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| | SRC | Tyrosine-protein kinase. (458 aa) |
| | LOC100992309 | C-C motif chemokine. (92 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | CCL1 | C-C motif chemokine. (96 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (264 aa) |
| | CCL20 | C-C motif chemokine. (96 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | CCL4 | C-C motif chemokine. (92 aa) |
| | LOC100986914 | Uncharacterized protein. (210 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (320 aa) |
| | YTHDC2 | YTH domain containing 2. (1430 aa) |
| | ENSPPAP00000004994 | TNF receptor-associated factor. (475 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (615 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) |
| | LOC100967628 | C-C motif chemokine. (93 aa) |
| | USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa) |
| | CD47 | CD47 molecule. (307 aa) |
| | AKAP12 | A-kinase anchoring protein 12. (1764 aa) |
| | NKX3-1 | NK3 homeobox 1. (223 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (710 aa) |
| | MYLK3 | Myosin light chain kinase 3. (819 aa) |
| | RBMX | RNA binding motif protein X-linked. (391 aa) |
| | NLRP7 | NLR family pyrin domain containing 7. (961 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (119 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | IL17A | Interleukin 17A. (155 aa) |
| | SIRPB1 | Uncharacterized protein. (427 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (772 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | TOLLIP | CUE domain-containing protein. (364 aa) |
| | ACOD1 | Aconitate decarboxylase 1. (490 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | EDN1 | Endothelin 1. (212 aa) |
| | GBP3 | Guanylate binding protein 3. (599 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | SIRPA | Signal regulatory protein alpha. (504 aa) |
| | HAS2 | Hyaluronan synthase 2. (552 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (492 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (595 aa) |
| | CCL25 | C-C motif chemokine ligand 25. (150 aa) |
| | SMPD1 | Saposin B-type domain-containing protein. (504 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | FGB | Fibrinogen beta chain. (491 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | CCL23 | C-C motif chemokine. (137 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (389 aa) |
| | CCL14 | C-C motif chemokine. (109 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | SFRP1 | NTR domain-containing protein. (178 aa) |
| | CCL15 | C-C motif chemokine. (113 aa) |
| | TNIP2 | CCHC NOA-type domain-containing protein. (322 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (637 aa) |
| | ANKRD1 | Ankyrin repeat domain 1. (319 aa) |
| | CCL16 | C-C motif chemokine. (120 aa) |
| | ST18 | ST18 C2H2C-type zinc finger transcription factor. (1047 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | HYAL3 | Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa) |
| | CD38 | CD38 molecule. (300 aa) |
| | GHR | Growth hormone receptor. (641 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | YY1 | Uncharacterized protein. (370 aa) |
| | ENSPPAP00000027817 | Uncharacterized protein. (56 aa) |
| | ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif 12. (1476 aa) |
| | ENSPPAP00000028661 | Protein kinase C. (574 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | PCSK1 | Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | ENSPPAP00000029844 | Uncharacterized protein. (229 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (311 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa) |
| | RORA | RAR related orphan receptor A. (559 aa) |
| | CCL18 | C-C motif chemokine. (89 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) |
| | XCL2 | X-C motif chemokine ligand 2. (114 aa) |
| | DAB2IP | DAB2 interacting protein. (1155 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (408 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1134 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | GBP2 | Guanylate binding protein 2. (591 aa) |
| | CCL8 | C-C motif chemokine. (109 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | MMP2 | Matrix metallopeptidase 2. (664 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | ENSPPAP00000035541 | CCHC NOA-type domain-containing protein. (372 aa) |
| | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7. (1646 aa) |
| | SELE | Selectin E. (612 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | CCL17 | C-C motif chemokine. (94 aa) |
| | CCL22 | C-C motif chemokine. (93 aa) |
| | FGG | Fibrinogen gamma chain. (461 aa) |
| | FN1 | Fibronectin 1. (2477 aa) |
| | CCL13 | C-C motif chemokine. (98 aa) |
| | ENSPPAP00000037876 | GB1/RHD3-type G domain-containing protein. (492 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | ENSPPAP00000038773 | RRM domain-containing protein. (327 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa) |
| | TRIM63 | Tripartite motif containing 63. (379 aa) |
| | CCL26 | C-C motif chemokine. (94 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | XCL1 | X-C motif chemokine ligand 1. (114 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1096 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
