STRINGSTRING
CPEB3 CPEB3 MAP1B MAP1B STAU1 STAU1 ADORA2A ADORA2A SCGN SCGN MEF2C MEF2C ATF4 ATF4 CRHR2 CRHR2 NR2E1 NR2E1 LGMN LGMN PSEN1 PSEN1 SLC4A10 SLC4A10 ERC2 ERC2 ENSPPAP00000031473 ENSPPAP00000031473 GIPC2 GIPC2 LZTS1 LZTS1 KRAS KRAS ENSPPAP00000030581 ENSPPAP00000030581 SCT SCT PTK2B PTK2B CPLX2 CPLX2 DLG4 DLG4 NTRK2 NTRK2 P2RX3 P2RX3 ADCY8 ADCY8 ITPKA ITPKA GRIK2 GRIK2 CBLN1 CBLN1 SYNPR SYNPR DBN1 DBN1 ENSPPAP00000026998 ENSPPAP00000026998 SORCS2 SORCS2 CX3CL1 CX3CL1 SYNGAP1 SYNGAP1 CD38 CD38 TSHZ3 TSHZ3 ABL1 ABL1 LOC100970522 LOC100970522 EGR2 EGR2 CYP46A1 CYP46A1 BRAF BRAF ZDHHC2 ZDHHC2 YWHAH YWHAH LOC100989438 LOC100989438 SYT4 SYT4 CDK5 CDK5 NPAS4 NPAS4 RELN RELN TNR TNR GRIN2D GRIN2D STAU2 STAU2 LOC100982269 LOC100982269 ERC1 ERC1 GRIN2A GRIN2A SQSTM1 SQSTM1 MPP2 MPP2 MECP2 MECP2 PRRT1 PRRT1 STX4 STX4 CX3CR1 CX3CR1 CHRDL1 CHRDL1 DGKI DGKI SYP SYP PTN PTN CAMK2B CAMK2B ADGRB1 ADGRB1 EPHB2 EPHB2 KIT KIT RGS14 RGS14 NCSTN NCSTN EPHA4 EPHA4 MCTP1 MCTP1 RARA RARA SYNGR1 SYNGR1 RASGRF2 RASGRF2 PENK PENK ANAPC2 ANAPC2 PTGS2 PTGS2 SHISA9 SHISA9 SLC24A1 SLC24A1 PRKCZ PRKCZ NSMF NSMF CALB1 CALB1 GFAP GFAP CAMK2A CAMK2A SYAP1 SYAP1 FMR1 FMR1 ENSPPAP00000038758 ENSPPAP00000038758 PRRT2 PRRT2 SYT7 SYT7 GIPC1 GIPC1 RAB5A RAB5A ENSPPAP00000037955 ENSPPAP00000037955 CALB2 CALB2 LOC100982004 LOC100982004 KAT2A KAT2A ENSPPAP00000037516 ENSPPAP00000037516 SERPINE2 SERPINE2 JPH3 JPH3 GSK3B GSK3B NPTN NPTN RIMS1 RIMS1 RAB8A RAB8A ITPR3 ITPR3 RIMS2 RIMS2 NCDN NCDN MAP1A MAP1A SORCS3 SORCS3 PLK2 PLK2 RIMS3 RIMS3 SHANK2 SHANK2 BRSK1 BRSK1 ENSPPAP00000033875 ENSPPAP00000033875 PAIP2 PAIP2 PRKAR1B PRKAR1B ABHD6 ABHD6 JPH4 JPH4 LOC100995377 LOC100995377 ADCY1 ADCY1 ARC ARC SIPA1L1 SIPA1L1 ZZEF1 ZZEF1 LRRTM1 LRRTM1 CRTC1 CRTC1 SHISA6 SHISA6 GRID2IP GRID2IP GIPC3 GIPC3 PPP3CB PPP3CB NOG NOG STX3 STX3 ACP4 ACP4 APP APP LOC100988977 LOC100988977 SCTR SCTR ENSPPAP00000002562 ENSPPAP00000002562 STXBP1 STXBP1 SLC24A2 SLC24A2 PLAT PLAT DRD1 DRD1 SLC8A3 SLC8A3 LOC100980724 LOC100980724 MME MME EIF4EBP2 EIF4EBP2 YTHDF1 YTHDF1 HRH1 HRH1 DRD5 DRD5 MAPK1 MAPK1 SNCA SNCA AKAP5 AKAP5 NFATC4 NFATC4 RASGRF1 RASGRF1 NETO1 NETO1 PPFIA3 PPFIA3 CHRNA7 CHRNA7 IGSF11 IGSF11 GRIN2B GRIN2B BAIAP2 BAIAP2 SLC1A1 SLC1A1 CNTN2 CNTN2 SNAP25 SNAP25 ACE ACE AGER AGER GRIA1 GRIA1 SRF SRF HRAS HRAS GRM5 GRM5 UNC13C UNC13C RAB3GAP1 RAB3GAP1 RAB3A RAB3A GRID2 GRID2 PTEN PTEN PICK1 PICK1 NSG1 NSG1 ARF1 ARF1 GIP GIP SYT12 SYT12 LOC100983911 LOC100983911 PRKCG PRKCG DRD2 DRD2 KCNB1 KCNB1 SNAP47 SNAP47 SLC8A2 SLC8A2 RAPGEF2 RAPGEF2 CDC20 CDC20 CNTN4 CNTN4 NF1 NF1 S100B S100B GRIN1 GRIN1 VGF VGF EIF2AK4 EIF2AK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPEB3Cytoplasmic polyadenylation element binding protein 3. (597 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
STAU1Staufen double-stranded RNA binding protein 1. (585 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
ATF4Activating transcription factor 4. (340 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (438 aa)
NR2E1Uncharacterized protein. (385 aa)
LGMNLegumain. (433 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
SLC4A10Anion exchange protein. (1138 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
ENSPPAP00000031473Uncharacterized protein. (117 aa)
GIPC2GIPC PDZ domain containing family member 2. (319 aa)
LZTS1Leucine zipper tumor suppressor 1. (596 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSPPAP00000030581Uncharacterized protein. (186 aa)
SCTUncharacterized protein. (172 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CPLX2Complexin 2. (134 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (385 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (869 aa)
CBLN1Cerebellin 1 precursor. (168 aa)
SYNPRSynaptoporin. (285 aa)
DBN1Drebrin 1. (677 aa)
ENSPPAP00000026998Uncharacterized protein. (493 aa)
SORCS2Sortilin related VPS10 domain containing receptor 2. (1027 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1346 aa)
CD38CD38 molecule. (300 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1081 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
LOC100970522G_PROTEIN_RECEP_F1_2 domain-containing protein. (432 aa)
EGR2Early growth response 2. (476 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (323 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (243 aa)
LOC100989438Uncharacterized protein. (873 aa)
SYT4Synaptotagmin 4. (425 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
RELNReelin. (3460 aa)
TNRTenascin R. (1360 aa)
GRIN2DUncharacterized protein. (806 aa)
STAU2Staufen double-stranded RNA binding protein 2. (608 aa)
LOC100982269Uncharacterized protein. (390 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SQSTM1Sequestosome 1. (440 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (597 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (493 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
CHRDL1Chordin like 1. (458 aa)
DGKIDiacylglycerol kinase. (905 aa)
SYPSynaptophysin. (313 aa)
PTNPleiotrophin. (172 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (644 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1568 aa)
EPHB2EPH receptor B2. (1039 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
RGS14Regulator of G protein signaling 14. (567 aa)
NCSTNNicastrin. (709 aa)
EPHA4EPH receptor A4. (986 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (953 aa)
RARAUncharacterized protein. (609 aa)
SYNGR1Synaptogyrin. (233 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
PENKProenkephalin. (267 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
SHISA9Shisa family member 9. (398 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1094 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (528 aa)
CALB1Calbindin 1. (261 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
SYAP1Synapse associated protein 1. (352 aa)
FMR1Fragile X mental retardation 1. (615 aa)
ENSPPAP00000038758MARVEL domain-containing protein. (202 aa)
PRRT2Proline rich transmembrane protein 2. (393 aa)
SYT7Uncharacterized protein. (686 aa)
GIPC1GIPC PDZ domain containing family member 1. (332 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
ENSPPAP00000037955BHLH domain-containing protein. (341 aa)
CALB2Calbindin 2. (271 aa)
LOC100982004Uncharacterized protein. (107 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
ENSPPAP00000037516Uncharacterized protein. (321 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
NPTNNeuroplastin. (390 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
RIMS2Uncharacterized protein. (1356 aa)
NCDNNeurochondrin. (729 aa)
MAP1AMicrotubule associated protein 1A. (3041 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1122 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SHANK2Uncharacterized protein. (1849 aa)
BRSK1BR serine/threonine kinase 1. (666 aa)
ENSPPAP00000033875Uncharacterized protein. (84 aa)
PAIP2Poly(A) binding protein interacting protein 2. (124 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
JPH4Junctophilin 4. (564 aa)
LOC100995377Uncharacterized protein. (557 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1804 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2963 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
CRTC1CREB regulated transcription coactivator 1. (622 aa)
SHISA6Shisa family member 6. (461 aa)
GRID2IPGrid2 interacting protein. (1055 aa)
GIPC3GIPC PDZ domain containing family member 3. (264 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
ACP4Acid phosphatase 4; Belongs to the histidine acid phosphatase family. (426 aa)
APPAmyloid beta precursor protein. (770 aa)
LOC100988977MARVEL domain-containing protein. (170 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (661 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
SLC8A3Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (210 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
MMEMembrane metalloendopeptidase. (750 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (119 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (584 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (477 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
NFATC4Nuclear factor of activated T cells 4. (963 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1270 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
PPFIA3PTPRF interacting protein alpha 3. (1226 aa)
CHRNA7Uncharacterized protein. (511 aa)
IGSF11Immunoglobulin superfamily member 11. (403 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
BAIAP2BAI1 associated protein 2. (549 aa)
SLC1A1Amino acid transporter. (524 aa)
CNTN2Contactin 2. (1040 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
ACEAngiotensin-converting enzyme. (1223 aa)
AGERAdvanced glycosylation end-product specific receptor. (420 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
SRFSerum response factor. (414 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GRM5Glutamate metabotropic receptor 5. (1195 aa)
UNC13CC2 domain-containing protein. (135 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (988 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
PTENUncharacterized protein. (542 aa)
PICK1Protein interacting with PRKCA 1. (415 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
GIPUncharacterized protein. (94 aa)
SYT12Synaptotagmin 12. (420 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (908 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1611 aa)
CDC20Cell division cycle 20. (499 aa)
CNTN4Contactin 4. (1027 aa)
NF1Neurofibromin 1. (2839 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
VGFUncharacterized protein. (513 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1734 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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