STRINGSTRING
GSKIP GSKIP FGFR2 FGFR2 PRKN PRKN LOC100975570 LOC100975570 ENSPPAP00000022866 ENSPPAP00000022866 DACT1 DACT1 NKD2 NKD2 BTRC BTRC SOSTDC1 SOSTDC1 DKK1 DKK1 ENSPPAP00000022416 ENSPPAP00000022416 SFRP1 SFRP1 DDIT3 DDIT3 ISL1 ISL1 AXIN2 AXIN2 TMEM170B TMEM170B CCNYL1 CCNYL1 LGR5 LGR5 ENSPPAP00000021459 ENSPPAP00000021459 CTNND2 CTNND2 SFRP4 SFRP4 SMAD3 SMAD3 DKK4 DKK4 WNT3A WNT3A SHH SHH ENSPPAP00000020305 ENSPPAP00000020305 AMER3 AMER3 AMER2 AMER2 WLS WLS RNF220 RNF220 ENSPPAP00000019393 ENSPPAP00000019393 TMEM64 TMEM64 APC APC USP34 USP34 HDAC1 HDAC1 PIN1 PIN1 SCYL2 SCYL2 NFKB1 NFKB1 NLE1 NLE1 CCDC88C CCDC88C ENSPPAP00000017361 ENSPPAP00000017361 FRZB FRZB TRPM4 TRPM4 RBX1 RBX1 TGFB1 TGFB1 SFRP5 SFRP5 OTULIN OTULIN CBY1 CBY1 SOX7 SOX7 AXIN1 AXIN1 DLX5 DLX5 NKX2-5 NKX2-5 PRDM15 PRDM15 HECW1 HECW1 SCEL SCEL FOXO1 FOXO1 KREMEN1 KREMEN1 FOLR1 FOLR1 BMP2 BMP2 FZD7 FZD7 PPM1N PPM1N MESP1 MESP1 TCF7L2 TCF7L2 EGR1 EGR1 ILK ILK TLE6 TLE6 SOX13 SOX13 TNKS TNKS ENSPPAP00000012290 ENSPPAP00000012290 RSPO2 RSPO2 LGR6 LGR6 LOC100981302 LOC100981302 DAPK3 DAPK3 XIAP XIAP DAB2 DAB2 INVS INVS ENSPPAP00000011329 ENSPPAP00000011329 TBX18 TBX18 LGR4 LGR4 ANKRD6 ANKRD6 GPC5 GPC5 CTHRC1 CTHRC1 FZD9 FZD9 GNAQ GNAQ LOC100996179 LOC100996179 TMEM198 TMEM198 SOX10 SOX10 UBAC2 UBAC2 SHISA3 SHISA3 DKKL1 DKKL1 CSNK1G3 CSNK1G3 SIAH2 SIAH2 GPRC5B GPRC5B CYLD CYLD JADE1 JADE1 G3BP1 G3BP1 CTNNBIP1 CTNNBIP1 STK4 STK4 EMD EMD ENSPPAP00000008445 ENSPPAP00000008445 ENSPPAP00000008364 ENSPPAP00000008364 WNT5A WNT5A TLE3 TLE3 FAM53B FAM53B MLLT3 MLLT3 LOC100968831 LOC100968831 TPBG TPBG SOX17 SOX17 EGF EGF COL1A1 COL1A1 PTPRU PTPRU LZTS2 LZTS2 MCC MCC SHISA6 SHISA6 FGF9 FGF9 BAMBI BAMBI TLE5 TLE5 USP47 USP47 NOG NOG RSPO3 RSPO3 IFT20 IFT20 WNT11 WNT11 AMER1 AMER1 OTULINL OTULINL APC2 APC2 ARNTL ARNTL SLC9A3R1 SLC9A3R1 GPC3 GPC3 SNAI2 SNAI2 ZNF703 ZNF703 USP8 USP8 NKD1 NKD1 FERMT1 FERMT1 CSNK1A1L CSNK1A1L VPS35 VPS35 MDK MDK LIMD1 LIMD1 PPP1CA PPP1CA DAAM2 DAAM2 CSNK1D CSNK1D RNF146 RNF146 ZEB2 ZEB2 NPHP4 NPHP4 MKS1 MKS1 CCNY CCNY EGFR EGFR STK11 STK11 ENSPPAP00000042479 ENSPPAP00000042479 PPM1B PPM1B ENSPPAP00000041589 ENSPPAP00000041589 SEMA5A SEMA5A LRP4 LRP4 LMBR1L LMBR1L RPS12 RPS12 LYPD6 LYPD6 GLI1 GLI1 OTUD5 OTUD5 GLI3 GLI3 ENSPPAP00000040749 ENSPPAP00000040749 YAP1 YAP1 SMURF2 SMURF2 PRICKLE1 PRICKLE1 TBL1XR1 TBL1XR1 CDK14 CDK14 CTNND1 CTNND1 ASPM ASPM RECK RECK RSPO1 RSPO1 RBPJ RBPJ FUZ FUZ DDX3X DDX3X MAPK14 MAPK14 DKK3 DKK3 TLE7 TLE7 ADGRA2 ADGRA2 CAPRIN2 CAPRIN2 SOX4 SOX4 GID8 GID8 PLEKHA4 PLEKHA4 WNK2 WNK2 CSNK1A1 CSNK1A1 AMFR AMFR CCAR2 CCAR2 DACT3 DACT3 SOX2 SOX2 LATS2 LATS2 GSK3B GSK3B STK3 STK3 JUP JUP LRRK2 LRRK2 UBR5 UBR5 ENSPPAP00000036211 ENSPPAP00000036211 VCP VCP SRC SRC TNKS2 TNKS2 TLE4 TLE4 IGFBP1 IGFBP1 CHD8 CHD8 RUVBL1 RUVBL1 ATP6AP2 ATP6AP2 ENSPPAP00000034340 ENSPPAP00000034340 LYPD6B LYPD6B FZD4 FZD4 TNN TNN NOTCH1 NOTCH1 PTK7 PTK7 ENSPPAP00000033311 ENSPPAP00000033311 FGF10 FGF10 PPP2R3A PPP2R3A DAB2IP DAB2IP WWTR1 WWTR1 SOST SOST CDH3 CDH3 PSEN1 PSEN1 TMEM9 TMEM9 KPNA1 KPNA1 TLE2 TLE2 LRRK1 LRRK1 RUVBL2 RUVBL2 DKK2 DKK2 ENSPPAP00000029955 ENSPPAP00000029955 ENSPPAP00000029665 ENSPPAP00000029665 JRK JRK NPPA NPPA CDH2 CDH2 TTC21B TTC21B PFDN5 PFDN5 EDA EDA TLE1 TLE1 LOC106634746 LOC106634746 CAV1 CAV1 GSK3A GSK3A CSNK1G1 CSNK1G1 RBMS3 RBMS3 NOTUM NOTUM FRMD8 FRMD8 ENSPPAP00000025987 ENSPPAP00000025987 HHEX HHEX LATS1 LATS1 PTPRO PTPRO TMEM131L TMEM131L PPM1A PPM1A WNK1 WNK1 TMEM88 TMEM88 WNT10B WNT10B MAD2L2 MAD2L2 CTDNEP1 CTDNEP1 DRAXIN DRAXIN CTNNB1 CTNNB1 FZD6 FZD6 ENSPPAP00000024044 ENSPPAP00000024044 BICC1 BICC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSKIPGSK3B interacting protein. (147 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (428 aa)
LOC100975570Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
ENSPPAP00000022866Uncharacterized protein. (127 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (750 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (416 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (289 aa)
ENSPPAP00000022416Uncharacterized protein. (68 aa)
SFRP1NTR domain-containing protein. (178 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
ISL1ISL LIM homeobox 1. (349 aa)
AXIN2Axin 2. (843 aa)
TMEM170BTransmembrane protein 170B. (132 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
ENSPPAP00000021459Cyclin N-terminal domain-containing protein. (350 aa)
CTNND2Uncharacterized protein. (817 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
ENSPPAP00000020305Uncharacterized protein. (256 aa)
AMER3APC membrane recruitment protein 3. (861 aa)
AMER2Uncharacterized protein. (466 aa)
WLSWnt ligand secretion mediator. (541 aa)
RNF220Ring finger protein 220. (566 aa)
ENSPPAP00000019393Protein kinase domain-containing protein. (777 aa)
TMEM64Transmembrane protein 64. (320 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3536 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (145 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
NLE1Notchless homolog 1. (485 aa)
CCDC88CCoiled-coil domain containing 88C. (2019 aa)
ENSPPAP00000017361Uncharacterized protein. (81 aa)
FRZBFrizzled related protein. (325 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1138 aa)
RBX1Ring-box 1. (108 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SFRP5Secreted frizzled related protein 5. (311 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (342 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
SOX7Uncharacterized protein. (338 aa)
AXIN1Axin 1. (862 aa)
DLX5Distal-less homeobox 5. (289 aa)
NKX2-5NK2 homeobox 5. (325 aa)
PRDM15PR/SET domain 15. (1469 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1602 aa)
SCELSciellin. (688 aa)
FOXO1Fork-head domain-containing protein. (527 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (470 aa)
FOLR1Folate receptor alpha. (257 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
PPM1NPP2C_C domain-containing protein. (130 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
TCF7L2Transcription factor 7 like 2. (555 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
ILKIntegrin linked kinase. (533 aa)
TLE6TLE family member 6, subcortical maternal complex member. (538 aa)
SOX13SRY-box transcription factor 13. (622 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
ENSPPAP00000012290Uncharacterized protein. (285 aa)
RSPO2R-spondin 2. (243 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (961 aa)
LOC100981302FERM domain-containing protein. (452 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
DAB2DAB adaptor protein 2. (752 aa)
INVSInversin. (1029 aa)
ENSPPAP00000011329FCP1 homology domain-containing protein. (218 aa)
TBX18T-box transcription factor 18. (607 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (935 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (517 aa)
GNAQG protein subunit alpha q. (313 aa)
LOC100996179CYCLIN domain-containing protein. (360 aa)
TMEM198Transmembrane protein 198. (360 aa)
SOX10SRY-box transcription factor 10. (466 aa)
UBAC2UBA domain containing 2. (344 aa)
SHISA3Shisa family member 3. (238 aa)
DKKL1Dickkopf like acrosomal protein 1. (242 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (271 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (421 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
JADE1Jade family PHD finger 1. (857 aa)
G3BP1G3BP stress granule assembly factor 1. (466 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
STK4Serine/threonine kinase 4. (487 aa)
EMDEmerin. (254 aa)
ENSPPAP00000008445TLE_N domain-containing protein. (90 aa)
ENSPPAP00000008364Peptidyl-prolyl cis-trans isomerase. (155 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
TLE3TLE family member 3, transcriptional corepressor. (774 aa)
FAM53BFamily with sequence similarity 53 member B. (422 aa)
MLLT3MLLT3 super elongation complex subunit. (566 aa)
LOC100968831Uncharacterized protein. (212 aa)
TPBGTrophoblast glycoprotein. (419 aa)
SOX17SRY-box transcription factor 17. (428 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1296 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
MCCMCC regulator of WNT signaling pathway. (910 aa)
SHISA6Shisa family member 6. (461 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
TLE5TLE family member 5, transcriptional modulator. (264 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
RSPO3R-spondin 3. (291 aa)
IFT20Intraflagellar transport 20. (158 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (356 aa)
APC2Uncharacterized protein. (1779 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ZNF703Zinc finger protein 703. (482 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
NKD1EF-hand domain-containing protein. (634 aa)
FERMT1Fermitin family member 1. (677 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
MDKMidkine. (143 aa)
LIMD1LIM domains containing 1. (676 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
RNF146Ring finger protein 146. (359 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
NPHP4Nephrocystin 4. (1426 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
ENSPPAP0000004247940S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (138 aa)
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
ENSPPAP00000041589DUF4203 domain-containing protein. (106 aa)
SEMA5ASemaphorin 5A. (1074 aa)
LRP4LDL receptor related protein 4. (1857 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
RPS1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
LYPD6LY6/PLAUR domain containing 6. (171 aa)
GLI1GLI family zinc finger 1. (1106 aa)
OTUD5OTU domain-containing protein. (349 aa)
GLI3GLI family zinc finger 3. (1580 aa)
ENSPPAP0000004074940S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
YAP1Yes associated protein 1. (512 aa)
SMURF2E3 ubiquitin-protein ligase. (790 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (545 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
CTNND1Catenin delta 1. (975 aa)
ASPMAbnormal spindle microtubule assembly. (3477 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (970 aa)
RSPO1R-spondin 1. (267 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (499 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
TLE7TLE family member 7. (414 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1306 aa)
CAPRIN2Caprin family member 2. (1094 aa)
SOX4HMG box domain-containing protein. (251 aa)
GID8GID complex subunit 8 homolog. (228 aa)
PLEKHA4Pleckstrin homology domain containing A4. (779 aa)
WNK2WNK lysine deficient protein kinase 2. (2240 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
AMFRAutocrine motility factor receptor. (564 aa)
CCAR2Cell cycle and apoptosis regulator 2. (930 aa)
DACT3Uncharacterized protein. (180 aa)
SOX2SRY-box transcription factor 2. (299 aa)
LATS2Non-specific serine/threonine protein kinase. (1088 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
STK3Serine/threonine kinase 3. (467 aa)
JUPJunction plakoglobin. (745 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2757 aa)
ENSPPAP00000036211Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (920 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
SRCTyrosine-protein kinase. (458 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
TLE4TLE family member 4, transcriptional corepressor. (790 aa)
IGFBP1Insulin like growth factor binding protein 1. (275 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2573 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
ENSPPAP00000034340NTF2 domain-containing protein. (394 aa)
LYPD6BLY6/PLAUR domain containing 6B. (241 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
TNNTenascin N. (1299 aa)
NOTCH1Notch receptor 1. (2573 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
ENSPPAP00000033311Protein kinase domain-containing protein. (305 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
SOSTSclerostin. (213 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
TMEM9Transmembrane protein 9. (183 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
TLE2TLE family member 2, transcriptional corepressor. (606 aa)
LRRK1Leucine rich repeat kinase 1. (2015 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
ENSPPAP0000002995540S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (148 aa)
ENSPPAP00000029665Uncharacterized protein. (115 aa)
JRKJrk helix-turn-helix protein. (556 aa)
NPPANatriuretic peptide A. (153 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
PFDN5Prefoldin subunit 5. (154 aa)
EDATNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (223 aa)
TLE1TLE family member 1, transcriptional corepressor. (779 aa)
LOC106634746Uncharacterized protein. (211 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (463 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa)
RBMS3RNA binding motif single stranded interacting protein 3. (437 aa)
NOTUMUncharacterized protein. (252 aa)
FRMD8FERM domain containing 8. (464 aa)
ENSPPAP0000002598740S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (129 aa)
HHEXHematopoietically expressed homeobox. (255 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
TMEM131LTransmembrane 131 like. (1617 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
TMEM88Transmembrane protein 88. (159 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
CTNNB1Catenin beta 1. (781 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
ENSPPAP00000024044PPM-type phosphatase domain-containing protein. (75 aa)
BICC1BicC family RNA binding protein 1. (959 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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