STRINGSTRING
ENSPPAP00000031824 ENSPPAP00000031824 ARNT ARNT MED1 MED1 STAT5B STAT5B STAT1 STAT1 KAT7 KAT7 ABCB10 ABCB10 MAPK14 MAPK14 ENSPPAP00000039636 ENSPPAP00000039636 ENSPPAP00000042728 ENSPPAP00000042728 ACVR2A ACVR2A STAT3 STAT3 INHBA INHBA SMAP1 SMAP1 PRMT1 PRMT1 GATA1 GATA1 TAL1 TAL1 ANKRD54 ANKRD54 ACVR1B ACVR1B INPP5D INPP5D FAM210B FAM210B ISG15 ISG15 PRKDC PRKDC HIF1A HIF1A BRD1 BRD1 GATA2 GATA2 ZNF16 ZNF16 ETS1 ETS1 RHEX RHEX NCKAP1L NCKAP1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPAP00000031824Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
ABCB10ATP binding cassette subfamily B member 10. (609 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSPPAP00000039636DUF1279 domain-containing protein. (209 aa)
ENSPPAP00000042728Uncharacterized protein. (325 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
INHBAInhibin subunit beta A. (426 aa)
SMAP1Small ArfGAP 1. (496 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
GATA1GATA binding protein 1. (413 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (291 aa)
ANKRD54ANK_REP_REGION domain-containing protein. (180 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1189 aa)
FAM210BDUF1279 domain-containing protein. (178 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
BRD1Bromodomain containing 1. (1189 aa)
GATA2GATA binding protein 2. (480 aa)
ZNF16Zinc finger protein 16; Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis (By similarity). (673 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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