STRINGSTRING
SOX4 SOX4 BMPR2 BMPR2 NSD2 NSD2 TBX5 TBX5 NOTCH2 NOTCH2 TGFB2 TGFB2 NKX2-5 NKX2-5 SMO SMO HEY2 HEY2 TBX20 TBX20 ISL1 ISL1 ZFPM1 ZFPM1 CCN1 CCN1 GATA4 GATA4 ACVR1 ACVR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX4HMG box domain-containing protein. (251 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
TBX5T-box transcription factor 5. (518 aa)
NOTCH2Notch receptor 2. (2254 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
NKX2-5NK2 homeobox 5. (325 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TBX20Uncharacterized protein. (379 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ZFPM1Uncharacterized protein. (151 aa)
CCN1Cellular communication network factor 1. (381 aa)
GATA4GATA binding protein 4. (396 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.