(23 nodes) Positive regulation of leukocyte degranulation network (Pan paniscus)

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Your Input:
	GATA2	GATA binding protein 2. (480 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
	PTAFR	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	F2RL1	F2R like trypsin receptor 1. (397 aa)
	STXBP1	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	LOC106634416	Uncharacterized protein. (144 aa)
	ITGB2	Integrin beta. (806 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	VAMP7	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (260 aa)
	CD160	Uncharacterized protein. (234 aa)
	IL4R	Interleukin 4 receptor. (873 aa)
	SYK	Tyrosine-protein kinase. (635 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
	LAMP1	Lysosomal associated membrane protein 1. (465 aa)
	GATA1	GATA binding protein 1. (413 aa)
	SPHK2	Sphingosine kinase 2. (663 aa)
	AP1G1	AP-1 complex subunit gamma. (844 aa)
	VAMP8	Vesicle associated membrane protein 8. (100 aa)
	PLA2G3	Phospholipase A2 group III. (509 aa)
	FGR	Tyrosine-protein kinase. (529 aa)
	SNX4	Sorting nexin 4. (450 aa)
	ADORA2B	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (357 aa)
	HLA-F	Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (441 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	VAMP7	ENSPPAP00000016567	ENSPPAP00000019219	AP-1 complex subunit gamma.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.648
AP1G1	VAMP8	ENSPPAP00000016567	ENSPPAP00000015935	AP-1 complex subunit gamma.	Vesicle associated membrane protein 8.	0.569
CD160	ITGAM	ENSPPAP00000018808	ENSPPAP00000028433	Uncharacterized protein.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.400
F2RL1	SPHK2	ENSPPAP00000005881	ENSPPAP00000022069	F2R like trypsin receptor 1.	Sphingosine kinase 2.	0.551
FGR	ITGAM	ENSPPAP00000012268	ENSPPAP00000028433	Tyrosine-protein kinase.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.428
FGR	ITGB2	ENSPPAP00000012268	ENSPPAP00000021180	Tyrosine-protein kinase.	Integrin beta.	0.509
FGR	SYK	ENSPPAP00000012268	ENSPPAP00000029310	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.674
GATA1	GATA2	ENSPPAP00000023388	ENSPPAP00000009054	GATA binding protein 1.	GATA binding protein 2.	0.834
GATA2	GATA1	ENSPPAP00000009054	ENSPPAP00000023388	GATA binding protein 2.	GATA binding protein 1.	0.834
IL4	IL4R	ENSPPAP00000008567	ENSPPAP00000037746	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Interleukin 4 receptor.	0.973
IL4	ITGAM	ENSPPAP00000008567	ENSPPAP00000028433	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.590
IL4	LOC106634416	ENSPPAP00000008567	ENSPPAP00000000718	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Uncharacterized protein.	0.418
IL4	SYK	ENSPPAP00000008567	ENSPPAP00000029310	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Tyrosine-protein kinase.	0.533
IL4R	IL4	ENSPPAP00000037746	ENSPPAP00000008567	Interleukin 4 receptor.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.973
ITGAM	CD160	ENSPPAP00000028433	ENSPPAP00000018808	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Uncharacterized protein.	0.400
ITGAM	FGR	ENSPPAP00000028433	ENSPPAP00000012268	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Tyrosine-protein kinase.	0.428
ITGAM	IL4	ENSPPAP00000028433	ENSPPAP00000008567	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.590
ITGAM	ITGB2	ENSPPAP00000028433	ENSPPAP00000021180	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Integrin beta.	0.999
ITGAM	LAMP1	ENSPPAP00000028433	ENSPPAP00000023617	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Lysosomal associated membrane protein 1.	0.539
ITGAM	PTAFR	ENSPPAP00000028433	ENSPPAP00000006186	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.433