STRINGSTRING
GPX1 GPX1 DMD DMD MYL10 MYL10 CACNB2 CACNB2 GSN GSN TNNI3 TNNI3 KCNE4 KCNE4 ATP1A2 ATP1A2 ABCC9 ABCC9 ENSPPAP00000023150 ENSPPAP00000023150 CSRP3 CSRP3 TTN TTN FGF12 FGF12 KCNJ5 KCNJ5 KCNQ1 KCNQ1 LOC100975396 LOC100975396 ATP1B1 ATP1B1 MTOR MTOR TAZ TAZ SCN5A SCN5A SCN1A SCN1A TNNC1 TNNC1 ENSPPAP00000027754 ENSPPAP00000027754 ENSPPAP00000028441 ENSPPAP00000028441 SMAD5 SMAD5 MYL4 MYL4 LOC100993131 LOC100993131 SCN3B SCN3B SCN2B SCN2B CACNA1C CACNA1C CDC42 CDC42 MYBPC3 MYBPC3 CAMK2D CAMK2D ENSPPAP00000015863 ENSPPAP00000015863 NKX2-5 NKX2-5 SCN1B SCN1B SGCZ SGCZ SNTA1 SNTA1 GRK2 GRK2 CACNA1G CACNA1G PIK3CA PIK3CA ACE ACE CASQ2 CASQ2 NEDD4L NEDD4L PKP2 PKP2 MYL2 MYL2 SGCD SGCD SLC1A1 SLC1A1 SOD1 SOD1 CACNA2D1 CACNA2D1 ENSPPAP00000006569 ENSPPAP00000006569 KCNE5 KCNE5 GAA GAA TNNI1 TNNI1 KCNE3 KCNE3 RANGRF RANGRF TCAP TCAP ENSPPAP00000004900 ENSPPAP00000004900 EXT1 EXT1 KCNE1 KCNE1 KCNJ3 KCNJ3 GATA6 GATA6 SGCG SGCG KCNJ2 KCNJ2 TPM1 TPM1 KCNE2 KCNE2 SLC8A1 SLC8A1 KCNN2 KCNN2 CACNA1D CACNA1D SLC9A1 SLC9A1 NUP155 NUP155 RYR2 RYR2 MAP2K6 MAP2K6 GPD1L GPD1L MYH6 MYH6 SCN4B SCN4B ANK2 ANK2 MYL3 MYL3 MYH7 MYH7 VEGFB VEGFB RPS6KA2 RPS6KA2 MYL7 MYL7 ENSPPAP00000033087 ENSPPAP00000033087 KCND3 KCND3 ATP1A1 ATP1A1 DNM1L DNM1L KCNJ8 KCNJ8 ATG5 ATG5 MYLK2 MYLK2 ENSPPAP00000036267 ENSPPAP00000036267 EXT2 EXT2 CAV3 CAV3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa)
DMDDystrophin. (3517 aa)
MYL10Myosin light chain 10. (226 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
GSNGelsolin. (784 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (221 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
ENSPPAP00000023150Uncharacterized protein. (75 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
TTNUncharacterized protein. (27117 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
LOC100975396Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (436 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1974 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
ENSPPAP00000027754Uncharacterized protein. (458 aa)
ENSPPAP00000028441Uncharacterized protein. (543 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
MYL4Myosin light chain 4. (193 aa)
LOC100993131Cell division control protein 42 homolog. (191 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
CDC42Uncharacterized protein. (191 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ENSPPAP00000015863Uncharacterized protein. (217 aa)
NKX2-5NK2 homeobox 5. (325 aa)
SCN1BIg-like domain-containing protein. (215 aa)
SGCZUncharacterized protein. (264 aa)
SNTA1Syntrophin alpha 1. (431 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (670 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2364 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
ACEAngiotensin-converting enzyme. (1223 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1080 aa)
PKP2Plakophilin 2. (862 aa)
MYL2Myosin light chain 2. (166 aa)
SGCDSarcoglycan delta. (290 aa)
SLC1A1Amino acid transporter. (524 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
ENSPPAP00000006569Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (141 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
TCAPTitin-cap. (167 aa)
ENSPPAP00000004900Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
KCNE1Uncharacterized protein. (132 aa)
KCNJ3Uncharacterized protein. (308 aa)
GATA6Uncharacterized protein. (402 aa)
SGCGSarcoglycan gamma. (291 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
KCNN2CaMBD domain-containing protein. (827 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
NUP155Nucleoporin 155. (1378 aa)
RYR2Ryanodine receptor 2. (4948 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
ANK2Ankyrin 2. (3957 aa)
MYL3Myosin light chain 3. (195 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (186 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
MYL7Myosin light chain 7. (148 aa)
ENSPPAP00000033087Uncharacterized protein. (751 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
ENSPPAP00000036267Glutathione peroxidase; Belongs to the glutathione peroxidase family. (139 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (891 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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