STRINGSTRING
MYL6 MYL6 RB1 RB1 PPP3CB PPP3CB CFL2 CFL2 BTG2 BTG2 KEL KEL MYH15 MYH15 RTL1 RTL1 MEOX2 MEOX2 ANKRD33B ANKRD33B DISP1 DISP1 SCX SCX MYORG MYORG FOS FOS PITX1 PITX1 MYLPF MYLPF CHRNA1 CHRNA1 MYMX MYMX RTL5 RTL5 MYOZ1 MYOZ1 METTL21C METTL21C CFLAR CFLAR HLF HLF EMD EMD BARX2 BARX2 R3HDM1 R3HDM1 MAFF MAFF BCL9 BCL9 BIN3 BIN3 ENSPPAP00000010419 ENSPPAP00000010419 MYF5 MYF5 GTF3C5 GTF3C5 ENSPPAP00000011900 ENSPPAP00000011900 MYH14 MYH14 VAX1 VAX1 COPS2 COPS2 HEYL HEYL MYOG MYOG EGR1 EGR1 ATF3 ATF3 SKIL SKIL DES DES PEG10 PEG10 LOC100982721 LOC100982721 CNTNAP1 CNTNAP1 IGSF8 IGSF8 SRPK3 SRPK3 KLF5 KLF5 SIX4 SIX4 POPDC2 POPDC2 NF1 NF1 SKI SKI FLNB FLNB VAMP5 VAMP5 POPDC3 POPDC3 P2RX2 P2RX2 NR2F2 NR2F2 KLHL41 KLHL41 PAX5 PAX5 HLX HLX BCL2 BCL2 SELENON SELENON CASQ1 CASQ1 RXRG RXRG STAC3 STAC3 ZNF689 ZNF689 SMO SMO HOMER1 HOMER1 MYF6 MYF6 CDON CDON EP300 EP300 NUPR1 NUPR1 RYR1 RYR1 SHH SHH WNT3A WNT3A NPHS1 NPHS1 DMRTA2 DMRTA2 MED20 MED20 FGFRL1 FGFRL1 LMOD3 LMOD3 WT1 WT1 ACTA1 ACTA1 RCAN1 RCAN1 EOMES EOMES SMYD1 SMYD1 SAP30 SAP30 R3HDM2 R3HDM2 CSRP3 CSRP3 CDK5 CDK5 ASS1 ASS1 ANKRD1 ANKRD1 NR4A1 NR4A1 ZBTB18 ZBTB18 WNT10B WNT10B LEMD2 LEMD2 DAG1 DAG1 STRA6 STRA6 MSC MSC HOXD10 HOXD10 EGR2 EGR2 ITGA7 ITGA7 MYOD1 MYOD1 MYOZ2 MYOZ2 MTM1 MTM1 TAZ TAZ CAV1 CAV1 BVES BVES FOXN2 FOXN2 HIVEP3 HIVEP3 CCNT2 CCNT2 DLL1 DLL1 PHOX2B PHOX2B DNER DNER ENSPPAP00000029448 ENSPPAP00000029448 MYOM1 MYOM1 FXR1 FXR1 MEGF10 MEGF10 ENSPPAP00000030737 ENSPPAP00000030737 KRAS KRAS ASB2 ASB2 MEF2D MEF2D SPG11 SPG11 ENSPPAP00000032154 ENSPPAP00000032154 CHRND CHRND HOXD9 HOXD9 MEF2C MEF2C NOTCH1 NOTCH1 SIX1 SIX1 LARGE1 LARGE1 CACNA1S CACNA1S COL19A1 COL19A1 ENSPPAP00000035598 ENSPPAP00000035598 MYLK2 MYLK2 ENSPPAP00000036285 ENSPPAP00000036285 CNTFR CNTFR SVIL SVIL LOC100989544 LOC100989544 ENSPPAP00000037905 ENSPPAP00000037905 BCL9L BCL9L GPCPD1 GPCPD1 MAPK14 MAPK14 CAV2 CAV2 PLEC PLEC LOC100981710 LOC100981710 P2RX5 P2RX5 ENSPPAP00000039792 ENSPPAP00000039792 DMD DMD PPP3CA PPP3CA HMG20B HMG20B CITED2 CITED2 VGLL2 VGLL2 TCF21 TCF21 ENSPPAP00000042325 ENSPPAP00000042325 RIPOR2 RIPOR2 VRK3 VRK3 ANKRD33 ANKRD33 KLHL40 KLHL40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL6Uncharacterized protein. (207 aa)
RB1RB transcriptional corepressor 1. (911 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
KELKell metallo-endopeptidase (Kell blood group). (732 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1946 aa)
RTL1Retrotransposon Gag like 1. (1359 aa)
MEOX2Mesenchyme homeobox 2. (302 aa)
ANKRD33BANK_REP_REGION domain-containing protein. (416 aa)
DISP1Dispatched RND transporter family member 1. (1525 aa)
SCXBHLH domain-containing protein. (111 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PITX1Homeobox protein. (297 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (200 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (482 aa)
MYMXMyomixer, myoblast fusion factor. (84 aa)
RTL5Retrotrans_gag domain-containing protein. (402 aa)
MYOZ1Myozenin 1. (299 aa)
METTL21CMethyltransferase like 21C. (284 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
EMDEmerin. (254 aa)
BARX2BARX homeobox 2. (279 aa)
R3HDM1R3H domain containing 1. (1102 aa)
MAFFbZIP_Maf domain-containing protein. (129 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
BIN3Bridging integrator 3. (253 aa)
ENSPPAP00000010419Uncharacterized protein. (355 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
GTF3C5General transcription factor IIIC subunit 5. (528 aa)
ENSPPAP00000011900HMG box domain-containing protein. (291 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2030 aa)
VAX1Homeobox domain-containing protein. (186 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (327 aa)
MYOGMyogenin. (249 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
ATF3Activating transcription factor 3. (181 aa)
SKILSKI like proto-oncogene. (684 aa)
DESDesmin; Belongs to the intermediate filament family. (518 aa)
PEG10CCHC-type domain-containing protein. (766 aa)
LOC100982721Uncharacterized protein. (245 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
IGSF8Immunoglobulin superfamily member 8. (614 aa)
SRPK3SRSF protein kinase 3. (634 aa)
KLF5Uncharacterized protein. (366 aa)
SIX4SIX homeobox 4. (775 aa)
POPDC2Popeye domain containing 2. (368 aa)
NF1Neurofibromin 1. (2839 aa)
SKISKI proto-oncogene. (666 aa)
FLNBFilamin B. (2633 aa)
VAMP5Vesicle associated membrane protein 5. (116 aa)
POPDC3Popeye domain containing 3. (291 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (405 aa)
NR2F2Uncharacterized protein. (333 aa)
KLHL41Kelch like family member 41. (606 aa)
PAX5Paired box 5. (337 aa)
HLXH2.0 like homeobox. (493 aa)
BCL2BCL2 apoptosis regulator. (193 aa)
SELENONSelenoprotein N. (495 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
RXRGRetinoid X receptor gamma. (473 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
ZNF689Zinc finger protein 689. (500 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa)
HOMER1Homer scaffold protein 1. (358 aa)
MYF6Myogenic factor 6. (242 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
EP300E1A binding protein p300. (2411 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
RYR1Ryanodine receptor 1. (4924 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1244 aa)
DMRTA2DM domain-containing protein. (503 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
FGFRL1Fibroblast growth factor receptor like 1. (507 aa)
LMOD3Leiomodin 3. (560 aa)
WT1Uncharacterized protein. (429 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
RCAN1Regulator of calcineurin 1. (273 aa)
EOMESEomesodermin. (680 aa)
SMYD1SET and MYND domain containing 1. (497 aa)
SAP30Uncharacterized protein. (124 aa)
R3HDM2R3H domain containing 2. (1034 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
ZBTB18Zinc finger and BTB domain containing 18. (531 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LEMD2MSC domain-containing protein. (201 aa)
DAG1Dystroglycan 1. (895 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
MSCBHLH domain-containing protein. (295 aa)
HOXD10Homeobox D10. (410 aa)
EGR2Early growth response 2. (476 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
MYOZ2Myozenin 2. (264 aa)
MTM1Myotubularin 1. (603 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BVESBlood vessel epicardial substance. (360 aa)
FOXN2Forkhead box N2. (431 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2406 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
PHOX2BPaired like homeobox 2B. (282 aa)
DNERDelta/notch like EGF repeat containing. (645 aa)
ENSPPAP00000029448Uncharacterized protein. (397 aa)
MYOM1Myomesin 1. (1685 aa)
FXR1Uncharacterized protein. (782 aa)
MEGF10Multiple EGF like domains 10. (1140 aa)
ENSPPAP00000030737Uncharacterized protein. (408 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (625 aa)
MEF2DMyocyte enhancer factor 2D. (520 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
ENSPPAP00000032154Uncharacterized protein. (95 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (324 aa)
MEF2CMyocyte enhancer factor 2C. (482 aa)
NOTCH1Notch receptor 1. (2573 aa)
SIX1SIX homeobox 1. (284 aa)
LARGE1Uncharacterized protein. (286 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
COL19A1Collagen type XIX alpha 1 chain. (1130 aa)
ENSPPAP00000035598Uncharacterized protein. (205 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
ENSPPAP00000036285Uncharacterized protein. (393 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
SVILSupervillin. (2214 aa)
LOC100989544Uncharacterized protein. (116 aa)
ENSPPAP00000037905Uncharacterized protein. (608 aa)
BCL9LBCL9 like. (1483 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (677 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PLECPlectin. (4523 aa)
LOC100981710Uncharacterized protein. (389 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (431 aa)
ENSPPAP00000039792HP domain-containing protein. (133 aa)
DMDDystrophin. (3517 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
HMG20BHigh mobility group 20B. (317 aa)
CITED2Uncharacterized protein. (179 aa)
VGLL2Vestigial like family member 2. (275 aa)
TCF21Transcription factor 21. (179 aa)
ENSPPAP00000042325Uncharacterized protein. (404 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1068 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
ANKRD33ANK_REP_REGION domain-containing protein. (203 aa)
KLHL40Kelch like family member 40. (621 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (16%) [HD]