STRINGSTRING
FGFR3 FGFR3 SP5 SP5 NEUROG1 NEUROG1 COL1A1 COL1A1 NAB1 NAB1 BMP6 BMP6 TIFAB TIFAB MATN1 MATN1 TMEM119 TMEM119 RAB23 RAB23 MMP16 MMP16 ENSPPAP00000003828 ENSPPAP00000003828 BMPR2 BMPR2 ACTN3 ACTN3 PHOSPHO2 PHOSPHO2 SCX SCX LTF LTF EXT1 EXT1 SHOX2 SHOX2 ACP5 ACP5 BMPR1B BMPR1B TSKU TSKU MEGF8 MEGF8 COL2A1 COL2A1 ATF2 ATF2 NPPC NPPC ENSPPAP00000009163 ENSPPAP00000009163 LRP5 LRP5 ENSPPAP00000009786 ENSPPAP00000009786 MMP13 MMP13 BMP4 BMP4 RARG RARG DCANP1 DCANP1 STC1 STC1 PEX7 PEX7 TRPV4 TRPV4 TBXT TBXT GLG1 GLG1 ALPL ALPL SKI SKI HAS2 HAS2 DLX5 DLX5 CYP26B1 CYP26B1 NAB2 NAB2 TGFB1 TGFB1 COL3A1 COL3A1 TGFB3 TGFB3 COL27A1 COL27A1 ANXA6 ANXA6 OSR2 OSR2 MSX1 MSX1 GNAS-2 GNAS-2 SFRP4 SFRP4 INSIG2 INSIG2 IHH IHH AXIN2 AXIN2 IFITM5 IFITM5 CDX1 CDX1 FREM1 FREM1 SCUBE2 SCUBE2 ENSPPAP00000023041 ENSPPAP00000023041 FGFR2 FGFR2 ZMPSTE24 ZMPSTE24 ATG9A ATG9A RIPPLY2 RIPPLY2 PAX1 PAX1 PAPPA2 PAPPA2 ATG9B ATG9B FOXN3 FOXN3 GHR GHR RUNX2 RUNX2 LTBP3 LTBP3 INSIG1 INSIG1 MMP14 MMP14 HOXA11 HOXA11 CER1 CER1 RARB RARB MEF2D MEF2D SMPD3 SMPD3 MEF2C MEF2C LRP5L LRP5L CHSY1 CHSY1 COMP COMP EXT2 EXT2 SERPINH1 SERPINH1 IFT80 IFT80 TMEM107 TMEM107 PHOSPHO1 PHOSPHO1 IMPAD1 IMPAD1 TRIP11 TRIP11 GLI3 GLI3 CITED2 CITED2 TFAP2A TFAP2A DHRS3 DHRS3 TGFBR2 TGFBR2 FGF18 FGF18 COL13A1 COL13A1 RARA RARA THBS3 THBS3 INPPL1 INPPL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR3Fibroblast growth factor receptor. (780 aa)
SP5Uncharacterized protein. (330 aa)
NEUROG1Neurogenin 1. (237 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
NAB1NGFI-A binding protein 1. (487 aa)
BMP6Bone morphogenetic protein 6. (453 aa)
TIFABTIFA inhibitor. (161 aa)
MATN1Matrilin 1. (496 aa)
TMEM119Transmembrane protein 119. (283 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
MMP16Matrix metallopeptidase 16. (609 aa)
ENSPPAP00000003828Fork-head domain-containing protein. (442 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
SCXBHLH domain-containing protein. (111 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SHOX2Short stature homeobox 2. (355 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
MEGF8Multiple EGF like domains 8. (2845 aa)
COL2A1Uncharacterized protein. (1313 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
NPPCNatriuretic peptide C. (126 aa)
ENSPPAP00000009163Uncharacterized protein. (232 aa)
LRP5LDL receptor related protein 5. (1839 aa)
ENSPPAP00000009786Homeobox domain-containing protein. (168 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
BMP4TGF_BETA_2 domain-containing protein. (402 aa)
RARGRetinoic acid receptor gamma. (464 aa)
DCANP1Dendritic cell associated nuclear protein. (237 aa)
STC1Stanniocalcin 1. (247 aa)
PEX7Peroxisomal biogenesis factor 7. (325 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
TBXTT-box transcription factor T. (435 aa)
GLG1Golgi glycoprotein 1. (1188 aa)
ALPLAlkaline phosphatase. (524 aa)
SKISKI proto-oncogene. (666 aa)
HAS2Hyaluronan synthase 2. (552 aa)
DLX5Distal-less homeobox 5. (289 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa)
NAB2NGFI-A binding protein 2. (525 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
COL3A1Collagen type III alpha 1 chain. (1465 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1838 aa)
ANXA6Annexin. (788 aa)
OSR2Odd-skipped related transciption factor 2. (433 aa)
MSX1Msh homeobox 1. (249 aa)
GNAS-2Uncharacterized protein. (245 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (402 aa)
AXIN2Axin 2. (843 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
CDX1Caudal type homeobox 1. (265 aa)
FREM1FRAS1 related extracellular matrix 1. (2179 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (980 aa)
ENSPPAP00000023041Uncharacterized protein. (426 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (484 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (848 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
PAX1Paired domain-containing protein. (438 aa)
PAPPA2Pappalysin 2. (1791 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (826 aa)
FOXN3Forkhead box N3. (490 aa)
GHRGrowth hormone receptor. (641 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1270 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
HOXA11Homeobox A11. (327 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
RARBRetinoic acid receptor beta. (448 aa)
MEF2DMyocyte enhancer factor 2D. (520 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (638 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
LRP5LLDL receptor related protein 5 like. (252 aa)
CHSY1Hexosyltransferase. (772 aa)
COMPCartilage oligomeric matrix protein. (762 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (891 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (215 aa)
IFT80Intraflagellar transport 80. (771 aa)
TMEM107Transmembrane protein 107. (146 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
IMPAD1Inositol monophosphatase domain containing 1. (357 aa)
TRIP11Thyroid hormone receptor interactor 11. (1979 aa)
GLI3GLI family zinc finger 3. (1580 aa)
CITED2Uncharacterized protein. (179 aa)
TFAP2ATF_AP-2 domain-containing protein. (328 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
RARAUncharacterized protein. (609 aa)
THBS3Thrombospondin 3. (956 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1253 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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