STRINGSTRING
PSORS1C2 PSORS1C2 HKDC1 HKDC1 PHKG2 PHKG2 GABARAPL1 GABARAPL1 PYGL PYGL SLC37A4 SLC37A4 BRAF BRAF ACADM ACADM POMK POMK AGL AGL PHKA2 PHKA2 ENSPPAP00000026998 ENSPPAP00000026998 GSK3A GSK3A GNE GNE ITPK1 ITPK1 ITPKA ITPKA HAS1 HAS1 HK3 HK3 PFKM PFKM PCK1 PCK1 INPP1 INPP1 GLB1 GLB1 NEU2 NEU2 STK40 STK40 NAGK NAGK PGD PGD INPP5J INPP5J GK GK IPPK IPPK HK2 HK2 LOC100987024 LOC100987024 COQ2 COQ2 B4GALT1 B4GALT1 UGP2 UGP2 ENSPPAP00000032115 ENSPPAP00000032115 ENSPPAP00000032308 ENSPPAP00000032308 GALK2 GALK2 MIOX MIOX IDH1 IDH1 NDST4 NDST4 B3GNT4 B3GNT4 GAL3ST3 GAL3ST3 B3GNT3 B3GNT3 GYS1 GYS1 LOC100995377 LOC100995377 HS2ST1 HS2ST1 KHK KHK PFKFB4 PFKFB4 INPP5E INPP5E HK1 HK1 RB1CC1 RB1CC1 AKT1 AKT1 GNPTG GNPTG CSGALNACT2 CSGALNACT2 EPM2A EPM2A GSK3B GSK3B PHKB PHKB SHPK SHPK LEPR LEPR ENSPPAP00000022871 ENSPPAP00000022871 RPE RPE PYGB PYGB FBP2 FBP2 MECP2 MECP2 ENSPPAP00000021656 ENSPPAP00000021656 PCK2 PCK2 ENSPPAP00000021452 ENSPPAP00000021452 NDST1 NDST1 GYG1 GYG1 PHKG1 PHKG1 STBD1 STBD1 LOC100985154 LOC100985154 RBKS RBKS LOC100971183 LOC100971183 ENSPPAP00000019387 ENSPPAP00000019387 PPP1R3B PPP1R3B IDH2 IDH2 IDUA IDUA ENSPPAP00000017065 ENSPPAP00000017065 IMPA1 IMPA1 NDST3 NDST3 FGGY FGGY G6PC G6PC HAS2 HAS2 ANGPTL3 ANGPTL3 BPNT1 BPNT1 PPP1R1A PPP1R1A LALBA LALBA B3GNT7 B3GNT7 GPD2 GPD2 GCK GCK PPP1CC PPP1CC PRKAG2 PRKAG2 PYGM PYGM B4GALT5 B4GALT5 PTEN PTEN PPP1CB PPP1CB SYNJ2 SYNJ2 PGP PGP NDST2 NDST2 AKT2 AKT2 PRKAG3 PRKAG3 ENOSF1 ENOSF1 SI SI PFKL PFKL FCSK FCSK TKFC TKFC PFKFB3 PFKFB3 ABHD10 ABHD10 PPP1R3E PPP1R3E PPIP5K2 PPIP5K2 IDNK IDNK SYNJ1 SYNJ1 MGAM MGAM ENSPPAP00000006992 ENSPPAP00000006992 GALK1 GALK1 ENSPPAP00000006512 ENSPPAP00000006512 B3GNT8 B3GNT8 B3GNT2 B3GNT2 XYLB XYLB GK2 GK2 PPP1CA PPP1CA GUSB GUSB GAA GAA OCRL OCRL EPM2AIP1 EPM2AIP1 EXT1 EXT1 IL6ST IL6ST CSGALNACT1 CSGALNACT1 SLC5A3 SLC5A3 IMPA2 IMPA2 DGAT2 DGAT2 AOAH AOAH PTGES3 PTGES3 MOGAT2 MOGAT2 NHLRC1 NHLRC1 ISYNA1 ISYNA1 PPP1R3G PPP1R3G ENSPPAP00000002153 ENSPPAP00000002153 MTMR7 MTMR7 INPP5B INPP5B LCT LCT B3GNT6 B3GNT6 PFKP PFKP GNPTAB GNPTAB LOC100992102 LOC100992102 ENSPPAP00000037171 ENSPPAP00000037171 EXT2 EXT2 PGM2 PGM2 TREH TREH PPP1R3A PPP1R3A PPP1R3C PPP1R3C PFKFB2 PFKFB2 GK5 GK5 GBE1 GBE1 INPP5A INPP5A GYS2 GYS2 PHKA1 PHKA1 MOGAT1 MOGAT1 INPP5K INPP5K MTMR2 MTMR2 GOT1 GOT1 IMPAD1 IMPAD1 GYG2 GYG2 INPP4B INPP4B FBP1 FBP1 NR1D1 NR1D1 PER2 PER2 PLA2G4A PLA2G4A PFKFB1 PFKFB1 PCDH12 PCDH12 MOGAT3 MOGAT3 GANC GANC PPP1R2 PPP1R2 HAS3 HAS3 TPI1 TPI1 B3GNT9 B3GNT9 ENSPPAP00000000351 ENSPPAP00000000351 FUT9 FUT9 GNMT GNMT COQ3 COQ3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSORS1C2Psoriasis susceptibility 1 candidate 2. (136 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
GABARAPL1Uncharacterized protein. (117 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (453 aa)
POMKProtein O-mannose kinase. (350 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa)
ENSPPAP00000026998Uncharacterized protein. (493 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (463 aa)
GNEGlucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (753 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (414 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (385 aa)
HAS1Hyaluronan synthase 1. (590 aa)
HK3Hexokinase 3. (923 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
INPP1Inositol polyphosphate-1-phosphatase. (399 aa)
GLB1Beta-galactosidase. (710 aa)
NEU2Neuraminidase 2. (380 aa)
STK40Serine/threonine kinase 40. (435 aa)
NAGKN-acetylglucosamine kinase. (392 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1007 aa)
GKGlycerol kinase; Belongs to the FGGY kinase family. (564 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (481 aa)
HK2Hexokinase 2. (917 aa)
LOC100987024Uncharacterized protein; Belongs to the FGGY kinase family. (521 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (421 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (496 aa)
ENSPPAP00000032115Uncharacterized protein. (883 aa)
ENSPPAP000000323086PGD domain-containing protein. (416 aa)
GALK2Galactokinase 2. (458 aa)
MIOXMyo-inositol oxygenase. (285 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
NDST4N-deacetylase and N-sulfotransferase 4. (872 aa)
B3GNT4Hexosyltransferase. (378 aa)
GAL3ST3Uncharacterized protein. (257 aa)
B3GNT3Hexosyltransferase. (372 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
LOC100995377Uncharacterized protein. (557 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1. (356 aa)
KHKKetohexokinase. (298 aa)
PFKFB46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4. (469 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (560 aa)
HK1Hexokinase 1. (921 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
GNPTGN-acetylglucosamine-1-phosphate transferase subunit gamma. (305 aa)
CSGALNACT2Hexosyltransferase. (542 aa)
EPM2AUncharacterized protein. (193 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1093 aa)
SHPKFGGY_N domain-containing protein. (479 aa)
LEPRLeptin receptor. (1165 aa)
ENSPPAP00000022871Uncharacterized protein. (373 aa)
RPEUncharacterized protein. (252 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (819 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (493 aa)
ENSPPAP00000021656Inositol-1-monophosphatase. (313 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
ENSPPAP00000021452Uncharacterized protein. (608 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
GYG1Glycogenin 1. (354 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (419 aa)
STBD1Starch binding domain 1. (358 aa)
LOC100985154Triosephosphate isomerase. (242 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (322 aa)
LOC100971183Uncharacterized protein. (152 aa)
ENSPPAP00000019387Uncharacterized protein. (207 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (428 aa)
IDUAIduronidase alpha-L-. (637 aa)
ENSPPAP00000017065SER_THR_PHOSPHATASE domain-containing protein. (297 aa)
IMPA1Inositol-1-monophosphatase. (336 aa)
NDST3N-deacetylase and N-sulfotransferase 3. (887 aa)
FGGYFGGY carbohydrate kinase domain containing. (551 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
HAS2Hyaluronan synthase 2. (552 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (349 aa)
PPP1R1AProtein phosphatase 1 regulatory inhibitor subunit 1A. (177 aa)
LALBALactalbumin alpha; Belongs to the glycosyl hydrolase 22 family. (142 aa)
B3GNT7Hexosyltransferase. (402 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (753 aa)
GCKPhosphotransferase. (463 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (371 aa)
PTENUncharacterized protein. (542 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
SYNJ2Synaptojanin 2. (1498 aa)
PGPUncharacterized protein. (122 aa)
NDST2Uncharacterized protein. (872 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ENOSF1Enolase superfamily member 1. (443 aa)
SISucrase-isomaltase. (1826 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (771 aa)
FCSKFucose kinase. (1084 aa)
TKFCTriokinase and FMN cyclase. (576 aa)
PFKFB36PF2K domain-containing protein. (633 aa)
ABHD10Abhydrolase domain containing 10. (306 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (280 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1278 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (187 aa)
SYNJ1Synaptojanin 1. (1614 aa)
MGAMUncharacterized protein. (2753 aa)
ENSPPAP00000006992Uncharacterized protein. (169 aa)
GALK1Galactokinase 1. (422 aa)
ENSPPAP00000006512Uncharacterized protein. (80 aa)
B3GNT8Hexosyltransferase. (397 aa)
B3GNT2Hexosyltransferase. (397 aa)
XYLBXylulokinase. (536 aa)
GK2Glycerol kinase 2; Belongs to the FGGY kinase family. (553 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (592 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (887 aa)
EPM2AIP1EPM2A interacting protein 1. (607 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
CSGALNACT1Hexosyltransferase. (532 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
AOAHAcyloxyacyl hydrolase. (688 aa)
PTGES3Prostaglandin E synthase 3. (164 aa)
MOGAT2Monoacylglycerol O-acyltransferase 2. (334 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
ISYNA1Inositol-3-phosphate synthase 1. (558 aa)
PPP1R3GProtein phosphatase 1 regulatory subunit 3G. (358 aa)
ENSPPAP00000002153Triosephosphate isomerase. (137 aa)
MTMR7Myotubularin related protein 7. (660 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (997 aa)
LCTLactase. (1927 aa)
B3GNT6Hexosyltransferase. (384 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1256 aa)
LOC100992102CS domain-containing protein. (137 aa)
ENSPPAP00000037171Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (891 aa)
PGM2Phosphoglucomutase 2. (612 aa)
TREHTrehalase. (583 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1140 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (522 aa)
GK5Glycerol kinase 5; Belongs to the FGGY kinase family. (529 aa)
GBE11,4-alpha-glucan branching enzyme 1. (702 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (396 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1240 aa)
MOGAT1Monoacylglycerol O-acyltransferase 1. (334 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
MTMR2Myotubularin related protein 2. (643 aa)
GOT1Aspartate aminotransferase. (413 aa)
IMPAD1Inositol monophosphatase domain containing 1. (357 aa)
GYG2Glycogenin 2. (501 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
PER2Period circadian regulator 2. (1255 aa)
PLA2G4APhospholipase A2. (749 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
PCDH12Protocadherin 12. (1184 aa)
MOGAT3Monoacylglycerol O-acyltransferase 3. (344 aa)
GANCGal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (891 aa)
PPP1R2Protein phosphatase 1 regulatory inhibitor subunit 2. (205 aa)
HAS3Hyaluronan synthase 3. (553 aa)
TPI1Triosephosphate isomerase. (237 aa)
B3GNT9Hexosyltransferase. (402 aa)
ENSPPAP00000000351Uncharacterized protein. (306 aa)
FUT9Fucosyltransferase 9. (359 aa)
GNMTGlycine N-methyltransferase. (295 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (369 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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