STRINGSTRING
SPDYC SPDYC AKT1 AKT1 SRC SRC CKS2 CKS2 SPDYE4 SPDYE4 CCNB1 CCNB1 EGFR EGFR CDK5R1 CDK5R1 CKS1B CKS1B PSMD10 PSMD10 PROX1 PROX1 MAPRE3 MAPRE3 ENSPPAP00000026571 ENSPPAP00000026571 CCND2 CCND2 SPDYA SPDYA CCNT2 CCNT2 ENSPPAP00000028050 ENSPPAP00000028050 ADAM17 ADAM17 CDC6 CDC6 ENSPPAP00000032343 ENSPPAP00000032343 ENSPPAP00000031945 ENSPPAP00000031945 CCNY CCNY CCND3 CCND3 LOC100996179 LOC100996179 PIM1 PIM1 ENSPPAP00000011994 ENSPPAP00000011994 CDKN1B CDKN1B ENSPPAP00000021459 ENSPPAP00000021459 PDGFB PDGFB PSRC1 PSRC1 CCNYL1 CCNYL1 RGCC RGCC ENSPPAP00000023415 ENSPPAP00000023415 MNAT1 MNAT1 CCNK CCNK LOC100974443 LOC100974443 CCNT1 CCNT1 ENSPPAP00000017784 ENSPPAP00000017784 PKD2 PKD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPDYCSpeedy/RINGO cell cycle regulator family member C. (317 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
SRCTyrosine-protein kinase. (458 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
SPDYE4Speedy/RINGO cell cycle regulator family member E4. (237 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (351 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PROX1Prospero homeobox 1. (737 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
ENSPPAP00000026571Uncharacterized protein. (67 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (313 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
ENSPPAP00000028050Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (93 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
ENSPPAP00000032343Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (88 aa)
ENSPPAP00000031945ANK_REP_REGION domain-containing protein. (152 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
LOC100996179CYCLIN domain-containing protein. (360 aa)
PIM1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (406 aa)
ENSPPAP00000011994ANK_REP_REGION domain-containing protein. (190 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ENSPPAP00000021459Cyclin N-terminal domain-containing protein. (350 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PSRC1Proline and serine rich coiled-coil 1. (363 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
RGCCRegulator of cell cycle. (137 aa)
ENSPPAP00000023415Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNKCyclin K; Belongs to the cyclin family. (576 aa)
LOC100974443Uncharacterized protein. (296 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (707 aa)
ENSPPAP00000017784Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (97 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (788 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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