(14 nodes) Spanning component of plasma membrane network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1359 aa)
	TRPM4	Transient receptor potential cation channel subfamily M member 4. (1138 aa)
	CDHR5	Cadherin related family member 5. (758 aa)
	ERBB3	Erb-b2 receptor tyrosine kinase 3. (1344 aa)
	TM2D3	TM2 domain containing 3. (246 aa)
	CDHR2	Cadherin related family member 2. (1310 aa)
	SLC15A2	Solute carrier family 15 member 2. (729 aa)
	AJAP1	Adherens junctions associated protein 1. (409 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1386 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	CD5	CD5 molecule. (495 aa)
	EGFR	Receptor protein-tyrosine kinase. (1201 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
	CD6	CD6 molecule. (644 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD5	CD6	ENSPPAP00000034621	ENSPPAP00000029521	CD5 molecule.	CD6 molecule.	0.749
CD6	CD5	ENSPPAP00000029521	ENSPPAP00000034621	CD6 molecule.	CD5 molecule.	0.749
CDHR2	CDHR5	ENSPPAP00000028265	ENSPPAP00000019334	Cadherin related family member 2.	Cadherin related family member 5.	0.955
CDHR5	CDHR2	ENSPPAP00000019334	ENSPPAP00000028265	Cadherin related family member 5.	Cadherin related family member 2.	0.955
EGFR	ERBB2	ENSPPAP00000043172	ENSPPAP00000037400	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	ERBB3	ENSPPAP00000043172	ENSPPAP00000024596	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.998
EGFR	ERBB4	ENSPPAP00000043172	ENSPPAP00000037551	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.949
EGFR	NPC1L1	ENSPPAP00000043172	ENSPPAP00000012162	Receptor protein-tyrosine kinase.	NPC1 like intracellular cholesterol transporter 1.	0.799
ERBB2	EGFR	ENSPPAP00000037400	ENSPPAP00000043172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
ERBB2	ERBB3	ENSPPAP00000037400	ENSPPAP00000024596	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.999
ERBB2	ERBB4	ENSPPAP00000037400	ENSPPAP00000037551	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.997
ERBB3	EGFR	ENSPPAP00000024596	ENSPPAP00000043172	Erb-b2 receptor tyrosine kinase 3.	Receptor protein-tyrosine kinase.	0.998
ERBB3	ERBB2	ENSPPAP00000024596	ENSPPAP00000037400	Erb-b2 receptor tyrosine kinase 3.	Receptor protein-tyrosine kinase.	0.999
ERBB3	ERBB4	ENSPPAP00000024596	ENSPPAP00000037551	Erb-b2 receptor tyrosine kinase 3.	Receptor protein-tyrosine kinase.	0.989
ERBB4	EGFR	ENSPPAP00000037551	ENSPPAP00000043172	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.949
ERBB4	ERBB2	ENSPPAP00000037551	ENSPPAP00000037400	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.997
ERBB4	ERBB3	ENSPPAP00000037551	ENSPPAP00000024596	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.989
NPC1L1	EGFR	ENSPPAP00000012162	ENSPPAP00000043172	NPC1 like intracellular cholesterol transporter 1.	Receptor protein-tyrosine kinase.	0.799