STRINGSTRING
LOC100992554 LOC100992554 CSNK1D CSNK1D GRIN3A GRIN3A ESR1 ESR1 LOC100986655 LOC100986655 RBM4B RBM4B MMP19 MMP19 ZNF830 ZNF830 ENSPPAP00000004673 ENSPPAP00000004673 ADAMTS1 ADAMTS1 CRTC1 CRTC1 SETX SETX PLEKHA1 PLEKHA1 ENSPPAP00000001242 ENSPPAP00000001242 MAPK8 MAPK8 NRIP1 NRIP1 NKX2-1 NKX2-1 PSPC1 PSPC1 ENSPPAP00000002562 ENSPPAP00000002562 ID3 ID3 CRY1 CRY1 ARNTL ARNTL ENSPPAP00000003540 ENSPPAP00000003540 OGT OGT ENSPPAP00000013852 ENSPPAP00000013852 GPR149 GPR149 SIN3A SIN3A CCDC90B CCDC90B NCOA2 NCOA2 EZH2 EZH2 ATF5 ATF5 ENSPPAP00000017065 ENSPPAP00000017065 SP1 SP1 TGFB3 TGFB3 SERPINF1 SERPINF1 LHCGR LHCGR PRMT5 PRMT5 FSHR FSHR HOMER1 HOMER1 NPAS2 NPAS2 HDAC1 HDAC1 ENSPPAP00000018727 ENSPPAP00000018727 DYRK1A DYRK1A NONO NONO ENSPPAP00000019077 ENSPPAP00000019077 EP300 EP300 NOS2 NOS2 BHLHE40 BHLHE40 HDAC2 HDAC2 PTN PTN ENSPPAP00000020094 ENSPPAP00000020094 PAX4 PAX4 PCNA PCNA PIWIL2 PIWIL2 SLIT3 SLIT3 HES7 HES7 NR1D2 NR1D2 KLF10 KLF10 PROKR2 PROKR2 SFPQ SFPQ NLGN1 NLGN1 LOC100980724 LOC100980724 ENSPPAP00000004842 ENSPPAP00000004842 ENSPPAP00000004862 ENSPPAP00000004862 NHLH2 NHLH2 TNFRSF11A TNFRSF11A MDK MDK BMPR1B BMPR1B PPP1CA PPP1CA SREBF1 SREBF1 CRY2 CRY2 NR5A1 NR5A1 MYBBP1A MYBBP1A ZFHX3 ZFHX3 GPR157 GPR157 DHX9 DHX9 AHR AHR DTL DTL TGFB2 TGFB2 TPH2 TPH2 CUL4A CUL4A SIRT6 SIRT6 KCNH7 KCNH7 ID2 ID2 BTRC BTRC NTRK1 NTRK1 LOC100975570 LOC100975570 KCND2 KCND2 PPARGC1A PPARGC1A CDK5 CDK5 FBXW7 FBXW7 PTX3 PTX3 ASS1 ASS1 PROX1 PROX1 TIMELESS TIMELESS DDB1 DDB1 RACK1 RACK1 TEF TEF ADNP ADNP SGPL1 SGPL1 HNRNPD HNRNPD BHLHE41 BHLHE41 PRKAA1 PRKAA1 TIMP4 TIMP4 KISS1 KISS1 DBP DBP RAI1 RAI1 KDM5C KDM5C MTOR MTOR MAGEL2 MAGEL2 TRPM2 TRPM2 TYMS TYMS NUDT12 NUDT12 INHBA INHBA USP7 USP7 SRRD SRRD TH TH ID1 ID1 MAP2K6 MAP2K6 AHCY AHCY HDAC3 HDAC3 RESP18 RESP18 MAGED1 MAGED1 AXL AXL ENSPPAP00000029448 ENSPPAP00000029448 NTRK2 NTRK2 UBE3A UBE3A GAS2 GAS2 NMS NMS ENSPPAP00000029857 ENSPPAP00000029857 HNF4A HNF4A KDM2A KDM2A MAPK9 MAPK9 BTBD9 BTBD9 NDUFA9 NDUFA9 RORA RORA ENOX1 ENOX1 SIRT1 SIRT1 CLDN4 CLDN4 USP2 USP2 RORC RORC NAGLU NAGLU RORB RORB HLF HLF A2M A2M IGF1R IGF1R FBXL3 FBXL3 C3H3orf70 C3H3orf70 MTNR1A MTNR1A SIAH2 SIAH2 PGR PGR PER3 PER3 ENSPPAP00000010419 ENSPPAP00000010419 CGA CGA FBXW9 FBXW9 CASP2 CASP2 TP53 TP53 IMPDH2 IMPDH2 LGR4 LGR4 THRAP3 THRAP3 PPARG PPARG PPP1CB PPP1CB PAM PAM ZPBP2 ZPBP2 PTEN PTEN DDC DDC ENSPPAP00000012418 ENSPPAP00000012418 AFP AFP CLOCK CLOCK PML PML EGR3 EGR3 LOC100983911 LOC100983911 PRKCG PRKCG TNFAIP6 TNFAIP6 EGR1 EGR1 SPSB4 SPSB4 ENSPPAP00000013473 ENSPPAP00000013473 SLC6A4 SLC6A4 DRD2 DRD2 SUV39H1 SUV39H1 ENSPPAP00000030502 ENSPPAP00000030502 ENSPPAP00000030737 ENSPPAP00000030737 CREBBP CREBBP LOC100982721 LOC100982721 PRKDC PRKDC PROK2 PROK2 SRD5A1 SRD5A1 MTTP MTTP FSHB FSHB HNRNPU HNRNPU KDM8 KDM8 TPH1 TPH1 ROCK2 ROCK2 KLF9 KLF9 METTL3 METTL3 SCAPER SCAPER NOS3 NOS3 ARRB2 ARRB2 NR0B2 NR0B2 ATF4 ATF4 HTR7 HTR7 ADCY1 ADCY1 LOC100995377 LOC100995377 PPARA PPARA USP9X USP9X NGFR NGFR STAT5B STAT5B FZD4 FZD4 DNM1L DNM1L HEBP1 HEBP1 AGRP AGRP ARNTL2 ARNTL2 MMP2 MMP2 CDK1 CDK1 ENOX2 ENOX2 CBX3 CBX3 ATG7 ATG7 KAT2B KAT2B NCOR2 NCOR2 CARTPT CARTPT ENSPPAP00000035781 ENSPPAP00000035781 SRC SRC PER1 PER1 ENSPPAP00000036081 ENSPPAP00000036081 ENSPPAP00000036285 ENSPPAP00000036285 GSK3B GSK3B KDM5A KDM5A PTPRN PTPRN MTA1 MTA1 NAMPT NAMPT GPR176 GPR176 GABRB1 GABRB1 CCAR2 CCAR2 FBXW11 FBXW11 GDF10 GDF10 LOC100975187 LOC100975187 KDM5B KDM5B MYCBP2 MYCBP2 OPN4 OPN4 NFYA NFYA HCRTR2 HCRTR2 DDX5 DDX5 ENSPPAP00000039022 ENSPPAP00000039022 ENSPPAP00000039065 ENSPPAP00000039065 LOC100981710 LOC100981710 ROBO2 ROBO2 RPE65 RPE65 EREG EREG PASD1 PASD1 CREB1 CREB1 CIPC CIPC NOCT NOCT NR1D1 NR1D1 MAPK10 MAPK10 CAVIN3 CAVIN3 AANAT AANAT PER2 PER2 HSPA5 HSPA5 TOP1 TOP1 GFPT1 GFPT1 PPP1CC PPP1CC ADIPOQ ADIPOQ TOP2A TOP2A PRKAA2 PRKAA2 ENSPPAP00000042325 ENSPPAP00000042325 LOC100989599 LOC100989599 SLIT2 SLIT2 CIART CIART NFKB2 NFKB2 CDK5R1 CDK5R1 ENSPPAP00000015326 ENSPPAP00000015326 HAS2 HAS2 HUWE1 HUWE1 SUV39H2 SUV39H2 RELB RELB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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LOC100992554Nuclear receptor corepressor 1. (2259 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1068 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
LOC100986655GPS2_interact domain-containing protein. (211 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
MMP19Matrix metallopeptidase 19. (505 aa)
ZNF830Zinc finger protein 830. (392 aa)
ENSPPAP00000004673Uncharacterized protein. (176 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
CRTC1CREB regulated transcription coactivator 1. (622 aa)
SETXSenataxin. (2669 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
ENSPPAP00000001242BHLH domain-containing protein. (117 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
NKX2-1Uncharacterized protein. (126 aa)
PSPC1Paraspeckle component 1. (443 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
ENSPPAP00000003540Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (246 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1057 aa)
ENSPPAP00000013852RRM domain-containing protein. (161 aa)
GPR149G protein-coupled receptor 149. (731 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
CCDC90BCoiled-coil domain containing 90B. (254 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
ATF5Activating transcription factor 5. (281 aa)
ENSPPAP00000017065SER_THR_PHOSPHATASE domain-containing protein. (297 aa)
SP1Sp1 transcription factor. (786 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
HOMER1Homer scaffold protein 1. (358 aa)
NPAS2Neuronal PAS domain protein 2. (827 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ENSPPAP00000018727Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (486 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (759 aa)
NONONon-POU domain containing octamer binding. (471 aa)
ENSPPAP00000019077Uncharacterized protein. (54 aa)
EP300E1A binding protein p300. (2411 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1196 aa)
BHLHE40Basic helix-loop-helix family member e40. (414 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (510 aa)
PTNPleiotrophin. (172 aa)
ENSPPAP00000020094Uncharacterized protein. (65 aa)
PAX4Paired box 4. (351 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PIWIL2Uncharacterized protein; Belongs to the argonaute family. (974 aa)
SLIT3Slit guidance ligand 3. (1527 aa)
HES7BHLH domain-containing protein. (129 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (580 aa)
KLF10Kruppel like factor 10. (480 aa)
PROKR2Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
SFPQSplicing factor proline and glutamine rich. (709 aa)
NLGN1Neuroligin 1. (823 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
ENSPPAP00000004842Chromo domain-containing protein. (101 aa)
ENSPPAP00000004862Uncharacterized protein. (353 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
TNFRSF11ATNF receptor superfamily member 11a. (615 aa)
MDKMidkine. (143 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
MYBBP1AMYB binding protein 1a. (1338 aa)
ZFHX3Zinc finger homeobox 3. (3607 aa)
GPR157G protein-coupled receptor 157. (333 aa)
DHX9DExH-box helicase 9. (1270 aa)
AHRUncharacterized protein. (850 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (701 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
CUL4ACullin 4A; Belongs to the cullin family. (669 aa)
SIRT6Sirtuin 6. (355 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1196 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
LOC100975570Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
PTX3Pentraxin 3. (380 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
PROX1Prospero homeobox 1. (737 aa)
TIMELESSTimeless circadian regulator. (1208 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
TEFTEF transcription factor, PAR bZIP family member. (283 aa)
ADNPActivity dependent neuroprotector homeobox. (1102 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (349 aa)
BHLHE41Uncharacterized protein. (272 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
KISS1KiSS-1 metastasis suppressor. (138 aa)
DBPBZIP domain-containing protein. (188 aa)
RAI1Retinoic acid induced 1. (1917 aa)
KDM5CLysine demethylase 5C. (1560 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MAGEL2MAGE family member L2. (1221 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
TYMSThymidylate synthetase. (313 aa)
NUDT12Nudix hydrolase 12. (462 aa)
INHBAInhibin subunit beta A. (426 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1109 aa)
SRRDSRR1 domain containing. (317 aa)
THTyrosine hydroxylase. (528 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (155 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (447 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
RESP18Regulated endocrine specific protein 18. (228 aa)
MAGED1MAGE family member D1. (834 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
ENSPPAP00000029448Uncharacterized protein. (397 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (867 aa)
GAS2Growth arrest specific 2. (314 aa)
NMSNeuromedin S. (129 aa)
ENSPPAP00000029857Uncharacterized protein. (138 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
KDM2ALysine demethylase 2A. (1162 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
BTBD9BTB domain containing 9. (612 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
RORARAR related orphan receptor A. (559 aa)
ENOX1Ecto-NOX disulfide-thiol exchanger 1. (561 aa)
SIRT1Sirtuin 1. (693 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
RORCRAR related orphan receptor C. (525 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (682 aa)
RORBRAR related orphan receptor B. (482 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
IGF1RTyrosine-protein kinase receptor. (1389 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
C3H3orf70Uncharacterized protein. (214 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (271 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (636 aa)
PER3Period circadian regulator 3. (1211 aa)
ENSPPAP00000010419Uncharacterized protein. (355 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (147 aa)
FBXW9F-box and WD repeat domain containing 9. (478 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (935 aa)
THRAP3Thyroid hormone receptor associated protein 3. (954 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (974 aa)
ZPBP2Zona pellucida binding protein 2. (338 aa)
PTENUncharacterized protein. (542 aa)
DDCDopa decarboxylase. (489 aa)
ENSPPAP00000012418Uncharacterized protein. (412 aa)
AFPAlpha fetoprotein. (609 aa)
CLOCKClock circadian regulator. (847 aa)
PMLUncharacterized protein. (836 aa)
EGR3Early growth response 3. (387 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
ENSPPAP00000013473Uncharacterized protein. (518 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
ENSPPAP00000030502Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (849 aa)
ENSPPAP00000030737Uncharacterized protein. (408 aa)
CREBBPCREB binding protein. (2414 aa)
LOC100982721Uncharacterized protein. (245 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
PROK2Prokineticin 2. (119 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
MTTPMicrosomal triglyceride transfer protein. (921 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
KDM8Lysine demethylase 8. (454 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
KLF9Kruppel like factor 9. (244 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1392 aa)
NOS3Nitric oxide synthase 3. (997 aa)
ARRB2Arrestin beta 2. (447 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
ATF4Activating transcription factor 4. (340 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (480 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
LOC100995377Uncharacterized protein. (557 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2576 aa)
NGFRNerve growth factor receptor. (427 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
HEBP1Heme binding protein 1. (189 aa)
AGRPAgouti related neuropeptide. (132 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (624 aa)
MMP2Matrix metallopeptidase 2. (664 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ENOX2Ecto-NOX disulfide-thiol exchanger 2. (610 aa)
CBX3Uncharacterized protein. (183 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
KAT2BLysine acetyltransferase 2B. (675 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
CARTPTCART prepropeptide. (116 aa)
ENSPPAP00000035781AdoHcyase_NAD domain-containing protein. (405 aa)
SRCTyrosine-protein kinase. (458 aa)
PER1Period circadian regulator 1. (1290 aa)
ENSPPAP00000036081Uncharacterized protein. (302 aa)
ENSPPAP00000036285Uncharacterized protein. (393 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
KDM5ALysine demethylase 5A. (1643 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (973 aa)
MTA1Uncharacterized protein. (875 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (475 aa)
GPR176G protein-coupled receptor 176. (498 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
CCAR2Cell cycle and apoptosis regulator 2. (930 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
LOC100975187Uncharacterized protein. (446 aa)
KDM5BLysine demethylase 5B. (1580 aa)
MYCBP2MYC binding protein 2. (4751 aa)
OPN4Opsin 4. (499 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
ENSPPAP00000039022G_PROTEIN_RECEP_F1_2 domain-containing protein. (372 aa)
ENSPPAP00000039065Uncharacterized protein. (350 aa)
LOC100981710Uncharacterized protein. (389 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
EREGEpiregulin. (169 aa)
PASD1PAS domain containing repressor 1. (788 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CIPCCLOCK interacting pacemaker. (399 aa)
NOCTNocturnin. (394 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
CAVIN3Caveolae associated protein 3. (293 aa)
AANATAralkylamine N-acetyltransferase. (207 aa)
PER2Period circadian regulator 2. (1255 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (765 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (286 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1521 aa)
PRKAA2Non-specific serine/threonine protein kinase. (542 aa)
ENSPPAP00000042325Uncharacterized protein. (404 aa)
LOC100989599Uncharacterized protein; Belongs to the cytochrome P450 family. (339 aa)
SLIT2Slit guidance ligand 2. (1410 aa)
CIARTCircadian associated repressor of transcription. (385 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (351 aa)
ENSPPAP00000015326HECT domain-containing protein. (670 aa)
HAS2Hyaluronan synthase 2. (552 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4412 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)
RELBRELB proto-oncogene, NF-kB subunit. (537 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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