STRINGSTRING
BTNL8 BTNL8 PLEKHA1 PLEKHA1 ZAP70 ZAP70 ENSPPAP00000002380 ENSPPAP00000002380 IGLL1 IGLL1 CACNB3 CACNB3 CD3D CD3D BLK BLK SPG21 SPG21 TMEM269 TMEM269 CRKL CRKL FYB2 FYB2 IKBKG IKBKG ENSPPAP00000004994 ENSPPAP00000004994 ENSPPAP00000005092 ENSPPAP00000005092 MOG MOG NFAM1 NFAM1 VTCN1 VTCN1 MAPK1 MAPK1 EIF2B1 EIF2B1 ADA ADA VAV3 VAV3 CD3G CD3G ENSPPAP00000007520 ENSPPAP00000007520 EIF2B4 EIF2B4 GATA3 GATA3 ENSPPAP00000007704 ENSPPAP00000007704 PTPN6 PTPN6 MAP3K7 MAP3K7 CD276 CD276 ENSPPAP00000009755 ENSPPAP00000009755 RNF31 RNF31 FOXP3 FOXP3 KLHL6 KLHL6 PIK3CA PIK3CA UBE2N UBE2N CACNB4 CACNB4 CSK CSK PTPRJ PTPRJ ENSPPAP00000010626 ENSPPAP00000010626 HRAS HRAS BTN2A1 BTN2A1 CD19 CD19 ENSPPAP00000011445 ENSPPAP00000011445 DENND1B DENND1B LAX1 LAX1 BTN2A2 BTN2A2 TNFRSF21 TNFRSF21 TEC TEC THY1 THY1 LYN LYN EIF2B5 EIF2B5 INPP5D INPP5D SPPL3 SPPL3 THEMIS2 THEMIS2 LCK LCK EIF2B2 EIF2B2 ITK ITK CD3E CD3E PLCG1 PLCG1 BCL2 BCL2 BTNL3 BTNL3 CBLB CBLB MNDA MNDA BCAR1 BCAR1 RBCK1 RBCK1 EIF2B3 EIF2B3 PDE4B PDE4B HHLA2 HHLA2 SHB SHB THEMIS THEMIS IKBKB IKBKB PTPRC PTPRC PRKCB PRKCB ENSPPAP00000023019 ENSPPAP00000023019 LAT2 LAT2 NFKBIZ NFKBIZ CD28 CD28 BTNL9 BTNL9 KHDRBS1 KHDRBS1 WNK1 WNK1 LCP2 LCP2 PIK3CD PIK3CD FYN FYN BRAF BRAF RC3H2 RC3H2 PTPN22 PTPN22 ABL1 ABL1 CD38 CD38 ENSPPAP00000026998 ENSPPAP00000026998 ICOSLG ICOSLG SLA2 SLA2 PRKD2 PRKD2 MALT1 MALT1 TXK TXK SYK SYK LIME1 LIME1 BTN1A1 BTN1A1 MS4A1 MS4A1 BTNL2 BTNL2 LOC100993847 LOC100993847 CD79A CD79A BTK BTK PSEN1 PSEN1 ZNF683 ZNF683 NCKAP1L NCKAP1L ENSPPAP00000031691 ENSPPAP00000031691 NFKBID NFKBID ENSPPAP00000032530 ENSPPAP00000032530 RC3H1 RC3H1 SKAP1 SKAP1 BCL10 BCL10 MEF2C MEF2C PLCG2 PLCG2 FYB FYB BAX BAX BMX BMX BLNK BLNK MORN5 MORN5 NFATC2 NFATC2 PRAM1 PRAM1 FCHO1 FCHO1 CD79B CD79B ZC3H12A ZC3H12A STOML2 STOML2 HLA-DQB1 HLA-DQB1 HLA-DPB1 HLA-DPB1 CTLA4 CTLA4 PDE4D PDE4D LOC100986123 LOC100986123 BTN3A1 BTN3A1 LOC100987671 LOC100987671 CD8A CD8A TRAF6 TRAF6 ENSPPAP00000040700 ENSPPAP00000040700 CD247 CD247 LOC100983789 LOC100983789 ERMAP ERMAP RFTN1 RFTN1 RIPK2 RIPK2 STK11 STK11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTNL8Butyrophilin like 8. (500 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
ENSPPAP00000002380Uncharacterized protein. (575 aa)
IGLL1Ig-like domain-containing protein. (198 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (488 aa)
CD3DCD3d molecule. (171 aa)
BLKTyrosine-protein kinase. (505 aa)
SPG21SPG21 abhydrolase domain containing, maspardin. (303 aa)
TMEM269Transmembrane protein 269. (245 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
FYB2FYN binding protein 2. (640 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
ENSPPAP00000004994TNF receptor-associated factor. (475 aa)
ENSPPAP00000005092Uncharacterized protein. (582 aa)
MOGMyelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion. Belongs to the immunoglobulin superfamily. BTN/MOG family. (246 aa)
NFAM1NFAT activating protein with ITAM motif 1. (270 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
ADAAdenosine deaminase. (412 aa)
VAV3Vav guanine nucleotide exchange factor 3. (917 aa)
CD3GCD3g molecule. (182 aa)
ENSPPAP00000007520Uncharacterized protein. (398 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
GATA3GATA binding protein 3. (444 aa)
ENSPPAP00000007704Ig-like domain-containing protein. (190 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CD276Ig-like domain-containing protein. (280 aa)
ENSPPAP00000009755Ig-like domain-containing protein. (116 aa)
RNF31Uncharacterized protein. (1072 aa)
FOXP3Forkhead box P3. (441 aa)
KLHL6Kelch like family member 6. (621 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CSKTyrosine-protein kinase. (450 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1313 aa)
ENSPPAP00000010626Ig-like domain-containing protein. (215 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BTN2A1Butyrophilin subfamily 2 member A1. (526 aa)
CD19CD19 molecule. (545 aa)
ENSPPAP00000011445Ig-like domain-containing protein. (140 aa)
DENND1BDENN domain containing 1B. (775 aa)
LAX1Lymphocyte transmembrane adaptor 1. (398 aa)
BTN2A2Butyrophilin subfamily 2 member A2. (523 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
TECTyrosine-protein kinase. (631 aa)
THY1Thy-1 cell surface antigen. (161 aa)
LYNTyrosine-protein kinase. (526 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1189 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
THEMIS2Thymocyte selection associated family member 2. (643 aa)
LCKTyrosine-protein kinase. (524 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
ITKTyrosine-protein kinase. (620 aa)
CD3ECD3e molecule. (207 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa)
BCL2BCL2 apoptosis regulator. (193 aa)
BTNL3Butyrophilin like 3. (473 aa)
CBLBCbl proto-oncogene B. (982 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (438 aa)
PDE4BPhosphodiesterase. (736 aa)
HHLA2HERV-H LTR-associating 2. (414 aa)
SHBSH2 domain-containing protein. (285 aa)
THEMISThymocyte selection associated. (680 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1261 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
ENSPPAP00000023019IGv domain-containing protein. (93 aa)
LAT2Linker for activation of T cells family member 2. (243 aa)
NFKBIZNFKB inhibitor zeta. (706 aa)
CD28CD28 molecule. (220 aa)
BTNL9Butyrophilin like 9. (505 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FYNTyrosine-protein kinase. (537 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CD38CD38 molecule. (300 aa)
ENSPPAP00000026998Uncharacterized protein. (493 aa)
ICOSLGUncharacterized protein. (463 aa)
SLA2Src like adaptor 2. (261 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (826 aa)
MALT1MALT1 paracaspase. (786 aa)
TXKTyrosine-protein kinase. (527 aa)
SYKTyrosine-protein kinase. (635 aa)
LIME1Uncharacterized protein. (291 aa)
BTN1A1Butyrophilin subfamily 1 member A1. (526 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
BTNL2Ig-like domain-containing protein. (271 aa)
LOC100993847Ig-like domain-containing protein. (270 aa)
CD79ACD79a molecule. (226 aa)
BTKTyrosine-protein kinase. (693 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ZNF683Zinc finger protein 683. (524 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
ENSPPAP00000031691Ig-like domain-containing protein. (178 aa)
NFKBIDANK_REP_REGION domain-containing protein. (465 aa)
ENSPPAP00000032530Ig-like domain-containing protein. (108 aa)
RC3H1Ring finger and CCCH-type domains 1. (1134 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
BCL10CARD domain-containing protein. (316 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FYBSH3 domain-containing protein. (635 aa)
BAXBCL2 associated X, apoptosis regulator. (218 aa)
BMXTyrosine-protein kinase. (679 aa)
BLNKB cell linker. (417 aa)
MORN5MORN repeat containing 5. (161 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
PRAM1SH3 domain-containing protein. (830 aa)
FCHO1FCH domain only 1. (825 aa)
CD79BCD79b molecule. (229 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
STOML2Stomatin like 2. (361 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (261 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
PDE4DPhosphodiesterase. (706 aa)
LOC100986123Ig-like domain-containing protein. (154 aa)
BTN3A1Butyrophilin subfamily 3 member A1. (513 aa)
LOC100987671UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa)
CD8ACD8a molecule. (226 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
ENSPPAP00000040700UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
CD247CD247 molecule. (163 aa)
LOC100983789Uncharacterized protein. (612 aa)
ERMAPErythroblast membrane associated protein (Scianna blood group). (475 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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