STRINGSTRING
IGF2R IGF2R PLCB1 PLCB1 IGFBP5 IGFBP5 IGF1R IGF1R GIGYF1 GIGYF1 GHSR GHSR TSC2 TSC2 GHR GHR CRIM1 CRIM1 AR AR GIGYF2 GIGYF2 EIF2AK3 EIF2AK3 AKT1 AKT1 PIK3R1 PIK3R1 IRS1 IRS1 GRB10 GRB10 IGF1 IGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF2RInsulin like growth factor 2 receptor. (2464 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
IGF1RTyrosine-protein kinase receptor. (1389 aa)
GIGYF1GRB10 interacting GYF protein 1. (1046 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TSC2TSC complex subunit 2. (1807 aa)
GHRGrowth hormone receptor. (641 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1029 aa)
ARAndrogen receptor. (882 aa)
GIGYF2GRB10 interacting GYF protein 2. (1325 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
GRB10Growth factor receptor bound protein 10. (594 aa)
IGF1IlGF domain-containing protein. (196 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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