STRINGSTRING
EMX1 EMX1 PLA2G2A PLA2G2A PRDX1 PRDX1 RB1 RB1 NBEA NBEA DNAJA3 DNAJA3 ENSPPAP00000001242 ENSPPAP00000001242 ENSPPAP00000001268 ENSPPAP00000001268 RCOR1 RCOR1 PPP3CB PPP3CB P2RY14 P2RY14 ENSPPAP00000001715 ENSPPAP00000001715 POLB POLB CCR4 CCR4 ZNF251 ZNF251 IL7 IL7 MTHFD1 MTHFD1 MPL MPL ABCB10 ABCB10 LRRC19 LRRC19 TRIM10 TRIM10 UBAP2L UBAP2L DOCK10 DOCK10 RIPK3 RIPK3 FLT3 FLT3 GPR174 GPR174 HCLS1 HCLS1 MAEA MAEA IL20RB IL20RB P2RX7 P2RX7 JAK2 JAK2 EXT1 EXT1 TNFSF13B TNFSF13B ADA ADA CEBPG CEBPG GAPT GAPT ALAS2 ALAS2 ENSPPAP00000006569 ENSPPAP00000006569 RHEX RHEX LOC100969426 LOC100969426 ARHGEF5 ARHGEF5 TNFRSF13B TNFRSF13B ENSPPAP00000006969 ENSPPAP00000006969 LOC100973600 LOC100973600 GATA3 GATA3 TGFBR3 TGFBR3 RPS14 RPS14 PRDM14 PRDM14 ENSPPAP00000007855 ENSPPAP00000007855 SOD1 SOD1 RASSF2 RASSF2 DOCK11 DOCK11 SOS1 SOS1 PKNOX1 PKNOX1 GLIS2 GLIS2 ENSPPAP00000008803 ENSPPAP00000008803 GATA2 GATA2 ENSPPAP00000009275 ENSPPAP00000009275 ENSPPAP00000009313 ENSPPAP00000009313 ADGRG1 ADGRG1 BRD1 BRD1 UBA5 UBA5 ASXL1 ASXL1 ZC3H8 ZC3H8 ENSPPAP00000009712 ENSPPAP00000009712 FOXP3 FOXP3 MYCT1 MYCT1 LOC100988353 LOC100988353 SP3 SP3 SRF SRF BAP1 BAP1 JMJD6 JMJD6 BPGM BPGM HIF1A HIF1A BMP4 BMP4 LGR4 LGR4 SIT1 SIT1 VPS54 VPS54 BCR BCR BCL6 BCL6 TMOD3 TMOD3 CDK5RAP3 CDK5RAP3 PTH PTH SPTA1 SPTA1 TRAF3IP2 TRAF3IP2 FSTL1 FSTL1 ENSPPAP00000012520 ENSPPAP00000012520 CCN3 CCN3 BAK1 BAK1 LRRC45 LRRC45 CASP3 CASP3 ENSPPAP00000013382 ENSPPAP00000013382 WDR48 WDR48 FH FH SKIL SKIL TCIRG1 TCIRG1 G6PD G6PD PPP2R3C PPP2R3C NLRP6 NLRP6 MERTK MERTK LYN LYN NF1 NF1 FAM210B FAM210B ANXA1 ANXA1 SLC25A38 SLC25A38 EMCN EMCN PRDX5 PRDX5 KITLG KITLG KLHL10 KLHL10 ENSPPAP00000016807 ENSPPAP00000016807 EZH2 EZH2 SPNS2 SPNS2 TGFB1 TGFB1 CORO1A CORO1A JAM3 JAM3 NLE1 NLE1 MYB MYB BCL2 BCL2 ADAR ADAR HOXB6 HOXB6 SMO SMO XKR8 XKR8 GPR183 GPR183 ZNHIT1 ZNHIT1 ENSPPAP00000018941 ENSPPAP00000018941 NCSTN NCSTN ENSPPAP00000019366 ENSPPAP00000019366 KIT KIT TAL1 TAL1 PDE4B PDE4B CX3CR1 CX3CR1 SCNN1B SCNN1B RHAG RHAG DNASE2 DNASE2 ITPKB ITPKB PRDX2 PRDX2 ID2 ID2 TNFAIP3 TNFAIP3 KMT2E KMT2E ENSPPAP00000022875 ENSPPAP00000022875 FADD FADD MFHAS1 MFHAS1 IKZF1 IKZF1 ADGRF5 ADGRF5 GATA1 GATA1 F2R F2R CARD11 CARD11 AHSP AHSP SIVA1 SIVA1 ENSPPAP00000024034 ENSPPAP00000024034 TNFRSF17 TNFRSF17 ZFPM1 ZFPM1 KCNQ1 KCNQ1 SLC40A1 SLC40A1 ENSPPAP00000024845 ENSPPAP00000024845 NAPEPLD NAPEPLD AKT3 AKT3 PTPN11 PTPN11 IL6 IL6 NKX2-3 NKX2-3 SLC37A4 SLC37A4 FAS FAS LOC100991499 LOC100991499 ENSPPAP00000025722 ENSPPAP00000025722 RC3H2 RC3H2 HMOX1 HMOX1 SFXN1 SFXN1 LPCAT3 LPCAT3 ENSPPAP00000026327 ENSPPAP00000026327 ABL1 ABL1 SASH3 SASH3 EPAS1 EPAS1 ENSPPAP00000026779 ENSPPAP00000026779 LYAR LYAR CRISPLD1 CRISPLD1 SPI1 SPI1 DYRK3 DYRK3 IL2RA IL2RA INHBA INHBA LGALS2 LGALS2 SLC25A5 SLC25A5 ERCC2 ERCC2 ILDR2 ILDR2 FANCC FANCC TNFSF14 TNFSF14 CXCL6 CXCL6 SMAD5 SMAD5 LIPA LIPA OCIAD2 OCIAD2 ENSPPAP00000028807 ENSPPAP00000028807 CDH2 CDH2 ENSPPAP00000028953 ENSPPAP00000028953 LAT LAT ENSPPAP00000029143 ENSPPAP00000029143 FLVCR1 FLVCR1 RPS6 RPS6 AXL AXL CCNB2 CCNB2 THRA THRA CARD9 CARD9 PTBP3 PTBP3 GPAM GPAM KRAS KRAS TMEM14C TMEM14C SLC11A2 SLC11A2 ETV2 ETV2 SLC4A1 SLC4A1 BTK BTK NCKAP1L NCKAP1L PTPN2 PTPN2 GIGYF2 GIGYF2 IREB2 IREB2 AP3B1 AP3B1 LOC100990946 LOC100990946 NOS3 NOS3 SLC15A4 SLC15A4 ENSPPAP00000032591 ENSPPAP00000032591 RC3H1 RC3H1 KLF1 KLF1 PKN1 PKN1 MPIG6B MPIG6B MEF2C MEF2C NOTCH1 NOTCH1 IL7R IL7R HAMP HAMP STAT5B STAT5B ENSPPAP00000034005 ENSPPAP00000034005 SLC46A2 SLC46A2 BAX BAX RPS17 RPS17 GPI GPI ST6GALNAC1 ST6GALNAC1 AKT1 AKT1 MED1 MED1 BCL2L11 BCL2L11 SOS2 SOS2 SH2B3 SH2B3 ENSPPAP00000036378 ENSPPAP00000036378 JAK3 JAK3 ZBTB7A ZBTB7A RPS19 RPS19 SOX4 SOX4 L3MBTL3 L3MBTL3 ACIN1 ACIN1 DMTN DMTN NCAPG2 NCAPG2 SART3 SART3 C15orf41 C15orf41 TSPO2 TSPO2 ENSPPAP00000038499 ENSPPAP00000038499 GIMAP1 GIMAP1 ALAS1 ALAS1 EPO EPO CCR7 CCR7 ENSPPAP00000039636 ENSPPAP00000039636 FOXA3 FOXA3 ARID4A ARID4A CSF1 CSF1 CAMLG CAMLG INHA INHA ATP5IF1 ATP5IF1 CITED2 CITED2 HIPK2 HIPK2 UFL1 UFL1 FOXN1 FOXN1 SLC25A40 SLC25A40 RPS24 RPS24 HSPA9 HSPA9 RAG1 RAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EMX1Homeobox domain-containing protein. (178 aa)
PLA2G2APhospholipase A(2). (144 aa)
PRDX1Peroxiredoxin 1. (199 aa)
RB1RB transcriptional corepressor 1. (911 aa)
NBEANeurobeachin. (2943 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
ENSPPAP00000001242BHLH domain-containing protein. (117 aa)
ENSPPAP00000001268DHR-2 domain-containing protein; Belongs to the DOCK family. (503 aa)
RCOR1Uncharacterized protein. (434 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
P2RY14Purinergic receptor P2Y14. (338 aa)
ENSPPAP00000001715Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (470 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
ZNF251Zinc finger protein 251. (671 aa)
IL7Interleukin 7. (179 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (646 aa)
ABCB10ATP binding cassette subfamily B member 10. (609 aa)
LRRC19Leucine rich repeat containing 19. (370 aa)
TRIM10Tripartite motif containing 10. (475 aa)
UBAP2LUbiquitin associated protein 2 like. (1110 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2187 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
GPR174G protein-coupled receptor 174. (333 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
MAEACTLH domain-containing protein. (354 aa)
IL20RBInterleukin 20 receptor subunit beta. (281 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
ADAAdenosine deaminase. (412 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
GAPTGRB2 binding adaptor protein, transmembrane. (157 aa)
ALAS25-aminolevulinate synthase. (611 aa)
ENSPPAP00000006569Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (141 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
LOC100969426Uncharacterized protein. (135 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
TNFRSF13BTNF receptor superfamily member 13B. (293 aa)
ENSPPAP00000006969Uncharacterized protein. (584 aa)
LOC10097360040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (238 aa)
GATA3GATA binding protein 3. (444 aa)
TGFBR3Transforming growth factor beta receptor 3. (861 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
PRDM14PR/SET domain 14. (571 aa)
ENSPPAP00000007855Uncharacterized protein. (192 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
RASSF2Ras association domain family member 2. (326 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2073 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
PKNOX1PBX/knotted 1 homeobox 1. (435 aa)
GLIS2GLIS family zinc finger 2. (524 aa)
ENSPPAP00000008803Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (179 aa)
GATA2GATA binding protein 2. (480 aa)
ENSPPAP00000009275Uncharacterized protein. (269 aa)
ENSPPAP00000009313Uncharacterized protein. (501 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
BRD1Bromodomain containing 1. (1189 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
ASXL1ASXL transcriptional regulator 1. (1536 aa)
ZC3H8Zinc finger CCCH-type containing 8. (291 aa)
ENSPPAP0000000971240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (237 aa)
FOXP3Forkhead box P3. (441 aa)
MYCT1MYC target 1. (234 aa)
LOC100988353Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1012 aa)
SP3Sp3 transcription factor. (721 aa)
SRFSerum response factor. (414 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
BMP4TGF_BETA_2 domain-containing protein. (402 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (935 aa)
SIT1Signaling threshold regulating transmembrane adaptor 1. (196 aa)
VPS54VPS54 subunit of GARP complex. (976 aa)
BCRUncharacterized protein. (1034 aa)
BCL6BCL6 transcription repressor. (706 aa)
TMOD3Tropomodulin 3. (352 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (534 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2338 aa)
TRAF3IP2TRAF3 interacting protein 2. (573 aa)
FSTL1Follistatin like 1. (308 aa)
ENSPPAP0000001252040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (205 aa)
CCN3Cellular communication network factor 3. (357 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
ENSPPAP00000013382Uncharacterized protein. (901 aa)
WDR48WD repeat domain 48. (684 aa)
FHFumarate hydratase. (510 aa)
SKILSKI like proto-oncogene. (684 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
NLRP6NLR family pyrin domain containing 6. (892 aa)
MERTKMER proto-oncogene, tyrosine kinase. (966 aa)
LYNTyrosine-protein kinase. (526 aa)
NF1Neurofibromin 1. (2839 aa)
FAM210BDUF1279 domain-containing protein. (178 aa)
ANXA1Annexin. (346 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
EMCNEndomucin. (260 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
KLHL10Kelch like family member 10. (608 aa)
ENSPPAP00000016807Uncharacterized protein. (61 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
SPNS2Sphingolipid transporter 2. (480 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
NLE1Notchless homolog 1. (485 aa)
MYBMYB proto-oncogene, transcription factor. (768 aa)
BCL2BCL2 apoptosis regulator. (193 aa)
ADARA to I editase domain-containing protein. (193 aa)
HOXB6Homeobox B6. (224 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa)
XKR8XK-related protein. (354 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
ZNHIT1Zinc finger HIT-type containing 1. (154 aa)
ENSPPAP00000018941Uncharacterized protein. (121 aa)
NCSTNNicastrin. (709 aa)
ENSPPAP00000019366Uncharacterized protein. (154 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (291 aa)
PDE4BPhosphodiesterase. (736 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (685 aa)
RHAGRh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (441 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (360 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa)
PRDX2Peroxiredoxin 2. (198 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
TNFAIP3TNF alpha induced protein 3. (784 aa)
KMT2ELysine methyltransferase 2E. (1877 aa)
ENSPPAP00000022875Uncharacterized protein. (107 aa)
FADDDeath domain-containing protein. (144 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (969 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
GATA1GATA binding protein 1. (413 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
AHSPAlpha hemoglobin stabilizing protein. (102 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
ENSPPAP00000024034Uncharacterized protein. (541 aa)
TNFRSF17TNF receptor superfamily member 17. (184 aa)
ZFPM1Uncharacterized protein. (151 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
ENSPPAP0000002484540S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (211 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
IL6Uncharacterized protein. (198 aa)
NKX2-3Homeobox domain-containing protein. (303 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
FASFas cell surface death receptor. (335 aa)
LOC100991499Uncharacterized protein; Belongs to the heat shock protein 70 family. (640 aa)
ENSPPAP00000025722Uncharacterized protein. (132 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
SFXN1Sidoreflexin. (322 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
ENSPPAP00000026327Thioredoxin domain-containing protein. (188 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
ENSPPAP00000026779Uncharacterized protein. (720 aa)
LYARLy1 antibody reactive. (379 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
IL2RASushi domain-containing protein. (249 aa)
INHBAInhibin subunit beta A. (426 aa)
LGALS2Galectin. (136 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (620 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (543 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
CXCL6C-X-C motif chemokine. (114 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
OCIAD2OCIA domain containing 2. (154 aa)
ENSPPAP00000028807Thioredoxin domain-containing protein. (166 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
ENSPPAP00000028953Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (264 aa)
LATLinker for activation of T cells. (268 aa)
ENSPPAP00000029143Uncharacterized protein. (511 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (569 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (247 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
THRAUncharacterized protein. (617 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
PTBP3Polypyrimidine tract binding protein 3. (515 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
TMEM14CTransmembrane protein 14C. (112 aa)
SLC11A2Solute carrier family 11 member 2. (590 aa)
ETV2ETS variant 2. (342 aa)
SLC4A1Anion exchange protein. (906 aa)
BTKTyrosine-protein kinase. (693 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (424 aa)
GIGYF2GRB10 interacting GYF protein 2. (1325 aa)
IREB2Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
LOC100990946PA2c domain-containing protein. (147 aa)
NOS3Nitric oxide synthase 3. (997 aa)
SLC15A4Uncharacterized protein. (395 aa)
ENSPPAP00000032591Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (288 aa)
RC3H1Ring finger and CCCH-type domains 1. (1134 aa)
KLF1Kruppel like factor 1. (362 aa)
PKN1Protein kinase N1. (948 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (242 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
NOTCH1Notch receptor 1. (2573 aa)
IL7RInterleukin 7 receptor. (459 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
ENSPPAP00000034005Uncharacterized protein; Belongs to the cyclin family. (352 aa)
SLC46A2Solute carrier family 46 member 2. (475 aa)
BAXBCL2 associated X, apoptosis regulator. (218 aa)
RPS17Uncharacterized protein. (245 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (625 aa)
ST6GALNAC1ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (576 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa)
SH2B3SH2 domain-containing protein. (373 aa)
ENSPPAP00000036378Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (279 aa)
JAK3Tyrosine-protein kinase. (1090 aa)
ZBTB7AUncharacterized protein. (509 aa)
RPS19Ribosomal protein S19. (145 aa)
SOX4HMG box domain-containing protein. (251 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1339 aa)
DMTNDematin actin binding protein. (405 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
C15orf41Chromosome 15 open reading frame 41. (287 aa)
TSPO2Translocator protein 2. (170 aa)
ENSPPAP0000003849940S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (228 aa)
GIMAP1Uncharacterized protein. (500 aa)
ALAS15-aminolevulinate synthase. (640 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (372 aa)
ENSPPAP00000039636DUF1279 domain-containing protein. (209 aa)
FOXA3Forkhead box A3. (336 aa)
ARID4AAT-rich interaction domain 4A. (1259 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (106 aa)
CITED2Uncharacterized protein. (179 aa)
HIPK2Protein kinase domain-containing protein. (954 aa)
UFL1UFM1 specific ligase 1. (778 aa)
FOXN1Forkhead box N1. (648 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
RPS2440S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (289 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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