STRINGSTRING
NF1 NF1 COL8A1 COL8A1 RPGRIP1L RPGRIP1L NOTCH1 NOTCH1 ATF4 ATF4 FOXF2 FOXF2 FOXN4 FOXN4 TENM3 TENM3 AQP5 AQP5 MFSD2A MFSD2A MAN2A1 MAN2A1 NTRK2 NTRK2 LOC100975953 LOC100975953 IFT122 IFT122 MEIS1 MEIS1 TBC1D20 TBC1D20 OBSL1 OBSL1 DLL1 DLL1 TH TH RP1 RP1 CRB1 CRB1 YY1 YY1 IMPG2 IMPG2 GDF11 GDF11 HIPK1 HIPK1 ENSPPAP00000026779 ENSPPAP00000026779 STRA6 STRA6 ZEB1 ZEB1 CTNNB1 CTNNB1 ROM1 ROM1 PAX6 PAX6 MEGF11 MEGF11 TFAP2A TFAP2A HIPK2 HIPK2 TOPORS TOPORS PROX1 PROX1 KDM2B KDM2B RPGRIP1 RPGRIP1 JAG1 JAG1 AQP1 AQP1 IHH IHH BBS4 BBS4 TSPAN12 TSPAN12 PHACTR4 PHACTR4 SDK1 SDK1 FAT1 FAT1 EPHB2 EPHB2 PROM1 PROM1 CDON CDON BMP7 BMP7 ENSPPAP00000018389 ENSPPAP00000018389 AHI1 AHI1 COL8A2 COL8A2 NRL NRL NECTIN1 NECTIN1 NECTIN3 NECTIN3 TFAP2B TFAP2B CABP4 CABP4 TBX2 TBX2 ABI2 ABI2 CRB2 CRB2 SKI SKI BAX BAX THY1 THY1 NOTCH2 NOTCH2 LOC100983911 LOC100983911 BAK1 BAK1 SDK2 SDK2 ATP8A2 ATP8A2 ENSPPAP00000011900 ENSPPAP00000011900 BCAR3 BCAR3 SIX3 SIX3 BMP4 BMP4 USH1C USH1C HIF1A HIF1A THRB THRB WNT16 WNT16 SP3 SP3 MFN2 MFN2 FRS2 FRS2 LRP5 LRP5 SLC1A1 SLC1A1 WNT5A WNT5A GNAT2 GNAT2 RORB RORB NAGLU NAGLU ENSPPAP00000007855 ENSPPAP00000007855 PDE6C PDE6C WNT2B WNT2B ZHX2 ZHX2 TSKU TSKU EPHB1 EPHB1 TTC8 TTC8 PTPRM PTPRM RDH13 RDH13 IGFN1 IGFN1 LOC100980724 LOC100980724 DSCAM DSCAM ENSPPAP00000002562 ENSPPAP00000002562 EPHA2 EPHA2 PITX3 PITX3 PAX2 PAX2 RING1 RING1 FZD5 FZD5 CITED2 CITED2 GLI3 GLI3 IFT172 IFT172 KDR KDR RPE65 RPE65 CALB1 CALB1 ENSPPAP00000039593 ENSPPAP00000039593 ALDH1A3 ALDH1A3 FAT3 FAT3 FJX1 FJX1 HCN1 HCN1 IGSF22 IGSF22 TDRD7 TDRD7 RS1 RS1 LHX1 LHX1 PITX2 PITX2 STAT3 STAT3 WNT9A WNT9A VSX1 VSX1 CNTF CNTF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NF1Neurofibromin 1. (2839 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
RPGRIP1LRPGRIP1 like. (1309 aa)
NOTCH1Notch receptor 1. (2573 aa)
ATF4Activating transcription factor 4. (340 aa)
FOXF2Uncharacterized protein. (255 aa)
FOXN4Forkhead box N4. (512 aa)
TENM3Teneurin transmembrane protein 3. (2703 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (252 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
LOC100975953Uncharacterized protein. (678 aa)
IFT122Intraflagellar transport 122. (1292 aa)
MEIS1Homeobox domain-containing protein. (463 aa)
TBC1D20TBC1 domain family member 20. (402 aa)
OBSL1Obscurin like 1. (1862 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
THTyrosine hydroxylase. (528 aa)
RP1RP1 axonemal microtubule associated. (2152 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
YY1Uncharacterized protein. (370 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1243 aa)
GDF11Growth differentiation factor 11. (398 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
ENSPPAP00000026779Uncharacterized protein. (720 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
CTNNB1Catenin beta 1. (781 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
PAX6Uncharacterized protein. (467 aa)
MEGF11Multiple EGF like domains 11. (990 aa)
TFAP2ATF_AP-2 domain-containing protein. (328 aa)
HIPK2Protein kinase domain-containing protein. (954 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1044 aa)
PROX1Prospero homeobox 1. (737 aa)
KDM2BLysine demethylase 2B. (1336 aa)
RPGRIP1RPGR interacting protein 1. (1239 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (402 aa)
BBS4Bardet-Biedl syndrome 4. (547 aa)
TSPAN12Tetraspanin. (305 aa)
PHACTR4Phosphatase and actin regulator. (660 aa)
SDK1Sidekick cell adhesion molecule 1. (2113 aa)
FAT1FAT atypical cadherin 1. (4588 aa)
EPHB2EPH receptor B2. (1039 aa)
PROM1Prominin 1. (865 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ENSPPAP00000018389Uncharacterized protein. (112 aa)
AHI1Abelson helper integration site 1. (1240 aa)
COL8A2Collagen type VIII alpha 2 chain. (702 aa)
NRLNeural retina leucine zipper. (237 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
NECTIN3Nectin cell adhesion molecule 3. (504 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
CABP4Calcium binding protein 4. (275 aa)
TBX2T-box transcription factor 2. (622 aa)
ABI2Abl interactor 2. (513 aa)
CRB2Crumbs cell polarity complex component 2. (1083 aa)
SKISKI proto-oncogene. (666 aa)
BAXBCL2 associated X, apoptosis regulator. (218 aa)
THY1Thy-1 cell surface antigen. (161 aa)
NOTCH2Notch receptor 2. (2254 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
SDK2Sidekick cell adhesion molecule 2. (2172 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1162 aa)
ENSPPAP00000011900HMG box domain-containing protein. (291 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (826 aa)
SIX3Homeobox domain-containing protein. (264 aa)
BMP4TGF_BETA_2 domain-containing protein. (402 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
THRBUncharacterized protein. (476 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SP3Sp3 transcription factor. (721 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
LRP5LDL receptor related protein 5. (1839 aa)
SLC1A1Amino acid transporter. (524 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
RORBRAR related orphan receptor B. (482 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (682 aa)
ENSPPAP00000007855Uncharacterized protein. (192 aa)
PDE6CPhosphodiesterase. (858 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
EPHB1EPH receptor B1. (984 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
IGFN1Uncharacterized protein. (1240 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
DSCAMDS cell adhesion molecule. (1895 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
EPHA2EPH receptor A2. (976 aa)
PITX3Homeobox protein. (208 aa)
PAX2Paired box 2. (417 aa)
RING1E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...] (405 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
CITED2Uncharacterized protein. (179 aa)
GLI3GLI family zinc finger 3. (1580 aa)
IFT172Intraflagellar transport 172. (1767 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
CALB1Calbindin 1. (261 aa)
ENSPPAP00000039593Uncharacterized protein. (103 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
FAT3Uncharacterized protein. (892 aa)
FJX1Uncharacterized protein. (378 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (883 aa)
IGSF22Immunoglobulin superfamily member 22. (1326 aa)
TDRD7Tudor domain containing 7. (1077 aa)
RS1Retinoschisin 1. (224 aa)
LHX1LIM homeobox 1. (406 aa)
PITX2Homeobox protein. (354 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
VSX1Visual system homeobox 1. (365 aa)
CNTFCiliary neurotrophic factor. (200 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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