(32 nodes) Positive regulation of epidermal growth factor receptor signaling pathway network (Pan paniscus)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	BTC	Betacellulin. (178 aa)
	CNOT9	CCR4-NOT transcription complex subunit 9. (331 aa)
	AGR2	Anterior gradient 2, protein disulphide isomerase family member. (189 aa)
	PDE6H	Phosphodiesterase 6H. (83 aa)
	ADAM17	ADAM metallopeptidase domain 17. (824 aa)
	CBL	Cbl proto-oncogene. (906 aa)
	MMP9	Matrix metallopeptidase 9. (707 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1056 aa)
	CCDC88A	Coiled-coil domain containing 88A. (1824 aa)
	HBEGF	Heparin binding EGF like growth factor. (208 aa)
	NEU3	Neuraminidase 3. (461 aa)
	AREG	EGF-like domain-containing protein. (274 aa)
	EREG	Epiregulin. (169 aa)
	TGFA	Transforming growth factor alpha. (181 aa)
	EPGN	Uncharacterized protein. (85 aa)
	SHKBP1	SH3KBP1 binding protein 1. (707 aa)
	PLAUR	Plasminogen activator, urokinase receptor. (335 aa)
	DGKD	Diacylglycerol kinase. (1254 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
	NUP62	Nsp1_C domain-containing protein. (419 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (485 aa)
	HIP1	Uncharacterized protein. (151 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
	HAP1	Huntingtin associated protein 1. (669 aa)
	PTK6	Tyrosine-protein kinase. (451 aa)
	FASLG	Fas ligand; Belongs to the tumor necrosis factor family. (280 aa)
	FBXW9	F-box and WD repeat domain containing 9. (478 aa)
	PDE6G	Uncharacterized protein. (137 aa)
	BCAR3	BCAR3 adaptor protein, NSP family member. (826 aa)
	AFAP1L2	Actin filament associated protein 1 like 2. (818 aa)
	NCF1	Neutrophil cytosolic factor 1. (390 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	AGT	ENSPPAP00000030429	ENSPPAP00000007994	ADAM metallopeptidase domain 17.	Angiotensinogen; Belongs to the serpin family.	0.539
ADAM17	AREG	ENSPPAP00000030429	ENSPPAP00000039357	ADAM metallopeptidase domain 17.	EGF-like domain-containing protein.	0.540
ADAM17	BTC	ENSPPAP00000030429	ENSPPAP00000019590	ADAM metallopeptidase domain 17.	Betacellulin.	0.525
ADAM17	EGF	ENSPPAP00000030429	ENSPPAP00000000469	ADAM metallopeptidase domain 17.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.542
ADAM17	EREG	ENSPPAP00000030429	ENSPPAP00000039948	ADAM metallopeptidase domain 17.	Epiregulin.	0.525
ADAM17	HBEGF	ENSPPAP00000030429	ENSPPAP00000033567	ADAM metallopeptidase domain 17.	Heparin binding EGF like growth factor.	0.578
ADAM17	MMP9	ENSPPAP00000030429	ENSPPAP00000031206	ADAM metallopeptidase domain 17.	Matrix metallopeptidase 9.	0.459
ADAM17	TGFA	ENSPPAP00000030429	ENSPPAP00000040828	ADAM metallopeptidase domain 17.	Transforming growth factor alpha.	0.783
AGT	ADAM17	ENSPPAP00000007994	ENSPPAP00000030429	Angiotensinogen; Belongs to the serpin family.	ADAM metallopeptidase domain 17.	0.539
AGT	EGF	ENSPPAP00000007994	ENSPPAP00000000469	Angiotensinogen; Belongs to the serpin family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.454
AGT	MMP9	ENSPPAP00000007994	ENSPPAP00000031206	Angiotensinogen; Belongs to the serpin family.	Matrix metallopeptidase 9.	0.595
AGT	NCF1	ENSPPAP00000007994	ENSPPAP00000017382	Angiotensinogen; Belongs to the serpin family.	Neutrophil cytosolic factor 1.	0.584
AREG	ADAM17	ENSPPAP00000039357	ENSPPAP00000030429	EGF-like domain-containing protein.	ADAM metallopeptidase domain 17.	0.540
AREG	BTC	ENSPPAP00000039357	ENSPPAP00000019590	EGF-like domain-containing protein.	Betacellulin.	0.876
AREG	CBL	ENSPPAP00000039357	ENSPPAP00000031194	EGF-like domain-containing protein.	Cbl proto-oncogene.	0.503
AREG	EGF	ENSPPAP00000039357	ENSPPAP00000000469	EGF-like domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.938
AREG	EPGN	ENSPPAP00000039357	ENSPPAP00000042220	EGF-like domain-containing protein.	Uncharacterized protein.	0.782
AREG	EREG	ENSPPAP00000039357	ENSPPAP00000039948	EGF-like domain-containing protein.	Epiregulin.	0.934
AREG	HBEGF	ENSPPAP00000039357	ENSPPAP00000033567	EGF-like domain-containing protein.	Heparin binding EGF like growth factor.	0.699
AREG	SOS1	ENSPPAP00000039357	ENSPPAP00000008514	EGF-like domain-containing protein.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.408