 SLC38A3 AMIGO3 AMIGO3 KCNJ2 KCNJ2 CCR2 CCR2 LOC100982471 LOC100982471 ENSPPAP00000002562 ENSPPAP00000002562 STXBP1 STXBP1 CACNB3 CACNB3 TSPO TSPO SLC9A3R1 SLC9A3R1 DRD1 DRD1 KCNA1 KCNA1 FLNA FLNA P2RX7 P2RX7 PRSS8 PRSS8 GCG GCG CHRM1 CHRM1 LOC100980724 LOC100980724 ARL6IP1 ARL6IP1 COA8 COA8 ANTKMT ANTKMT PLP1 PLP1 SRI SRI ENSPPAP00000005391 ENSPPAP00000005391 TNFRSF11A TNFRSF11A P2RY6 P2RY6 PTAFR PTAFR CACNG2 CACNG2 CCR1 CCR1 SNCA SNCA KCNE5 KCNE5 AKAP5 AKAP5 P2RY1 P2RY1 IFNGR2 IFNGR2 CALCR CALCR CYP4F2 CYP4F2 LOC103786316 LOC103786316 CRACR2A CRACR2A AVPR1A AVPR1A CACNA2D1 CACNA2D1 FFAR1 FFAR1 ABCC8 ABCC8 ENSPPAP00000007382 ENSPPAP00000007382 LRRC26 LRRC26 SLC12A2 SLC12A2 ENSPPAP00000007855 ENSPPAP00000007855 FXYD1 FXYD1 AHCYL1 AHCYL1 LRRC38 LRRC38 R3HDM1 R3HDM1 PKP2 PKP2 ORAI1 ORAI1 WNK3 WNK3 HAP1 HAP1 ENSPPAP00000009926 ENSPPAP00000009926 KIF5B KIF5B STRIT1 STRIT1 CACNB4 CACNB4 PLA2G6 PLA2G6 TRPC6 TRPC6 PDZK1 PDZK1 SNX4 SNX4 LILRA2 LILRA2 RAB3GAP1 RAB3GAP1 ENSPPAP00000011278 ENSPPAP00000011278 AVP AVP CD19 CD19 NLGN3 NLGN3 HTT HTT ATP2C2 ATP2C2 TACR2 TACR2 ADCYAP1R1 ADCYAP1R1 ENSPPAP00000012115 ENSPPAP00000012115 SYT1 SYT1 GSTO1 GSTO1 STC1 STC1 KCNIP2 KCNIP2 KCNN4 KCNN4 PLA2G3 PLA2G3 BAK1 BAK1 CLTRN CLTRN PDGFB PDGFB LOC100983911 LOC100983911 MYLK MYLK HCRT HCRT SLC6A4 SLC6A4 DRD2 DRD2 EDN1 EDN1 JPH2 JPH2 PINK1 PINK1 LOC100987645 LOC100987645 G6PD G6PD THY1 THY1 CTSS CTSS LRRC55 LRRC55 GAL GAL F2RL3 F2RL3 STAC2 STAC2 KMO KMO CACNG4 CACNG4 SLC34A1 SLC34A1 GRIN1 GRIN1 NKX2-5 NKX2-5 GALR2 GALR2 VAMP8 VAMP8 PKD2 PKD2 P2RX2 P2RX2 PTGES PTGES STIM2 STIM2 CXCL11 CXCL11 P2RX1 P2RX1 RNF207 RNF207 STK39 STK39 VMP1 VMP1 CHRNB2 CHRNB2 PLCG1 PLCG1 LHCGR LHCGR SCN3B SCN3B RGS7 RGS7 MIF MIF CASQ1 CASQ1 STAC3 STAC3 ADORA2A ADORA2A HOMER1 HOMER1 IL1A IL1A ENSPPAP00000018672 ENSPPAP00000018672 VAMP7 VAMP7 ABCB11 ABCB11 CACNB2 CACNB2 ENSPPAP00000019421 ENSPPAP00000019421 EPHB2 EPHB2 ACTN2 ACTN2 CCL2 CCL2 GNAS-2 GNAS-2 TRPC3 TRPC3 LGALS3 LGALS3 IAPP IAPP DLG1 DLG1 SPHK2 SPHK2 CREB3 CREB3 R3HDM2 R3HDM2 CAPN3 CAPN3 ENSPPAP00000022875 ENSPPAP00000022875 RGN RGN RELN RELN ENSPPAP00000023150 ENSPPAP00000023150 PPP3CC PPP3CC FHL1 FHL1 CDK5 CDK5 F2R F2R TNFSF11 TNFSF11 CNTN1 CNTN1 SYT4 SYT4 FGF12 FGF12 EHD3 EHD3 KCNQ1 KCNQ1 WNK1 WNK1 EDN3 EDN3 ATP1B2 ATP1B2 AKAP9 AKAP9 ABCB1 ABCB1 CASR CASR ABL1 ABL1 ATP1B1 ATP1B1 AVPR1B AVPR1B ANO6 ANO6 ASPH ASPH CX3CL1 CX3CL1 PLA2G1B PLA2G1B ADRB2 ADRB2 AKAP6 AKAP6 CAV1 CAV1 SCN5A SCN5A ATP2A1 ATP2A1 GRM6 GRM6 SSTR4 SSTR4 HSPA2 HSPA2 MAP2K6 MAP2K6 GPD1L GPD1L PDGFRB PDGFRB NPPA NPPA EDNRA EDNRA CALM3 CALM3 CHP1 CHP1 P2RX3 P2RX3 SCN4B SCN4B ACE2 ACE2 ANK2 ANK2 CXCL10 CXCL10 MS4A1 MS4A1 ENSPPAP00000030781 ENSPPAP00000030781 KCNMB1 KCNMB1 DTNBP1 DTNBP1 PSEN1 PSEN1 ITGB1 ITGB1 WFS1 WFS1 STIM1 STIM1 PLA2R1 PLA2R1 ATP1B3 ATP1B3 LOC100970363 LOC100970363 LOC100990946 LOC100990946 CEMIP CEMIP ARRB2 ARRB2 ENSPPAP00000033087 ENSPPAP00000033087 ATF4 ATF4 SUMO1 SUMO1 CXCL9 CXCL9 PLCG2 PLCG2 AKAP7 AKAP7 BAX BAX STAC STAC ANK3 ANK3 LOC100995958 LOC100995958 KCNC2 KCNC2 CASK CASK IL1B IL1B AKT1 AKT1 KCNK3 KCNK3 TRPV2 TRPV2 CFTR CFTR ACTN4 ACTN4 CXCL12 CXCL12 JAK3 JAK3 TREM2 TREM2 WNK4 WNK4 TRH TRH WNK2 WNK2 LOC106634824 LOC106634824 CHP2 CHP2 F2 F2 RAMP3 RAMP3 TOR2A TOR2A SLC17A8 SLC17A8 NOS1AP NOS1AP GIMAP1 GIMAP1 P2RX4 P2RX4 CAMK2A CAMK2A ATPSCKMT ATPSCKMT CXCR3 CXCR3 LRRC52 LRRC52 P2RX5 P2RX5 DMD DMD PPP3CA PPP3CA TCAF1 TCAF1 SLC6A1 SLC6A1 GABBR1 GABBR1 TRPV3 TRPV3 NTSR1 NTSR1 PLA2G4A PLA2G4A ENSPPAP00000041551 ENSPPAP00000041551 LACRT LACRT TESC TESC GLRX GLRX NPSR1 NPSR1 ENSPPAP00000042341 ENSPPAP00000042341 CACNA1D CACNA1D SLC9A1 SLC9A1 NIPSNAP2 NIPSNAP2 CCL5 CCL5 NOS1 NOS1 RYR2 RYR2 MLLT6 MLLT6 RAB3B RAB3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
UCNUrocortin. (124 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (785 aa)
LILRA5Leukocyte immunoglobulin like receptor A5. (299 aa)
ENSPPAP00000001488AKAP7_NLS domain-containing protein. (344 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (584 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
BDKRB1G_PROTEIN_RECEP_F1_2 domain-containing protein. (284 aa)
SLC38A3Solute carrier family 38 member 3. (504 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (504 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (488 aa)
TSPOTranslocator protein. (169 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
FLNAUncharacterized protein. (2188 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (343 aa)
GCGGlucagon. (179 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
ARL6IP1Uncharacterized protein. (203 aa)
COA8Cytochrome c oxidase assembly factor 8. (205 aa)
ANTKMTAdenine nucleotide translocase lysine methyltransferase. (229 aa)
PLP1Proteolipid protein 1. (277 aa)
SRISorcin. (195 aa)
ENSPPAP00000005391Rad60-SLD domain-containing protein. (84 aa)
TNFRSF11ATNF receptor superfamily member 11a. (615 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
IFNGR2Interferon gamma receptor 2. (347 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
CYP4F2Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family. (520 aa)
LOC103786316FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
CRACR2ACalcium release activated channel regulator 2A. (732 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
ENSPPAP00000007382Uncharacterized protein. (283 aa)
LRRC26Leucine rich repeat containing 26. (341 aa)
SLC12A2Solute carrier family 12 member 2. (1091 aa)
ENSPPAP00000007855Uncharacterized protein. (192 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (81 aa)
AHCYL1AdoHcyase_NAD domain-containing protein. (280 aa)
LRRC38Leucine rich repeat containing 38. (247 aa)
R3HDM1R3H domain containing 1. (1102 aa)
PKP2Plakophilin 2. (862 aa)
ORAI1Uncharacterized protein. (238 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
HAP1Huntingtin associated protein 1. (669 aa)
ENSPPAP00000009926EF-hand domain-containing protein. (85 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
PDZK1PDZ domain containing 1. (519 aa)
SNX4Sorting nexin 4. (450 aa)
LILRA2Leukocyte immunoglobulin like receptor A2. (483 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (988 aa)
ENSPPAP00000011278Protein kinase domain-containing protein. (351 aa)
AVPUncharacterized protein; Belongs to the vasopressin/oxytocin family. (134 aa)
CD19CD19 molecule. (545 aa)
NLGN3Neuroligin 3. (848 aa)
HTTHuntingtin. (3053 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (517 aa)
ENSPPAP00000012115EF-hand domain-containing protein. (177 aa)
SYT1Synaptotagmin 1. (422 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
STC1Stanniocalcin 1. (247 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CLTRNCollectrin domain-containing protein. (222 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
MYLKMyosin light chain kinase. (1847 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
EDN1Endothelin 1. (212 aa)
JPH2Uncharacterized protein. (129 aa)
PINK1PTEN induced kinase 1. (554 aa)
LOC100987645Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
THY1Thy-1 cell surface antigen. (161 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
LRRC55Leucine rich repeat containing 55. (341 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (492 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (339 aa)
SLC34A1Solute carrier family 34 member 1. (641 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
NKX2-5NK2 homeobox 5. (325 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (788 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (405 aa)
PTGESProstaglandin E synthase. (152 aa)
STIM2Stromal interaction molecule 2. (912 aa)
CXCL11C-X-C motif chemokine. (94 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
RNF207Ring finger protein 207. (634 aa)
STK39Serine/threonine kinase 39. (499 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
RGS7Regulator of G protein signaling 7. (486 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
HOMER1Homer scaffold protein 1. (358 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
ENSPPAP00000018672EF-hand domain-containing protein. (78 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (260 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
ENSPPAP00000019421Uncharacterized protein. (75 aa)
EPHB2EPH receptor B2. (1039 aa)
ACTN2Actinin alpha 2. (872 aa)
CCL2C-C motif chemokine. (99 aa)
GNAS-2Uncharacterized protein. (245 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (899 aa)
LGALS3Galectin. (250 aa)
IAPPIslet amyloid polypeptide. (89 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
SPHK2Sphingosine kinase 2. (663 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
R3HDM2R3H domain containing 2. (1034 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
ENSPPAP00000022875Uncharacterized protein. (107 aa)
RGNRegucalcin. (299 aa)
RELNReelin. (3460 aa)
ENSPPAP00000023150Uncharacterized protein. (75 aa)
PPP3CCSerine/threonine-protein phosphatase. (504 aa)
FHL1Four and a half LIM domains 1. (339 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
CNTN1Contactin 1. (1018 aa)
SYT4Synaptotagmin 4. (425 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (555 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
EDN3Endothelin 3. (238 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (267 aa)
AKAP9A-kinase anchoring protein 9. (3880 aa)
ABCB1ATP binding cassette subfamily B member 1. (1220 aa)
CASRCalcium sensing receptor. (1078 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
ANO6Anoctamin. (906 aa)
ASPHAspartate beta-hydroxylase. (729 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
PLA2G1BPhospholipase A(2). (148 aa)
ADRB2Adrenoceptor beta 2. (429 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (873 aa)
GRM6Glutamate metabotropic receptor 6. (752 aa)
SSTR4Somatostatin receptor 4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
NPPANatriuretic peptide A. (153 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
ANK2Ankyrin 2. (3957 aa)
CXCL10C-X-C motif chemokine. (96 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
ENSPPAP00000030781Uncharacterized protein. (88 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
STIM1Stromal interaction molecule 1. (791 aa)
PLA2R1Phospholipase A2 receptor 1. (1466 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (242 aa)
LOC100970363Uncharacterized protein. (98 aa)
LOC100990946PA2c domain-containing protein. (147 aa)
CEMIPCell migration inducing hyaluronidase 1. (1361 aa)
ARRB2Arrestin beta 2. (447 aa)
ENSPPAP00000033087Uncharacterized protein. (751 aa)
ATF4Activating transcription factor 4. (340 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
CXCL9C-X-C motif chemokine. (125 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
AKAP7A-kinase anchoring protein 7. (348 aa)
BAXBCL2 associated X, apoptosis regulator. (218 aa)
STACSH3 and cysteine rich domain. (402 aa)
ANK3Ankyrin 3. (4364 aa)
LOC100995958Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (268 aa)
KCNC2Ion_trans domain-containing protein; Belongs to the potassium channel family. (240 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
KCNK3Potassium channel subfamily K member. (378 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
ACTN4Actinin alpha 4. (931 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
JAK3Tyrosine-protein kinase. (1090 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
WNK4WNK lysine deficient protein kinase 4. (1278 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (240 aa)
WNK2WNK lysine deficient protein kinase 2. (2240 aa)
LOC106634824Glutaredoxin domain-containing protein. (105 aa)
CHP2Calcineurin like EF-hand protein 2. (196 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
TOR2ATorsin. (321 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (506 aa)
GIMAP1Uncharacterized protein. (500 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (248 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
LRRC52Leucine rich repeat containing 52. (313 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (431 aa)
DMDDystrophin. (3517 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
TCAF1TRPM8 channel associated factor 1. (920 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (969 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (405 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSPPAP00000041551Uncharacterized protein. (69 aa)
LACRTLacritin. (137 aa)
TESCTescalcin. (214 aa)
GLRXGlutaredoxin domain-containing protein. (106 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (393 aa)
ENSPPAP00000042341Ig-like domain-containing protein. (484 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
NIPSNAP2Nipsnap homolog 2. (255 aa)
CCL5C-C motif chemokine. (91 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1403 aa)
RYR2Ryanodine receptor 2. (4948 aa)
MLLT6MLLT6, PHD finger containing. (1056 aa)
RAB3BRAB3B, member RAS oncogene family. (228 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (12%) [HD]