STRINGSTRING
GDF3 GDF3 LOC103783761 LOC103783761 GRHL2 GRHL2 NOTCH1 NOTCH1 TP63 TP63 DLL1 DLL1 HOXA7 HOXA7 SRSF6 SRSF6 OVOL2 OVOL2 EZH2 EZH2 REG3G REG3G REG3A REG3A HES1 HES1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GDF3Growth differentiation factor 3. (364 aa)
LOC103783761RRM domain-containing protein. (291 aa)
GRHL2Grainyhead like transcription factor 2. (618 aa)
NOTCH1Notch receptor 1. (2573 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
HOXA7Homeobox protein Hox-A7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (230 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
OVOL2Ovo like zinc finger 2. (225 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
REG3GRegenerating family member 3 gamma. (175 aa)
REG3ARegenerating family member 3 alpha. (175 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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