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| | EIF2AK2 | Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | ENSPPAP00000024530 | Thioredoxin domain-containing protein. (217 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | IL18R1 | Uncharacterized protein. (440 aa) |
| | TRIM68 | Tripartite motif containing 68. (485 aa) |
| | ENSPPAP00000026005 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | ENSPPAP00000027138 | Uncharacterized protein. (279 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | AIM2 | Absent in melanoma 2. (342 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | TRIML1 | Tripartite motif family like 1. (468 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa) |
| | EDA | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (223 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (826 aa) |
| | MALT1 | MALT1 paracaspase. (786 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (199 aa) |
| | ENSPPAP00000028661 | Protein kinase C. (574 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | TRIM37 | Tripartite motif containing 37. (964 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | AR | Androgen receptor. (882 aa) |
| | DHX33 | DEAH-box helicase 33. (707 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | BCL10 | CARD domain-containing protein. (316 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | ENSPPAP00000033446 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (798 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | ENSPPAP00000033668 | Uncharacterized protein. (85 aa) |
| | TRIM13 | Tripartite motif containing 13. (410 aa) |
| | LOC100971311 | Uncharacterized protein. (261 aa) |
| | TRIM15 | Tripartite motif containing 15. (465 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | ENSPPAP00000035595 | Uncharacterized protein. (261 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa) |
| | ZBTB7A | Uncharacterized protein. (509 aa) |
| | TRIML2 | Tripartite motif family like 2. (437 aa) |
| | MID2 | Midline 2. (733 aa) |
| | MTPN | Myotrophin. (118 aa) |
| | S100A8 | Protein S100; Belongs to the S-100 family. (93 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | ENSPPAP00000039065 | Uncharacterized protein. (350 aa) |
| | ENSPPAP00000039229 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa) |
| | LOC100968388 | Uncharacterized protein. (273 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | SLCO3A1 | Solute carrier organic anion transporter family member. (641 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa) |
| | LOC100987671 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa) |
| | CASP1-2 | CARD domain-containing protein. (95 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | ENSPPAP00000040700 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (405 aa) |
| | ENSPPAP00000040884 | Uncharacterized protein. (263 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1017 aa) |
| | TERF2IP | TERF2 interacting protein. (394 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (816 aa) |
| | LOC103782663 | Uncharacterized protein. (841 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1312 aa) |
| | ENSPPAP00000042406 | Uncharacterized protein. (234 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (297 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | TNFSF18 | TNF superfamily member 18. (199 aa) |
| | LOC100968508 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | TIRAP | TIR domain-containing protein. (226 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1036 aa) |
| | TICAM1 | RHIM domain-containing protein. (541 aa) |
| | PYDC5 | Pyrin domain-containing protein. (113 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC100986336 | TIR domain-containing protein. (1033 aa) |
| | CARD14 | Caspase recruitment domain family member 14. (1001 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | ENSPPAP00000004806 | Uncharacterized protein. (142 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (711 aa) |
| | TFRC | Transferrin receptor. (773 aa) |
| | ENSPPAP00000004994 | TNF receptor-associated factor. (475 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (615 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | UBE2V1-2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | RIPK4 | Receptor interacting serine/threonine kinase 4. (834 aa) |
| | RNF25 | Ring finger protein 25. (476 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa) |
| | ENSPPAP00000008310 | Uncharacterized protein. (212 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (805 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | ENSPPAP00000009428 | Uncharacterized protein. (295 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (420 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa) |
| | LOC100978286 | Uncharacterized protein. (249 aa) |
| | ENSPPAP00000011287 | Uncharacterized protein. (271 aa) |
| | ENSPPAP00000011964 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (772 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (599 aa) |
| | MTDH | Metadherin. (567 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | PRDX3 | Peroxiredoxin 3. (256 aa) |
| | S100A9 | Protein S100; Belongs to the S-100 family. (114 aa) |
| | CLOCK | Clock circadian regulator. (847 aa) |
| | CTH | Cystathionine gamma-lyase. (439 aa) |
| | DHX9 | DExH-box helicase 9. (1270 aa) |
| | TRAPPC9 | Trafficking protein particle complex 9. (1116 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa) |
| | TRIM8 | Tripartite motif containing 8. (446 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | ANKRD42 | Ankyrin repeat domain 42. (527 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | ENSPPAP00000016729 | Ribosomal_S3_C domain-containing protein. (100 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ENSPPAP00000017817 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | NTS | Neurotensin. (170 aa) |
| | RTKN2 | Rhotekin 2. (609 aa) |
| | ENSPPAP00000019077 | Uncharacterized protein. (54 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | TRIM52 | Tripartite motif-containing protein 52. (293 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (986 aa) |
| | ENSPPAP00000020965 | KH type-2 domain-containing protein. (250 aa) |
| | ITGB2 | Integrin beta. (806 aa) |
| | DDRGK1 | DDRGK domain containing 1. (314 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
