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| | JAK2 | Tyrosine-protein kinase. (1143 aa) |
| | ENSPPAP00000004558 | Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (161 aa) |
| | LOC100980724 | BZIP domain-containing protein. (359 aa) |
| | ENSPPAP00000004806 | Uncharacterized protein. (142 aa) |
| | ENSPPAP00000004989 | Aldo_ket_red domain-containing protein. (269 aa) |
| | OXR1 | Oxidation resistance 1. (872 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa) |
| | TREX1 | Three prime repair exonuclease 1. (369 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1472 aa) |
| | MSRA | PMSR domain-containing protein. (239 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (706 aa) |
| | SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) |
| | MGAT3 | Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (533 aa) |
| | ENSPPAP00000006569 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (141 aa) |
| | ENSPPAP00000006687 | Protein kinase domain-containing protein. (379 aa) |
| | STK25 | Serine/threonine kinase 25. (426 aa) |
| | ROMO1 | Reactive oxygen species modulator 1. (79 aa) |
| | SIRT1 | Sirtuin 1. (693 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa) |
| | FANCD2 | FA complementation group D2. (1259 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | MGMT | O-6-methylguanine-DNA methyltransferase. (238 aa) |
| | LOC100969990 | Uncharacterized protein. (659 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (805 aa) |
| | RNF112 | Ring finger protein 112. (631 aa) |
| | ETV5 | ETS variant 5. (510 aa) |
| | WNK3 | WNK lysine deficient protein kinase 3. (1800 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa) |
| | ZNF622 | Zinc finger protein 622. (477 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | OXSR1 | Oxidative stress responsive kinase 1. (527 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | ADNP2 | ADNP homeobox 2. (1125 aa) |
| | CAB39 | Calcium binding protein 39. (341 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1552 aa) |
| | SESN2 | Sestrin 2. (480 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | HSF1 | Heat shock transcription factor 1. (490 aa) |
| | ENSPPAP00000011964 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa) |
| | SIRPB1 | Uncharacterized protein. (427 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | DAPK1 | Death associated protein kinase 1. (1440 aa) |
| | LRRC8E | Leucine rich repeat containing 8 VRAC subunit E. (796 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (809 aa) |
| | ANKRD2 | Ankyrin repeat domain 2. (360 aa) |
| | STAU2 | Staufen double-stranded RNA binding protein 2. (608 aa) |
| | ENSPPAP00000023190 | Aldo_ket_red domain-containing protein. (294 aa) |
| | ENSPPAP00000023305 | DJ-1_PfpI domain-containing protein. (168 aa) |
| | LRRC8C | Leucine rich repeat containing 8 VRAC subunit C. (773 aa) |
| | RWDD1 | RWD domain containing 1. (243 aa) |
| | ERCC6L2 | ERCC excision repair 6 like 2. (712 aa) |
| | GSKIP | GSK3B interacting protein. (147 aa) |
| | STOX1 | Storkhead box 1. (885 aa) |
| | GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa) |
| | ENSPPAP00000024161 | Aldo_ket_red domain-containing protein. (232 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (997 aa) |
| | AGAP3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (876 aa) |
| | PRDX3 | Peroxiredoxin 3. (256 aa) |
| | PML | Uncharacterized protein. (836 aa) |
| | STAT6 | Signal transducer and activator of transcription. (852 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | LOC100983911 | BZIP domain-containing protein. (318 aa) |
| | ZNF277 | Zinc finger protein 277. (456 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) |
| | MYLK | Myosin light chain kinase. (1847 aa) |
| | EDN1 | Endothelin 1. (212 aa) |
| | PINK1 | PTEN induced kinase 1. (554 aa) |
| | G6PD | Glucose-6-phosphate dehydrogenase. (560 aa) |
| | ALDH3B1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (403 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | OSER1 | Oxidative stress responsive serine rich 1. (292 aa) |
| | CRYGD | Crystallin gamma D; Belongs to the beta/gamma-crystallin family. (174 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | SIRPA | Signal regulatory protein alpha. (504 aa) |
| | STX2 | Syntaxin 2; Belongs to the syntaxin family. (278 aa) |
| | SRXN1 | Sulfiredoxin. (137 aa) |
| | FOXO1 | Fork-head domain-containing protein. (527 aa) |
| | PYROXD1 | Pyridine nucleotide-disulphide oxidoreductase domain 1. (500 aa) |
| | NME8 | NME/NM23 family member 8. (588 aa) |
| | SELENOS | Uncharacterized protein. (218 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (537 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (788 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | PRDX5 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa) |
| | SLC25A24 | Solute carrier family 25 member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa) |
| | ENSPPAP00000016729 | Ribosomal_S3_C domain-containing protein. (100 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | GSR | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa) |
| | ENSPPAP00000024530 | Thioredoxin domain-containing protein. (217 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | RCSD1 | RCSD domain containing 1. (427 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1195 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | CAMKK2 | Calcium/calmodulin dependent protein kinase kinase 2. (588 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | ENSPPAP00000026005 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | ENSPPAP00000026327 | Thioredoxin domain-containing protein. (188 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (870 aa) |
| | SLC8A1 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) |
| | PRDX1 | Peroxiredoxin 1. (199 aa) |
| | SETX | Senataxin. (2669 aa) |
| | AMBP | Alpha-1-microglobulin/bikunin precursor. (364 aa) |
| | PLEKHA1 | Pleckstrin homology domain containing A1. (404 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | LOC100968508 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | PAX2 | Paired box 2. (417 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TPM1 | Uncharacterized protein; Belongs to the tropomyosin family. (326 aa) |
| | CPEB2 | Uncharacterized protein. (547 aa) |
| | DIABLO | Uncharacterized protein. (239 aa) |
| | AKR1B1 | Aldo-keto reductase family 1 member B. (263 aa) |
| | ENSPPAP00000002562 | BZIP domain-containing protein. (314 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (417 aa) |
| | STK24 | Serine/threonine kinase 24. (443 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (628 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | NET1 | Neuroepithelial cell transforming 1. (603 aa) |
| | ENSPPAP00000003540 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (246 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (651 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1201 aa) |
| | SERPINB6 | Serpin family B member 6; Belongs to the serpin family. (412 aa) |
| | LOC100989599 | Uncharacterized protein; Belongs to the cytochrome P450 family. (339 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (2687 aa) |
| | PENK | Proenkephalin. (267 aa) |
| | PRKRA | Protein activator of interferon induced protein kinase EIF2AK2. (261 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1017 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | BNIP3 | BCL2 interacting protein 3. (252 aa) |
| | PDK1 | Protein-serine/threonine kinase. (456 aa) |
| | CHCHD2 | Coiled-coil-helix-coiled-coil-helix domain containing 2. (151 aa) |
| | NFAT5 | Nuclear factor of activated T cells 5. (1548 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa) |
| | PRR5L | Proline rich 5 like. (368 aa) |
| | VKORC1L1 | VKc domain-containing protein. (97 aa) |
| | ENSPPAP00000039229 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | PLEC | Plectin. (4523 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) |
| | ENSPPAP00000038923 | Uncharacterized protein. (200 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | ADPRHL2 | ADP-ribosylhydrolase like 2. (364 aa) |
| | TMEM161A | Transmembrane protein 161A. (479 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa) |
| | GLRX2 | Glutaredoxin 2. (164 aa) |
| | ENSPPAP00000037516 | Uncharacterized protein. (321 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | ENSPPAP00000036950 | Uncharacterized protein. (128 aa) |
| | ENDOG | Endonuclease. (188 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa) |
| | MT3 | Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (113 aa) |
| | LOC100976049 | Uncharacterized protein. (280 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | STK39 | Serine/threonine kinase 39. (499 aa) |
| | ARG1 | Arginase. (322 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (789 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1356 aa) |
| | ENSPPAP00000035415 | Uncharacterized protein. (689 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa) |
| | ENSPPAP00000034946 | Uncharacterized protein. (276 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | MMP2 | Matrix metallopeptidase 2. (664 aa) |
| | ECT2 | Epithelial cell transforming 2. (914 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | FXN | Frataxin. (210 aa) |
| | ERMP1 | Endoplasmic reticulum metallopeptidase 1. (904 aa) |
| | GPX5 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (224 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (798 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) |
| | ENSPPAP00000033446 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | ATF4 | Activating transcription factor 4. (340 aa) |
| | MPO | Myeloperoxidase. (745 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (515 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (638 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | ENSPPAP00000032574 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (528 aa) |
| | NOS3 | Nitric oxide synthase 3. (997 aa) |
| | YBX3 | Y-box binding protein 3. (359 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (624 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1466 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | CDKN2A | Uncharacterized protein. (173 aa) |
| | SLC11A2 | Solute carrier family 11 member 2. (590 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | PCGF2 | Polycomb group ring finger 2. (344 aa) |
| | LONP1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (943 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (311 aa) |
| | BECN1 | Beclin 1. (450 aa) |
| | SLC4A11 | Solute carrier family 4 member 11. (918 aa) |
| | AQP5 | Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (252 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | AXL | AXL receptor tyrosine kinase. (894 aa) |
| | IL18BP | Interleukin 18 binding protein. (194 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (605 aa) |
| | RBM11 | RNA binding motif protein 11. (281 aa) |
| | NUDT2 | Nudix hydrolase 2. (147 aa) |
| | ENSPPAP00000028807 | Thioredoxin domain-containing protein. (166 aa) |
| | FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (543 aa) |
| | APOA4 | Apolipoprotein A4. (396 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (125 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa) |
| | SIGMAR1 | Uncharacterized protein. (134 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | ANKZF1 | Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (733 aa) |
| | NFE2L1 | Nuclear factor, erythroid 2 like 1. (772 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (390 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | TRPA1 | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1109 aa) |
| | BCL2 | BCL2 apoptosis regulator. (193 aa) |
| | ENSPPAP00000017817 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa) |
| | SELENON | Selenoprotein N. (495 aa) |
| | STAU1 | Staufen double-stranded RNA binding protein 1. (585 aa) |
| | CCS | Copper chaperone for superoxide dismutase. (274 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | IMPACT | Impact RWD domain protein. (310 aa) |
| | BRF2 | BRF2 RNA polymerase III transcription initiation factor subunit. (419 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | KDM6B | Lysine demethylase 6B. (1680 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (510 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (327 aa) |
| | VRK2 | VRK serine/threonine kinase 2. (508 aa) |
| | HDAC6 | Histone deacetylase 6. (1215 aa) |
| | NQO1 | NAD(P)H quinone dehydrogenase 1. (277 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | STX4 | Syntaxin 4; Belongs to the syntaxin family. (297 aa) |
| | ARL6IP5 | PRA1 family protein. (188 aa) |
| | ENSPPAP00000020965 | KH type-2 domain-containing protein. (250 aa) |
| | PDGFD | Platelet derived growth factor D. (329 aa) |
| | MPV17 | Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa) |
| | SLC12A6 | Solute carrier family 12 member 6. (1151 aa) |
| | ERRFI1 | ERBB receptor feedback inhibitor 1. (462 aa) |
| | PXN | Uncharacterized protein. (1087 aa) |
| | ENSPPAP00000021658 | Uncharacterized protein. (339 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa) |
| | PRDX2 | Peroxiredoxin 2. (198 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (784 aa) |
