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| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | FOXN1 | Forkhead box N1. (648 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (816 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (253 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | ARID2 | AT-rich interaction domain 2. (1835 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa) |
| | PHF10 | PHD finger protein 10. (469 aa) |
| | TNFSF18 | TNF superfamily member 18. (199 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | ENSPPAP00000001242 | BHLH domain-containing protein. (117 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | IL10 | Interleukin 10. (178 aa) |
| | IL7 | Interleukin 7. (179 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1036 aa) |
| | ENSPPAP00000004517 | Uncharacterized protein. (654 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | LOXL3 | Lysyl oxidase like 3. (753 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | IFNL1 | Interferon lambda 1. (200 aa) |
| | PBRM1 | Polybromo 1. (1690 aa) |
| | NFAM1 | NFAT activating protein with ITAM motif 1. (270 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | MDK | Midkine. (143 aa) |
| | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) |
| | ADA | Adenosine deaminase. (412 aa) |
| | PRDM1 | PR/SET domain 1. (825 aa) |
| | LOC100973702 | Uncharacterized protein. (201 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (200 aa) |
| | LAG3 | Lymphocyte activating 3. (527 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | FANCD2 | FA complementation group D2. (1259 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa) |
| | ENSPPAP00000009290 | Uncharacterized protein. (354 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (291 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | FOXP3 | Forkhead box P3. (441 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | ENSPPAP00000010058 | Uncharacterized protein. (165 aa) |
| | LOC100985819 | Uncharacterized protein. (377 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa) |
| | FCRL3 | Fc receptor like 3. (742 aa) |
| | BMP4 | TGF_BETA_2 domain-containing protein. (402 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ENSPPAP00000011953 | Ku domain-containing protein. (586 aa) |
| | ARID1B | ARID domain-containing protein. (1539 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | SOX13 | SRY-box transcription factor 13. (622 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | ENSPPAP00000013500 | PRELI/MSF1 domain-containing protein. (139 aa) |
| | BTN2A2 | Butyrophilin subfamily 2 member A2. (523 aa) |
| | LOC106634832 | Uncharacterized protein. (178 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa) |
| | IL15RA | Sushi domain-containing protein. (278 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (478 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (662 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) |
| | TMEM131L | Transmembrane 131 like. (1617 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (766 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (464 aa) |
| | IRF1 | Interferon regulatory factor. (325 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | FOXJ1 | Forkhead box J1. (405 aa) |
| | ENSPPAP00000026998 | Uncharacterized protein. (493 aa) |
| | CD27 | CD27 molecule. (260 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | GLI2 | GLI family zinc finger 2. (1587 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1207 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (547 aa) |
| | MMP14 | Matrix metallopeptidase 14. (582 aa) |
| | MALT1 | MALT1 paracaspase. (786 aa) |
| | ENSPPAP00000028807 | Thioredoxin domain-containing protein. (166 aa) |
| | CD74 | CD74 molecule. (296 aa) |
| | DROSHA | Drosha ribonuclease III. (1369 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | AXL | AXL receptor tyrosine kinase. (894 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1035 aa) |
| | HMGB3 | Uncharacterized protein. (207 aa) |
| | TESPA1 | Thymocyte expressed, positive selection associated 1. (473 aa) |
| | CLPTM1 | CLPTM1 regulator of GABA type A receptor forward trafficking. (667 aa) |
| | NKAP | NFKB activating protein. (415 aa) |
| | GAS6 | Growth arrest specific 6. (679 aa) |
| | CD2 | CD2 molecule. (351 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1189 aa) |
| | FBXO7 | F-box protein 7. (509 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1087 aa) |
| | HLA-G | Major histocompatibility complex, class I, G; Belongs to the MHC class I family. (355 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (595 aa) |
| | SMAD7 | MH2 domain-containing protein. (211 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ZFP36L2 | Uncharacterized protein. (413 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (430 aa) |
| | HLX | H2.0 like homeobox. (493 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (768 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
| | ENSPPAP00000019394 | HMG box domain-containing protein. (174 aa) |
| | IL27 | Uncharacterized protein. (154 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | ENSPPAP00000020189 | Uncharacterized protein. (192 aa) |
| | FANCA | FA complementation group A. (1420 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | FGL2 | Fibrinogen like 2. (439 aa) |
| | SHB | SH2 domain-containing protein. (285 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | ENSPPAP00000021246 | SOCS box domain-containing protein. (478 aa) |
| | TBX21 | T-box transcription factor 21. (494 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (402 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (888 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa) |
| | PRDX2 | Peroxiredoxin 2. (198 aa) |
| | VNN1 | Vanin 1. (513 aa) |
| | PGLYRP2 | Peptidoglycan recognition protein 2. (633 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | TCF7 | HMG box domain-containing protein. (391 aa) |
| | SFRP1 | NTR domain-containing protein. (178 aa) |
| | ID2 | Inhibitor of DNA binding 2. (134 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1261 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | ENSPPAP00000022942 | Ku domain-containing protein. (338 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (706 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (426 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | ENSPPAP00000023714 | Uncharacterized protein. (82 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | ENSPPAP00000023917 | Uncharacterized protein. (311 aa) |
| | ENSPPAP00000023985 | Uncharacterized protein. (183 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (661 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2150 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (466 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (272 aa) |
| | PGLYRP3 | Peptidoglycan recognition protein 3. (341 aa) |
| | RARA | Uncharacterized protein. (609 aa) |
| | ENSPPAP00000042766 | SAP domain-containing protein. (225 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | JAK3 | Tyrosine-protein kinase. (1090 aa) |
| | IRF4 | Interferon regulatory factor 4. (392 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1094 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | PRELID1 | PRELI domain containing 1. (219 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | ENSPPAP00000031093 | PRELI/MSF1 domain-containing protein. (213 aa) |
| | CDKN2A | Uncharacterized protein. (173 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | ZNF683 | Zinc finger protein 683. (524 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1127 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (424 aa) |
| | BRD7 | Bromodomain containing 7. (644 aa) |
| | NFKBID | ANK_REP_REGION domain-containing protein. (465 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | PGLYRP1 | Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1566 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (430 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1134 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (843 aa) |
| | CD80 | CD80 molecule. (288 aa) |
| | VNN3 | CN hydrolase domain-containing protein. (501 aa) |
| | PCID2 | PCI domain containing 2. (397 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | STAT5B | Signal transducer and activator of transcription. (789 aa) |
| | IL4I1 | Amine oxidase. (589 aa) |
| | SLC46A2 | Solute carrier family 46 member 2. (475 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | ENSPPAP00000034946 | Uncharacterized protein. (276 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | LILRB4 | Leukocyte immunoglobulin like receptor B4. (408 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa) |
| | CAMK4 | Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa) |
| | SOX4 | HMG box domain-containing protein. (251 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | IL4R | Interleukin 4 receptor. (873 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte associated protein 4. (223 aa) |
| | CD83 | CD83 molecule. (205 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | GIMAP1 | Uncharacterized protein. (500 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
