(21 nodes) Negative regulation of type I interferon-mediated signaling pathway network (Pan paniscus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	CACTIN	Cactin, spliceosome C complex subunit. (710 aa)
	TREX1	Three prime repair exonuclease 1. (369 aa)
	MMP12	Matrix metallopeptidase 12. (470 aa)
	ENSPPAP00000009956	Uncharacterized protein. (245 aa)
	OAS1	2',5'-oligoadenylate synthetase 1. (401 aa)
	ISG15	ISG15 ubiquitin like modifier. (165 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	DCST1	DC-STAMP domain containing 1. (706 aa)
	ADAR	A to I editase domain-containing protein. (193 aa)
	YTHDF2	YTH N6-methyladenosine RNA binding protein 2. (595 aa)
	NLRC5	NLR family CARD domain containing 5. (1865 aa)
	TTLL12	Tubulin tyrosine ligase like 12. (641 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7. (285 aa)
	SAMHD1	SAM domain and HD domain-containing protein 1. (626 aa)
	ENSPPAP00000031085	Uncharacterized protein. (277 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (424 aa)
	METTL3	Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
	ENSPPAP00000036339	Uncharacterized protein. (244 aa)
	STAT2	Signal transducer and activator of transcription. (853 aa)
	OAS3	2'-5'-oligoadenylate synthetase 3. (1082 aa)
	YTHDF3	YTH N6-methyladenosine RNA binding protein 3. (587 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	ISG15	ENSPPAP00000017853	ENSPPAP00000014623	A to I editase domain-containing protein.	ISG15 ubiquitin like modifier.	0.462
ADAR	OAS1	ENSPPAP00000017853	ENSPPAP00000013370	A to I editase domain-containing protein.	2',5'-oligoadenylate synthetase 1.	0.485
ADAR	OAS3	ENSPPAP00000017853	ENSPPAP00000040293	A to I editase domain-containing protein.	2'-5'-oligoadenylate synthetase 3.	0.449
ADAR	SAMHD1	ENSPPAP00000017853	ENSPPAP00000030664	A to I editase domain-containing protein.	SAM domain and HD domain-containing protein 1.	0.674
ADAR	STAT2	ENSPPAP00000017853	ENSPPAP00000038370	A to I editase domain-containing protein.	Signal transducer and activator of transcription.	0.622
ADAR	TREX1	ENSPPAP00000017853	ENSPPAP00000005543	A to I editase domain-containing protein.	Three prime repair exonuclease 1.	0.496
CNOT7	YTHDF2	ENSPPAP00000028144	ENSPPAP00000019114	CCR4-NOT transcription complex subunit 7.	YTH N6-methyladenosine RNA binding protein 2.	0.511
ENSPPAP00000009956	YTHDF2	ENSPPAP00000009956	ENSPPAP00000019114	Uncharacterized protein.	YTH N6-methyladenosine RNA binding protein 2.	0.511
ENSPPAP00000036339	YTHDF2	ENSPPAP00000036339	ENSPPAP00000019114	Uncharacterized protein.	YTH N6-methyladenosine RNA binding protein 2.	0.511
ISG15	ADAR	ENSPPAP00000014623	ENSPPAP00000017853	ISG15 ubiquitin like modifier.	A to I editase domain-containing protein.	0.462
ISG15	OAS1	ENSPPAP00000014623	ENSPPAP00000013370	ISG15 ubiquitin like modifier.	2',5'-oligoadenylate synthetase 1.	0.959
ISG15	OAS3	ENSPPAP00000014623	ENSPPAP00000040293	ISG15 ubiquitin like modifier.	2'-5'-oligoadenylate synthetase 3.	0.919
ISG15	SAMHD1	ENSPPAP00000014623	ENSPPAP00000030664	ISG15 ubiquitin like modifier.	SAM domain and HD domain-containing protein 1.	0.571
ISG15	STAT2	ENSPPAP00000014623	ENSPPAP00000038370	ISG15 ubiquitin like modifier.	Signal transducer and activator of transcription.	0.848
METTL3	YTHDF2	ENSPPAP00000032353	ENSPPAP00000019114	Methyltransferase like 3; Belongs to the MT-A70-like family.	YTH N6-methyladenosine RNA binding protein 2.	0.765
METTL3	YTHDF3	ENSPPAP00000032353	ENSPPAP00000041774	Methyltransferase like 3; Belongs to the MT-A70-like family.	YTH N6-methyladenosine RNA binding protein 3.	0.841
OAS1	ADAR	ENSPPAP00000013370	ENSPPAP00000017853	2',5'-oligoadenylate synthetase 1.	A to I editase domain-containing protein.	0.485
OAS1	ISG15	ENSPPAP00000013370	ENSPPAP00000014623	2',5'-oligoadenylate synthetase 1.	ISG15 ubiquitin like modifier.	0.959
OAS1	OAS3	ENSPPAP00000013370	ENSPPAP00000040293	2',5'-oligoadenylate synthetase 1.	2'-5'-oligoadenylate synthetase 3.	0.984
OAS1	SAMHD1	ENSPPAP00000013370	ENSPPAP00000030664	2',5'-oligoadenylate synthetase 1.	SAM domain and HD domain-containing protein 1.	0.456