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| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | ENSPPAP00000042406 | Uncharacterized protein. (234 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1312 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | PLPP3 | acidPPc domain-containing protein. (311 aa) |
| | SP100 | SP100 nuclear antigen. (857 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | LOC103782663 | Uncharacterized protein. (841 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (816 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | HIPK2 | Protein kinase domain-containing protein. (954 aa) |
| | TERF2IP | TERF2 interacting protein. (394 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1017 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | ENSPPAP00000040884 | Uncharacterized protein. (263 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (405 aa) |
| | ENSPPAP00000040700 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | CASP1-2 | CARD domain-containing protein. (95 aa) |
| | CAMK1D | Calcium/calmodulin dependent protein kinase ID. (315 aa) |
| | LOC100987671 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa) |
| | SLCO3A1 | Solute carrier organic anion transporter family member. (641 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | LOC100968388 | Uncharacterized protein. (273 aa) |
| | ENSPPAP00000039229 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa) |
| | ENSPPAP00000039228 | Eph LBD domain-containing protein. (350 aa) |
| | ENSPPAP00000039065 | Uncharacterized protein. (350 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | TRIM31 | Tripartite motif containing 31. (474 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (524 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | ENSPPAP00000037955 | BHLH domain-containing protein. (341 aa) |
| | S100A8 | Protein S100; Belongs to the S-100 family. (93 aa) |
| | MTPN | Myotrophin. (118 aa) |
| | MID2 | Midline 2. (733 aa) |
| | TRIML2 | Tripartite motif family like 2. (437 aa) |
| | LRP8 | LDL receptor related protein 8. (927 aa) |
| | ZBTB7A | Uncharacterized protein. (509 aa) |
| | STK3 | Serine/threonine kinase 3. (467 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | MYOCD | Myocardin. (986 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | ENSPPAP00000035595 | Uncharacterized protein. (261 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | TCF3 | Transcription factor 3. (673 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1977 aa) |
| | NKX6-1 | Homeobox domain-containing protein. (310 aa) |
| | TRIM15 | Tripartite motif containing 15. (465 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | LOC100971311 | Uncharacterized protein. (261 aa) |
| | TRIM13 | Tripartite motif containing 13. (410 aa) |
| | ENSPPAP00000033668 | Uncharacterized protein. (85 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (798 aa) |
| | ENSPPAP00000033446 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | LOC100995377 | Uncharacterized protein. (557 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | BCL10 | CARD domain-containing protein. (316 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | ZC4H2 | Zinc finger C4H2-type containing. (224 aa) |
| | DHX33 | DEAH-box helicase 33. (707 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | CYTL1 | Cytokine like 1. (136 aa) |
| | AR | Androgen receptor. (882 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) |
| | CDKN2A | Uncharacterized protein. (173 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1187 aa) |
| | TRIM37 | Tripartite motif containing 37. (964 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (988 aa) |
| | ENSPPAP00000029368 | Uncharacterized protein. (115 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | ENSPPAP00000028661 | Protein kinase C. (574 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (199 aa) |
| | MALT1 | MALT1 paracaspase. (786 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (826 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | EDA | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (223 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa) |
| | TRIML1 | Tripartite motif family like 1. (468 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | AIM2 | Absent in melanoma 2. (342 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | ENSPPAP00000027138 | Uncharacterized protein. (279 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) |
| | ENSPPAP00000026005 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa) |
| | TRIM68 | Tripartite motif containing 68. (485 aa) |
| | IL18R1 | Uncharacterized protein. (440 aa) |
| | EPHA5 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (370 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ENSPPAP00000024530 | Thioredoxin domain-containing protein. (217 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (997 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | RWDD1 | RWD domain containing 1. (243 aa) |
| | CRTC3 | CREB regulated transcription coactivator 3. (600 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | ENSPPAP00000023305 | DJ-1_PfpI domain-containing protein. (168 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa) |
| | RELN | Reelin. (3460 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (809 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) |
| | RGCC | Regulator of cell cycle. (137 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa) |
| | DDRGK1 | DDRGK domain containing 1. (314 aa) |
| | ITGB2 | Integrin beta. (806 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | ENSPPAP00000020965 | KH type-2 domain-containing protein. (250 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (986 aa) |
| | ZIC2 | Uncharacterized protein. (505 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | TRIM52 | Tripartite motif-containing protein 52. (293 aa) |
| | MBTPS2 | Membrane bound transcription factor peptidase, site 2. (525 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | RNF220 | Ring finger protein 220. (566 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | ENSPPAP00000019077 | Uncharacterized protein. (54 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | RTKN2 | Rhotekin 2. (609 aa) |
| | PPRC1 | PPARG related coactivator 1. (1637 aa) |
| | NTS | Neurotensin. (170 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | ENSPPAP00000018396 | MPN domain-containing protein. (188 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa) |
| | TSSK4 | Testis specific serine kinase 4. (338 aa) |
| | ESR2 | Estrogen receptor 2. (530 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1108 aa) |
| | ENSPPAP00000017817 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa) |
| | CRTC2 | CREB regulated transcription coactivator 2. (701 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | COPS5 | COP9 signalosome subunit 5. (333 aa) |
| | ENSPPAP00000016729 | Ribosomal_S3_C domain-containing protein. (100 aa) |
| | STING1 | Stimulator of interferon protein. (379 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | TFDP1 | Transcription factor. (411 aa) |
| | ANKRD42 | Ankyrin repeat domain 42. (527 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (855 aa) |
| | ABRA | Actin binding Rho activating protein. (381 aa) |
| | TRIM41 | Tripartite motif containing 41. (632 aa) |
| | TRIM8 | Tripartite motif containing 8. (446 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | TRAPPC9 | Trafficking protein particle complex 9. (1116 aa) |
| | DHX9 | DExH-box helicase 9. (1270 aa) |
| | CTH | Cystathionine gamma-lyase. (439 aa) |
| | PINK1 | PTEN induced kinase 1. (554 aa) |
| | EDN1 | Endothelin 1. (212 aa) |
| | CD200 | CD200 molecule. (294 aa) |
| | CLOCK | Clock circadian regulator. (847 aa) |
| | S100A9 | Protein S100; Belongs to the S-100 family. (114 aa) |
| | PRDX3 | Peroxiredoxin 3. (256 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | STK36 | Serine/threonine kinase 36. (1315 aa) |
| | MTDH | Metadherin. (567 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (599 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (772 aa) |
| | TRIM26 | Tripartite motif containing 26. (539 aa) |
| | PTEN | Uncharacterized protein. (542 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | ENSPPAP00000011964 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa) |
| | HSF1 | Heat shock transcription factor 1. (490 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | ENSPPAP00000011287 | Uncharacterized protein. (271 aa) |
| | NDP | Norrin cystine knot growth factor NDP. (133 aa) |
| | LOC100978286 | Uncharacterized protein. (249 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa) |
| | SRF | Serum response factor. (414 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (420 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) |
| | UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | ENSPPAP00000010058 | Uncharacterized protein. (165 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | ENSPPAP00000009428 | Uncharacterized protein. (295 aa) |
| | LRP5 | LDL receptor related protein 5. (1839 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (805 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | TAF12 | TFIID_20kDa domain-containing protein. (213 aa) |
| | NKX3-1 | NK3 homeobox 1. (223 aa) |
| | FANK1 | Fibronectin type III and ankyrin repeat domains 1. (344 aa) |
| | ENSPPAP00000008310 | Uncharacterized protein. (212 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (384 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | RNF25 | Ring finger protein 25. (476 aa) |
| | RIPK4 | Receptor interacting serine/threonine kinase 4. (834 aa) |
| | ADGRF1 | Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (910 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (540 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1597 aa) |
| | BEX1 | Brain expressed X-linked 1. (125 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (150 aa) |
| | UBE2V1-2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (615 aa) |
| | NHLH2 | Nescient helix-loop-helix 2. (135 aa) |
| | NFAM1 | NFAT activating protein with ITAM motif 1. (270 aa) |
| | CSF3 | Colony stimulating factor 3. (204 aa) |
| | ENSPPAP00000004994 | TNF receptor-associated factor. (475 aa) |
| | TFRC | Transferrin receptor. (773 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (711 aa) |
| | ENSPPAP00000004806 | Uncharacterized protein. (142 aa) |
| | JAK2 | Tyrosine-protein kinase. (1143 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | CARD14 | Caspase recruitment domain family member 14. (1001 aa) |
| | LOC100986336 | TIR domain-containing protein. (1033 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (484 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | PYDC5 | Pyrin domain-containing protein. (113 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | TICAM1 | RHIM domain-containing protein. (541 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1036 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1916 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) |
| | THAP11 | THAP domain containing 11. (309 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | IL10 | Interleukin 10. (178 aa) |
| | TIRAP | TIR domain-containing protein. (226 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | LOC100968508 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa) |
| | TNFSF18 | TNF superfamily member 18. (199 aa) |
| | CRTC1 | CREB regulated transcription coactivator 1. (622 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (297 aa) |
| | NEUROG1 | Neurogenin 1. (237 aa) |
