STRINGSTRING
PDLIM5 PDLIM5 SLC8A1 SLC8A1 GATA4 GATA4 ADPRHL1 ADPRHL1 IRX3 IRX3 MAML1 MAML1 CALR CALR WNT8A WNT8A IFT20 IFT20 GATA6 GATA6 CXADR CXADR TCAP TCAP SHOX2 SHOX2 LRRC10 LRRC10 C10orf113 C10orf113 VWA5B2 VWA5B2 SORBS2 SORBS2 SGCD SGCD MYL2 MYL2 NKX2-6 NKX2-6 MAP2K4 MAP2K4 MYLK3 MYLK3 SRF SRF TBX3 TBX3 BMP4 BMP4 TBX18 TBX18 TBX5 TBX5 NRG1 NRG1 MESP1 MESP1 MYH11 MYH11 BMP2 BMP2 MYO18B MYO18B NKX2-5 NKX2-5 CBY1 CBY1 FHOD3 FHOD3 ENSPPAP00000017681 ENSPPAP00000017681 ACTN2 ACTN2 KDM6B KDM6B WNT3A WNT3A LRRC10B LRRC10B WT1 WT1 ISL1 ISL1 HEY2 HEY2 SIRT6 SIRT6 NRAP NRAP CSRP3 CSRP3 ZMPSTE24 ZMPSTE24 TTN TTN MEF2A MEF2A PROX1 PROX1 TSC1 TSC1 SGCB SGCB ACADM ACADM FHL2 FHL2 MTOR MTOR VWA5A VWA5A ALPK3 ALPK3 BVES BVES ACVR1 ACVR1 OBSL1 OBSL1 ENSPPAP00000028441 ENSPPAP00000028441 PDGFRB PDGFRB MYH6 MYH6 ENSPPAP00000029665 ENSPPAP00000029665 LMNA LMNA RARB RARB ASB2 ASB2 ENSPPAP00000031014 ENSPPAP00000031014 ITGB1 ITGB1 HNRNPU HNRNPU VWA5B1 VWA5B1 MEF2C MEF2C BMPR1A BMPR1A AKAP13 AKAP13 CDK1 CDK1 ATG5 ATG5 NEBL NEBL MYOCD MYOCD CAV3 CAV3 BMP10 BMP10 PLEC PLEC ENSPPAP00000041190 ENSPPAP00000041190 NOX4 NOX4 ADRA1A ADRA1A SLC9A1 SLC9A1 RARA RARA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDLIM5PDZ and LIM domain 5. (625 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
GATA4GATA binding protein 4. (396 aa)
ADPRHL1Uncharacterized protein. (1764 aa)
IRX3Iroquois homeobox 3. (461 aa)
MAML1Mastermind like transcriptional coactivator 1. (911 aa)
CALRCalreticulin. (417 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
IFT20Intraflagellar transport 20. (158 aa)
GATA6Uncharacterized protein. (402 aa)
CXADRCXADR Ig-like cell adhesion molecule. (352 aa)
TCAPTitin-cap. (167 aa)
SHOX2Short stature homeobox 2. (355 aa)
LRRC10Leucine rich repeat containing 10. (277 aa)
C10orf113Chromosome 10 open reading frame 113. (155 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1242 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
SGCDSarcoglycan delta. (290 aa)
MYL2Myosin light chain 2. (166 aa)
NKX2-6NK2 homeobox 6. (302 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (371 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
SRFSerum response factor. (414 aa)
TBX3T-box transcription factor 3. (723 aa)
BMP4TGF_BETA_2 domain-containing protein. (402 aa)
TBX18T-box transcription factor 18. (607 aa)
TBX5T-box transcription factor 5. (518 aa)
NRG1Neuregulin 1. (645 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1802 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2567 aa)
NKX2-5NK2 homeobox 5. (325 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
FHOD3Formin homology 2 domain containing 3. (1567 aa)
ENSPPAP00000017681Myosin N-terminal SH3-like domain-containing protein. (161 aa)
ACTN2Actinin alpha 2. (872 aa)
KDM6BLysine demethylase 6B. (1680 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LRRC10BLeucine rich repeat containing 10B. (288 aa)
WT1Uncharacterized protein. (429 aa)
ISL1ISL LIM homeobox 1. (349 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SIRT6Sirtuin 6. (355 aa)
NRAPNebulin related anchoring protein. (1731 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (484 aa)
TTNUncharacterized protein. (27117 aa)
MEF2AMyocyte enhancer factor 2A. (505 aa)
PROX1Prospero homeobox 1. (737 aa)
TSC1TSC complex subunit 1. (1164 aa)
SGCBSarcoglycan beta. (334 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (453 aa)
FHL2Four and a half LIM domains 2. (279 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
VWA5AVon Willebrand factor A domain containing 5A. (786 aa)
ALPK3Alpha-type protein kinase domain-containing protein. (229 aa)
BVESBlood vessel epicardial substance. (360 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
OBSL1Obscurin like 1. (1862 aa)
ENSPPAP00000028441Uncharacterized protein. (543 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ENSPPAP00000029665Uncharacterized protein. (115 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
RARBRetinoic acid receptor beta. (448 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (625 aa)
ENSPPAP00000031014Protein kinase domain-containing protein. (371 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AKAP13A-kinase anchoring protein 13. (2813 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
NEBLNebulette. (1014 aa)
MYOCDMyocardin. (986 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
PLECPlectin. (4523 aa)
ENSPPAP00000041190SH3 domain-containing protein. (6597 aa)
NOX4Ferric oxidoreductase domain-containing protein. (285 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
RARAUncharacterized protein. (609 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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